Patents by Inventor Vladimir Jakovlev

Vladimir Jakovlev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4643995
    Abstract: There are disclosed pyridine-2-ethers and pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring corresponding to the formula ##STR1## the pyridine-N-oxides and/or amine oxides thereof and the pharmaceutically acceptable salts thereof. The compounds show analgesic activity.
    Type: Grant
    Filed: December 17, 1984
    Date of Patent: February 17, 1987
    Assignee: Degussa Aktiengesellschaft
    Inventors: Jurgen Engel, Vladimir Jakovlev, Bernd Nickel, Klaus Thiemer, Gerhard Scheffler
  • Patent number: 4547505
    Abstract: There are prepared new pharmacologically active compounds of the formula: ##STR1## In formula I R.sub.1 is a phenyl radical, pyridyl radical, a pyrimidyl group, or pyrazinyl radical, or a phenyl radical, pyridiyl radical, pyrimidyl radical, or pyrazinyl radical substituted by the radicals R.sub.3 and R.sub.4 which are the same or different and are hydrogen, fluorine, chlorine, bromine, trifluoromethyl, hydroxyl, C.sub.1 -C.sub.6 -alkyl groups C.sub.1 -C.sub.6 -alkoxy groups, C.sub.3 -C.sub.6 -alkenyloxy groups, C.sub.3 -C.sub.6 -cycloalkyloxy groups, phenyl-C.sub.1 -C.sub.4 -alkoxy groups, C.sub.1 -C.sub.6 -alkylmercapto groups, the nitro group, the amino group, C.sub.1 -C.sub.6 -dialkylamino groups, C.sub.2 -C.sub.6 -alkanoyl groups, C.sub.2 -C.sub.6 -alkanoylamino groups, or C.sub.2 -C.sub.6 -alkanoyloxy groups and R.sub.2 is the adamantyl group, the 3,3-dimethyl-bicyclo[2.2.1]hept-2-yl radical, a saturated C.sub.3 -C.sub.16 -cycloalkenyl radical and alk is a straight or branched C.sub.1 -C.sub.
    Type: Grant
    Filed: February 24, 1984
    Date of Patent: October 15, 1985
    Assignee: Degussa Aktiengesellschaft
    Inventors: Gerhard Oepen, Jurgen Engel, Vladimir Jakovlev, Klaus Thiemer
  • Patent number: 4335126
    Abstract: There are prepared compounds corresponding to the general formula ##STR1## in which R.sup.1 is a hydrogen atom, a C.sub.2 to C.sub.6 -alkanoyl group, a C.sub.3 to C.sub.6 -alkenoyl group, a C.sub.3 to C.sub.6 -cycloalkyl carbonyl group, a benzoyl group, an alkoxybenzoyl group, a nicotinoyl group, a thienyl carbonyl group, a furyl carbonyl group, a phenylacetyl group or a C.sub.1 to C.sub.4 -alkoxyphenyl acetyl group and R.sup.2 represents a phenyl, naphthyl or pyridyl group or such group substituted by the groups R.sup.3 and R.sup.4, the groups R.sup.3 and R.sup.4, which may be the same or different, each representing hydrogen, hydroxyl, fluorine, chlorine, bromine, a nitro group, a trifluoromethyl group, a C.sub.1 to C.sub.6 -alkyl group, a C.sub.1 to C.sub.6 -alkoxy group, a C.sub.1 to C.sub.6 -alkyl thio group, a C.sub.1 to C.sub.6 -alkyl sulphonyl group, a C.sub.2 to C.sub.6 -alkanoyl group, an amino group, an acylamino group or an acyloxy group in which the acyl is of the type defined in respect to R.
    Type: Grant
    Filed: October 3, 1980
    Date of Patent: June 15, 1982
    Assignee: Degussa Aktiengesellschaft
    Inventors: Axel Kleemann, Vladimir Jakovlev, Klaus Thiemer, Jurgen Engel
  • Patent number: 4207322
    Abstract: There are produced 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-(1,4)-diazepines of the formula: ##STR1## wherein R.sub.1 is hydrogen, a halogen atom, an alkyl mercapto group having 1 to 6 carbon atoms,R.sub.2 is hydrogen, an alkyl group with 1 to 6 carbon atoms,R.sub.3 is hydrogen or a halogen or a halogen atomthe structural part A-B is the group --CH.sub.2 .dbd.NH--and Y-Z is the group >C.dbd.N--, >C.dbd.N(.fwdarw.O), and Y-Z is the group >C.dbd.N--, their optical isomers and their pharmaceutically acceptable salts. The compounds have anticonvulsive properties.
    Type: Grant
    Filed: July 20, 1978
    Date of Patent: June 10, 1980
    Assignee: Deutsche Gold- und Silber-Scheideanstalt vormals Roessler
    Inventors: Walter von Bebenburg, Norbert Schulmeyer, Vladimir Jakovlev
  • Patent number: 4110455
    Abstract: There are produced 6-aryl-s-triazolo-(4,3-a)-pyrido-(2,3-f)-(1,4)-diazepines of the formula: ##STR1## wherein R.sub.1 is hydrogen, a halogen atom, an alkyl group with 1 to 6 carbon atoms, a hydroxy group, an alkoxy group with 1 to 6 carbon atoms, a mercapto group, an alkyl mercapto group having 1 to 6 carbon atoms, an alkylsulfoxido group with 1 to 6 carbon atoms, an alkyl sulfono group with 1 to 6 carbon atoms, an amino group, an aliphatic acylamino group with 2 to 6 carbon atoms, a monoalkylamino group with 1 to 6 carb0n atoms, a dialkylamino group with 1 to 6 carbon atoms in each alkyl group or a saturated heterocyclic amino group having 5 to 7 members in the ring including 1 to 2 nitrogen atoms and 0 to 1 oxygen atoms in the ring,R.sub.
    Type: Grant
    Filed: October 26, 1976
    Date of Patent: August 29, 1978
    Assignee: Deutsche Gold- und Silber-Scheideanstalt vormals Roessler
    Inventors: Walter von Bebenburg, Norbert Schulmeyer, Vladimir Jakovlev