Patents by Inventor Vladimir Genukh Beylin

Vladimir Genukh Beylin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isethionate salt of a selective CDK4 inhibitor
    Patent number: 7863278
    Abstract: Disclosed are polymorphs of the isethionate salt of 6-acetyl-8-cyclopentyl-5-methyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-8H-pyrido[2,3-d]pyrimidin-7-one, which is a selective cyclin-dependent kinase 4 (CDK4) inhibitor useful for treating inflammation and cell proliferative diseases such as cancer and restenosis.
    Type: Grant
    Filed: September 26, 2007
    Date of Patent: January 4, 2011
    Assignee: Warner-Lambert CompanyLLC
    Inventors: Vladimir Genukh Beylin, Anthony Clyde Blackburn, David Thomas Erdman, Peter Laurence Toogood
  • Hair growth promoting agents
    Patent number: 7655656
    Abstract: The present invention is directed to crystalline forms of 6-[[(3S,4R)-3,4-dihydro-3-hydroxy-6-[(3-hydroxypheny)sulfonyl]-2,2,3-trimethyl-2H-1-benzopyran-4-yl]oxy]-2-methyl-3(2H)-pyridazinone, formulations containing at least one of these crystalline forms and their use to promote hair growth.
    Type: Grant
    Filed: July 4, 2005
    Date of Patent: February 2, 2010
    Assignee: Pfizer Inc.
    Inventors: Vladimir Genukh Beylin, Javier Magano, Julie Kwon Spence, James Anthony Wesley
  • Hair Growth Promoting Agents
    Publication number: 20080318967
    Abstract: The present invention is directed to crystalline forms of 6-[[(3S,4R)-3,4-dihydro-3-hydroxy-6-[(3-hydroxyphenyl)sulfonyl]-2,2,3-trimethyl-2H-1-benzopyran-4-yl]oxy]-2-methyl-3(2H)-pyridazinone, formulations containing at least one of these crystalline forms and their use to promote hair growth.
    Type: Application
    Filed: July 4, 2005
    Publication date: December 25, 2008
    Applicant: PFIZER INC.
    Inventors: Vladimir Genukh Beylin, Javier Magano, Julie Kwon Spence, James Anthony Wesley
  • Crystalline Salts of 7-[4-(4-Naphthalen-1-Yl-Piperazin-1-Yl)-Butoxy]-3,4-Dihydro-1H-[1,8]Naphthyridine-2-One
    Publication number: 20080269242
    Abstract: The present application relates to crystalline salts of 7-[4-(4-naphthalen-1-yl-piperazin-1-yl)-butoxy]-3,4-di-hydro-1H-[1,8]naphthyridin-2-one, process for preparation of the crystalline salts, pharmaceutical compositions containing the crystalline salts, and use of the crystalline salts for treating certain disorders or conditions.
    Type: Application
    Filed: October 18, 2006
    Publication date: October 30, 2008
    Inventors: Vladimir Genukh Beylin, Nahid Yahyai
  • Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
    Patent number: 6960662
    Abstract: The present invention relates to a process for preparing 2-(pyridin-4-ylamino-pyrido [2,3-d]pyrimidine of Formula II by reacting a 4-aminopyridine of the formula with a 2-(4-imino-4H-pyridin-1-yl)-pyrido[2,3-d]pyrimidine of Formula I in the presence of a base. It also relates to an alternative process for preparing a compound of Formula II by reacting the aminopyridine hereinabove with in a unreactive organic solvent. It also relates to the compound of Formula III.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: November 1, 2005
    Assignee: Warner-Lambert Company
    Inventors: Vladimir Genukh Beylin, Richard Jungkyu Lee, Mark Eugene Marlatt
  • Process for preparing 2-(4-pyridyl)amino-6-dialkyloxyphenyl-pyrido[2,3-d]pyrimidin-7-ones
    Publication number: 20030216415
    Abstract: Process for preparing 2-pyridylamino-pyrido[2,3-d]pyrimidines of Formula (II) wherein Ar is aryl, R′ and R″ are hydrogen, alkyl, alkoxy, or phenyl, and R2 is alkyl.
    Type: Application
    Filed: February 4, 2003
    Publication date: November 20, 2003
    Inventors: Vladimir Genukh Beylin, Richard Jungkyu Lee, Mark Eugene Marlatt
  • Chiral [[(2-bromoethyl)-amino]methyl]-2-nitro-1H-imidazol-1-ethanol and related compounds
    Patent number: 5659048
    Abstract: Chiral compounds useful as radiosensitizers or chemosensitizers having the formula ##STR1## wherein X is halogen or ##STR2## intermediates used to prepare these compounds, and a novel process to prepare these compounds are described.
    Type: Grant
    Filed: May 23, 1995
    Date of Patent: August 19, 1997
    Assignees: British Technology Group Limited, Warner-Lambert Company
    Inventors: Vladimir Genukh Beylin, Anthony Denver Sercel, Howard Daniel Hollis Showalter, Gerald Edward Adams, Edward Martin Fielden, Matthew Alexander Naylor, Ian James Stratford
  • Process for preparing chiral [[(2-bromoethyl)-amino]methyl]-2-nitro-1H-imidazol-1-ethanol and related compounds
    Patent number: 5342959
    Abstract: Chiral compounds useful as radiosensitizers or chemosensitizers having the formula ##STR1## wherein X is halogen or ##STR2## intermediates used to prepare these compounds, and a novel process to prepare these compounds are described.
    Type: Grant
    Filed: August 5, 1993
    Date of Patent: August 30, 1994
    Assignees: Warner-Lambert Company, British Tech. Group
    Inventors: Vladimir Genukh Beylin, Anthony D. Sercel, Howard D. H. Showalter, Gerald E. Adams, Edward M. Fielden, Matthew A. Naylor, Ian J. Stratford