Patents by Inventor Vladimir Y. VVEDENSKIY

Vladimir Y. VVEDENSKIY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES
    Publication number: 20230159458
    Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.
    Type: Application
    Filed: August 3, 2022
    Publication date: May 25, 2023
    Applicant: AM Chemicals LLC
    Inventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY, Khirud GOGOI
  • Solid supports and phosphoramidite building blocks for oligonucleotide conjugates
    Patent number: 11447451
    Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: September 20, 2022
    Assignee: AM Chemicals LLC
    Inventors: Andrei Pavel Guzaev, Vladimir Y. VVedenskiy, Khirud Gogoi
  • Solid supports and phosphoramidite building blocks for oligonucleotide conjugates
    Patent number: 10781175
    Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: September 22, 2020
    Assignee: AM CHEMICALS LLC
    Inventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy, Khirud Gogoi
  • SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES
    Publication number: 20200277260
    Abstract: Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.
    Type: Application
    Filed: May 19, 2020
    Publication date: September 3, 2020
    Applicant: AM Chemicals LLC
    Inventors: Andrei Pavel Guzaev, Vladimir Y. VVedenskiy, Khirud Gogoi
  • Phosphoramidite building blocks for sugar-conjugated oligonucleotides
    Patent number: 10669301
    Abstract: Methods of preparing synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide are disclosed, where the synthetic oligonucleotides are prepared from nucleosidic phosphoramidite building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: June 2, 2020
    Assignee: AM CHEMICALS LLC
    Inventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy
  • PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES
    Publication number: 20180362572
    Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 20, 2018
    Applicant: AM CHEMICALS LLC
    Inventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY
  • Phosphoramidite building blocks for sugar-conjugated oligonucleotides
    Patent number: 10087208
    Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: October 2, 2018
    Assignee: AM CHEMICALS LLC
    Inventors: Andrei Pavel Guzaev, Vladimir Y. Vvedenskiy
  • PHOSPHORAMIDITE BUILDING BLOCKS FOR SUGAR-CONJUGATED OLIGONUCLEOTIDES
    Publication number: 20160083414
    Abstract: Novel nucleoside phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one phosphotriester linkage conjugated to a monosaccharide and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said building blocks, preferably followed by removal of protecting groups to provide monosaccharide-conjugated oligonucleotides.
    Type: Application
    Filed: December 4, 2015
    Publication date: March 24, 2016
    Applicant: AM CHEMICALS LLC
    Inventors: Andrei Pavel GUZAEV, Vladimir Y. VVEDENSKIY