Patents by Inventor Vladimir Grigorevich Granik

Vladimir Grigorevich Granik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antithrombotic and antiatherosclerotic agent and method for producing same (variants)
    Patent number: 9453008
    Abstract: The invention relates to the field of chemical and pharmaceutical industry and medicine and concerns compounds which can be used to produce agents for the treatment of cardiovascular diseases. The use of 2-[2-cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula I is proposed as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, a platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. Variants of methods for synthesizing the above compound are also proposed.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: September 27, 2016
    Assignee: PROTON OOO
    Inventors: Svetlana Yurevna Ryabova, Valery Aleksandrovich Parshin, Vladimir Grigorevich Granik, Nikita Borisovich Grigoriev, Ludmila Mikhaylovna Alekseeva
  • NOVEL ANTITHROMBOTIC AND ANTIATHEROSCLEROTIC AGENT AND METHOD FOR PRODUCING SAME (VARIANTS)
    Publication number: 20140235868
    Abstract: The invention relates to the field of chemical and pharmaceutical industry and medicine and concerns compounds which can be used to produce agents for the treatment of cardiovascular diseases. The use of 2-[2-cyano-2-[5-(hydroxymethyl)-3-methyl-1,3-oxazolidin-2-ylidene]ethylidene]indolin-3-one of formula I is proposed as a biologically active compound exhibiting the properties of exogenous nitric oxide donor, a platelet aggregation inhibitor, also exhibiting antihypertensive activity and activating activity towards the soluble guanylate cyclase enzyme. Variants of methods for synthesizing the above compound are also proposed.
    Type: Application
    Filed: October 29, 2012
    Publication date: August 21, 2014
    Applicant: PROTON OOO
    Inventors: Svetlana Yurevna Ryabova, Valery Aleksandrovich Parshin, Vladimir Grigorevich Granik, Vladimir Vladimirovich Grank, Nikta Borisovich Grigoriev, Ludmila Mikhaylovna Aleksseva
  • Pyridopyrazindione derivative and its use as an antiulcer drug
    Patent number: 8440670
    Abstract: The invention relates to the fields of the chemical and pharmaceutical industry and medicine and concerns a novel compound which can be used as an antiulcer agent. The compound is 9 -(quinony-2)-2-p-ethoxyphenylethyl-4,5,6,7,8,9,10,11-octahydropyrido [1,2-a]pyrazindione-1,4 of formula (I), or pharmaceutically acceptable complex derivatives thereof. The compound can be used as an antiulcer agent.
    Type: Grant
    Filed: September 3, 2012
    Date of Patent: May 14, 2013
    Assignee: Innovative Pharmacology Research OOO (IPHAR)
    Inventors: Vladimir Grigorevich Granik, Valeriya Markovna Ljubchanskaya, Valery Aleksandrovich Parshin, Marina Alekseevna Kalinkina
  • NEW BIOLOGICALLY ACTIVE COMPOUND N-[3-(4-NITROPHENYLAMINO)-INDOLE-2-ILMETHYLENE]AMINOGUANIDINE HYDROCHLORIDE WITH ANTI-INFLAMMATORY ACTIVITY
    Publication number: 20130012724
    Abstract: The present invention relates to chemical-pharmaceutical industry and medicine. The present invention relates to N-[3-(4-nitrophenylamino)-indole-2-ilmethylene]aminoguanidine hydrochloride of formula (2) having anti-inflammatory and chondroprotective activity. The compound does not exhibit adverse effects.
    Type: Application
    Filed: March 11, 2011
    Publication date: January 10, 2013
    Applicant: INPHARMA
    Inventors: Svetlana Yurevna Ryabova, Valery Aleksandrovich Parshin, Marina Alekseevna Kalinkina, Vladimir Grigorevich Granik, Vladimir Vladimirovich Granik, Nikita Borisovich Grigoriev, Viktoriya Isaakovna Levina, Elena Konstantinovna Panisheva, Sergey Anatolevich Zaycev