Patents by Inventor Vladimir Mironov

Vladimir Mironov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7968765
    Abstract: The present invention concerns a method for improving growth characteristics of plants by increasing expression and/or activity in a plant of an LRR receptor kinase or a homologue thereof. One such method comprises introducing into a plant an RLK827 nucleic acid molecule or functional variant thereof. The invention also relates to transgenic plants having improved growth characteristics, which plants have modulated expression of a nucleic acid encoding an LRR receptor kinase. The present invention also concerns constructs useful in the methods of the invention.
    Type: Grant
    Filed: July 14, 2005
    Date of Patent: June 28, 2011
    Assignee: CropDesign N.V.
    Inventors: Valerie Frankard, Ana Isabel Sanz Molinero, Vladimir Mironov
  • Patent number: 7932432
    Abstract: The present invention concerns a method for modifying the growth characteristics of a plant relative to corresponding wild type plants, comprising modifying expression in a plant of a seedy1 nucleic acid and/or modifying the level and/or activity in a plant of a seedy1 protein. The invention also concerns novel constructs and novel seedy1 nucleic acid and protein sequences.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: April 26, 2011
    Assignee: Crop Design N.V.
    Inventors: Valerie Frankard, Vladimir Mironov
  • Patent number: 7919678
    Abstract: The present invention concerns a method for modifying plant growth characteristics by modifying expression in a plant of a nucleic acid encoding a methionine aminopeptidase (MAP protein) and/or by modifying level and/or activity in a plant of a MAP protein. The invention also relates to transgenic plants having modified growth characteristics, which plants have modified expression of a nucleic acid encoding a MAP protein. Particularly the present invention discloses a method to increase yield of a plant, preferably in a cereal such as rice or corn.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: April 5, 2011
    Assignee: Cropdesign N.V.
    Inventor: Vladimir Mironov
  • Patent number: 7825295
    Abstract: The present invention provides a method for modulating endoreduplication in a plant, plant part, or plant cell. The method comprises the steps of introduction and expression of a nucleotide sequence encoding the CDC2bAt cyclin dependent kinase gene disclosed in database accession number X57840 or said CDC2bAt cyclin dependent kinase gene having the Asp residue at position 161 replaced with an Asn residue, under the control of a promoter which functions in a plant.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: November 2, 2010
    Assignee: CropDesign N.V.
    Inventors: Dirk Inze, Gerda Segers, Lieven De Veylder, Vladimir Mironov
  • Patent number: 7807872
    Abstract: The present invention provides isolated nucleic acid molecules encoding plant cyclin dependent kinase inhibitors (ICKs). The nucleic acid molecules may be used to downregulate expression of a plant ICK, thereby providing useful plant phenotypes.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: October 5, 2010
    Assignee: CropDesign N.V.
    Inventors: Valérie Marie-Noëlle S. Frankard, Adrian Marius Peres Bota, Anne-Marie Droual, Vladimir Mironov, Dirk Inze, Yves Hatzfeld
  • Publication number: 20100229260
    Abstract: The present invention relates to T-DNA vectors and methods for obtaining transgenic eukaryotes using said vectors. The transgenic eukaryotes are characterized in that they contain the T-DNA but not the illegitimately transferred vector backbone sequence. This is achieved by modifying the T-DNA borders such that they are more efficiently nicked or such that they allow elimination of illegitimately transferred vector backbone sequences by means of recombination.
    Type: Application
    Filed: May 19, 2010
    Publication date: September 9, 2010
    Applicant: CROPDESIGN N.V.
    Inventors: ANNA DEPICKER, VLADIMIR MIRONOV, FRANKY TERRAS, WILLEM BROEKAERT, SYLVIE DE BUCK, CHRIS DE WILDE
  • Publication number: 20100218271
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important characteristics in plants. More specifically, the present invention concerns a method for improving yield-related traits, such as enhanced yield and/or enhanced growth, or modified content of storage compounds in plants by modulating expression in a plant of a nucleic acid encoding a GRP (Growth Related Protein) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding a GRP polypeptide, which plants have improved characterisitics relative to control plants. The invention also provides hitherto unknown GRP-encoding nucleic acids, and constructs comprising the same, useful in performing the methods of the invention.
    Type: Application
    Filed: August 2, 2007
    Publication date: August 26, 2010
    Applicant: Crop Design N.V.
    Inventors: Ana Isabel Sanz Molinero, Christophe Reuzeau, Valerie Frankard, Vladimir Mironov
  • Patent number: 7749751
    Abstract: The present invention relates to T-DNA vectors and methods for obtaining transgenic eukaryotes using said vectors. The transgenic eukaryotes are characterized in that they contain the T-DNA but not the illegitimately transferred vector backbone sequence. This is achieved by modifying the T-DNA borders such that they are more efficiently nicked or such that they allow elimination of illegitimately transferred vector backbone sequences by means of recombination.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: July 6, 2010
    Assignee: CropDesign N.V.
