Patents by Inventor Vladimir M. Zakhariev

Vladimir M. Zakhariev has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Column device for isolation and labeling of nucleic acids
    Patent number: 6818398
    Abstract: A method for manipulating genetic material, the method comprising disrupting cells so as to liberate genetic material contained in the cells; contacting the genetic material to a silica column in a manner to cause the genetic material to become immobilized to the column; labeling the immobilized genetic material; and eluting the labeled material from the column. Also provided is a two-buffer process for manipulating genetic material, the process comprising: contacting cells containing the genetic material to a silica column; creating a first fraction of cell detritus and a second fraction containing the genetic material; confining the genetic material to the column; removing the cell detritus; contacting the genetic material with radicals so as to produce reactive aldehyde groups on the genetic material, and attaching chromophore to the genetic material.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: November 16, 2004
    Assignee: The University of Chicago
    Inventors: Sergei G. Bavykin, James P. Akowski, Vladimir M. Zakhariev, Andrei Mirzabekov
  • Column device for isolation and labeling of nucleic acids
    Publication number: 20030096229
    Abstract: A method for manipulating genetic material, the method comprising disrupting cells so as to liberate genetic material contained in the cells; contacting the genetic material to a silica column in a manner to cause the genetic material to become immobilized to the column; labeling the immobilized genetic material; and eluting the labeled material from the column. Also provided is a two-buffer process for manipulating genetic material, the process comprising: contacting cells containing the genetic material to a silica column; creating a first fraction of cell detritus and a second fraction containing the genetic material; confining the genetic material to the column; removing the cell detritus; contacting the genetic material with radicals so as to produce reactive aldehyde groups on the genetic material, and attaching chromophore to the genetic material.
    Type: Application
    Filed: December 29, 2000
    Publication date: May 22, 2003
    Inventors: Sergei G. Bavykin, James P. Akowski, Vladimir M. Zakhariev, Andrei Mirzabekov