Abstract: Provided are systems and methods for blood pressure assessment using a wrist and cardiac device. In one embodiment, the wrist device receives a synchronization pulse, indicating cardiac onset, and generates blood-arrival signal data. In another embodiment, the wrist device receives cardiac signal data and generates blood-arrival signal data. The synchronization pulse or the cardiac signal data and the blood-arrival data are synchronized. The synchronization pulse or cardiac signal data and the blood-arrival signal data are processed to determine a pulse transit time between the heart and the wrist device. This pulse transit time and patient parameter are input into a trained neural network to generate an assessed blood pressure. The cardiac signal data can be generated by an electrical, acoustical, echocardiographic, or ballistocardiograph sensor. The blood-arrival signal data can be generated by an optical sensor, a tonometry sensor or a pressure-sensing sensor.

Abstract: The invention relates to systems and methods for performing one or more immunoassays on a fluid sample and performing image analysis on the fluid sample as the sample is flowing so as to obtain measurements related to one or more target analytes based on image analysis. The systems and methods include a disposable fluidic device, such as a cartridge, configured to be loaded with a fluid sample and perform one or more assays on the fluid sample. The cartridge is further configured to flow a volume of fluid sample, undergoing, or having undergone, an assay, through a portion thereof to be subsequently analyzed by an analysis instrument. The analysis instrument is configured to capture images of the fluid sample as it is flowing through a portion of the cartridge and subsequently analyze the images so as to obtain measurements of one or more target analytes within the fluid sample.

Abstract: The finger-operated input device connectable to a digital device is disclosed. The aforesaid input device comprises (a) a sensing pad being responsive to displacement of the finger substantially parallel to the pad in a reach range thereof and transmitting electrical signals in response thereto; and (b) an analyzing unit arranged to receive said electrical signals and calculate a data defining trajectory of the finger and transmit the data to the digital device; The sensing pad comprises at least three sensors perceptive to motion of the finger relative to the sensors.