    Inventors: Anna Depicker, Vladimir Mironov, Franky Terras, Willem Broekaert, Sylvie De Buck, Chris De Wilde
  • Publication number: 20090271895
    Abstract: The present invention concerns a method for improving growth characteristics of plants by increasing activity and/or expression in a plant of an SnRK2 kinase or a homologue thereof. One such method comprises introducing into a plant an SnRK2 nucleic acid molecule or functional variant thereof. The invention also relates to transgenic plants having improved growth characteristics, which plants have modulated expression of a nucleic acid encoding an SnRK2 kinase. The present invention also concerns constructs useful in the methods of the invention.
    Type: Application
    Filed: July 14, 2005
    Publication date: October 29, 2009
    Applicant: CROPDESIGN N.V.
    Inventors: Valerie Frankard, Vladimir Mironov
  • Publication number: 20090241218
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving various plant growth characteristics by modulating expression in a plant of a nucleic acid encoding a GRP (Growth-Related Protein). The present invention also concerns plants having modulated expression of a nucleic acid encoding a GRP, which plants have improved growth characteristics relative to corresponding wild type plants or other control plants. The invention also provides constructs useful in the methods of the invention. The GRP may be one of the following: Extensin Receptor-Like Kinase (ERLK), F-Box WD40 (FBXW) polypeptide, RAN-Binding Protein (RANBP), Golden2-like Transcription Factor (GLK), REV delta homeodomain leucine zipper domain polypeptide, CLE protein, and Seed Yield Regulator (SYR) protein.
    Type: Application
    Filed: May 30, 2007
    Publication date: September 24, 2009
    Applicant: CropDesign N.V.
    Inventors: Valerie Frankard, Vladimir Mironov, Christophe Reuzeau
  • Patent number: 7592507
    Abstract: The present invention relates to a method for modifying plant growth and development processes by affecting cell cycle regulation comprising modulating expression of members of the plant E2F transcription factor family. More specific the invention relates to methods for stimulating cell division in a plant. The invention further relates to transgenic plants produced by the methods of the invention having altered plant growth and development characteristics compared to their isogenic counterparts. Preferably, the plant characteristics modified by the present invention include enlarged cotyledons, enhanced growth rate, stress resistance and seedling survival, more cells, more tillers, more panicles.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: September 22, 2009
    Assignee: CrooDesign, N.V.
    Inventors: Tom Beeckman, Lieven De Veylder, Dirk Inze, Vladimir Mironov, Willem Broekaert, Willy Dillen, Valerie Frankard
  • Publication number: 20090235393
    Abstract: The present invention concerns a method for modifying the growth characteristics of a plant relative to corresponding wild type plants, comprising modifying expression in a plant of a seedy1 nucleic acid and/or modifying the level and/or activity in a plant of a seedy1 protein. The invention also concerns novel constructs and novel seedy1 nucleic acid and protein sequences.
    Type: Application
    Filed: November 19, 2004
    Publication date: September 17, 2009
    Applicant: CropDesign N.V.
    Inventors: Valerie Frankard, Vladimir Mironov
  • Publication number: 20090222952
    Abstract: The present invention concerns a method for increasing plant yield and/or increased stress resistance by decreasing the level of activity of a DEL1 polypeptide. One such method comprises introducing into a plant a nucleic acid comprising a variant DEL1 nucleic acid. Another method comprises downregulating expression of a DEL1 gene. The invention also relates to transgenic plants having introduced therein a variant DEL1 nucleic acid thereof, which plants have increased yield and/or increased stress resistance relative to control plants. The present invention also concerns a novel DEL1 protein and its encoding sequence, and constructs useful in the methods of the invention.
    Type: Application
    Filed: November 8, 2006
    Publication date: September 3, 2009
    Applicants: CropDesign N.V., VIB vzw, Universiteit Gent
    Inventors: Jan de Meutter, Vladimir Mironov, Christophe Reuzeau, Dirk Inze, Kobe Vlieghe, Lieven de Veylder
  • Publication number: 20080163394
    Abstract: The present invention concerns a method for increasing plant yield relative to corresponding wild type plants. More specifically, the present invention concerns a method for increasing plant yield comprising introducing into a plant a nucleic acid encoding a cyclin D3 (CYCD3) polypeptide under the control of a promoter capable of preferentially expressing the nucleic acid in the endosperm of seeds. The present invention also concerns plants comprising an isolated nucleic acid encoding a CYCD3 polypeptide under the control of a promoter capable of preferentially expressing the nucleic acid in the endosperm of seeds, which plants have increased yield relative to corresponding wild type plants. The invention also provides constructs useful in the methods of the invention.
    Type: Application
    Filed: March 24, 2006
    Publication date: July 3, 2008
    Applicant: CropDesign N.V.
    Inventors: Valerie Frankard, Vladimir Mironov
  • Publication number: 20080127365
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for improving plant growth characteristics relative to corresponding wild type plants. More specifically, the present invention concerns a method for improving plant growth characteristics comprising modulating expression in a plant of a nucleic acid encoding a class I homeodomain leucine zipper (HDZip) hox5 polypeptide or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a nitrate transporter protein (NRT) or a homologue thereof; or comprising modulating expression in a plant of a nucleic acid encoding a polypeptide denoted Yield Enhancing Protein 16 (YEP16); or comprising modulating expression in a plant of a Group I glycogen synthase kinase (Group I shaggy-like kinase) or a homologue thereof.
    Type: Application
    Filed: April 30, 2007
    Publication date: May 29, 2008
    Applicant: CropDesign N.V.
    Inventors: Ana Isabel Sanz Molinero, Christophe Reuzeau, Yves Hatzfeld, Veronique Boudolf, Lieven de Veylder, Dirk Inze, Vladimir Mironov
  • Publication number: 20080070304
    Abstract: A composition comprising a plurality of cell aggregates for use in the production of engineered organotypic tissue by organ printing. A method of making a plurality of cell aggregates comprises centrifuging a cell suspension to form a pellet, extruding the pellet through an orifice, and cutting the extruded pellet into pieces. Apparatus for making cell aggregates comprises an extrusion system and a cutting system. In a method of organ printing, a plurality of cell aggregates are embedded in a polymeric or gel matrix and allowed to fuse to form a desired three-dimensional tissue structure. An intermediate product comprises at least one layer of matrix and a plurality of cell aggregates embedded therein in a predetermined pattern. Modeling methods predict the structural evolution of fusing cell aggregates for combinations of cell type, matrix, and embedding patterns to enable selection of organ printing processes parameters for use in producing an engineered tissue having a desired three-dimensional structure.
    Type: Application
    Filed: February 24, 2005
    Publication date: March 20, 2008
    Applicant: The Curators of the Univeristy of Missouri
    Inventors: Gabor Forgacs, Karoly Jakab, Adrian Neagu, Vladimir Mironov
  • Publication number: 20080047035
    Abstract: The present invention relates to T-DNA vectors and methods for obtaining transgenic eukaryotes using said vectors. The transgenic eukaryotes are characterized in that they contain the T-DNA but not the illegitimately transferred vector backbone sequence. This is achieved by modifying the T-DNA borders such that they are more efficiently nicked or such that they allow elimination of illegitimately transferred vector backbone sequences by means of recombination.
    Type: Application
    Filed: December 13, 2000
    Publication date: February 21, 2008
    Inventors: Anna Depicker, Vladimir Mironov, Franky Terras, Willem Broekaert, Sylvie De Buck, Chris De Wilde
  • Publication number: 20070199085
    Abstract: The present invention concerns a method for modifying the growth characteristics of plants by modulating expression in a plant of a B-type CDK nucleic acid and/or modulating activity and/or levels in a plant of a B-type CDK protein. The invention also relates to transgenic plants having modified growth characteristics, which plants have modulated expression of a B-type CDK nucleic acid and/or modulated activity and/or levels in a plant of a B-type CDK protein relative to expression, activity and/or levels in corresponding wild-type plants. The present invention also provides a novel screening method for the identification of mutant CDKs having enhanced CDK activity relative to corresponding non-mutated CDKs. The present invention also provides a novel screening method for the identification of non-active CDKs that are able to bind to CKIs (cyclin dependent kinase inhibitors). The invention also provides mutant CDKs obtainable by the screening methods according to the invention.
    Type: Application
    Filed: September 3, 2004
    Publication date: August 23, 2007
    Inventors: Willem Broekaert, Valerie Frankard, Yves Hatzfeld, Vladimir Mironov
  • Publication number: 20070136889
    Abstract: The present invention provides a new Arabidopsis thaliana nucleotide sequence and polypeptide sequence having a molecular weight of about 10.5 kDa. Modulation of the expression of the polypeptides encoded by the nucleotide sequences according to the invention has an advantageous influence on plant cell division characteristics especially on the endoreduplication whereby plant cell size and storage capacity of plant cells is influenced.
    Type: Application
    Filed: January 26, 2007
    Publication date: June 14, 2007
    Inventors: Dirk Inze, Gerda Segers, Lieven Veylder, Vladimir Mironov
  • Publication number: 20070118931
    Abstract: The present invention concerns a method for modifying the growth characteristics of plants by modulating expression in a plant of a nucleic acid sequence encoding a GRUBX protein and/or modulating activity and/or levels in a plant of a GRUBX protein. The present invention furthermore provides novel GRUBX proteins and nucleic acids encoding such proteins. The invention also relates to constructs comprising GRUBX encoding nucleic acids, and transgenic plants having modified growth characteristics, which plants have modulated expression of a nucleic acid encoding a GRUBX protein.
    Type: Application
    Filed: December 17, 2004
    Publication date: May 24, 2007
    Applicant: CROPDESIGN N.V.
    Inventors: Valerie Frankard, Vladimir Mironov, Ana Sanz Molinero