Abstract: Methods for assessment of pelvic floor conditions based on tactile imaging are described. The vaginal wall is deformed before and after an interventional procedure using a transvaginal probe equipped with tactile pressure sensors and a motion tracking sensor. The vaginal wall coordinates and pressure patterns are obtained during the examination and used to build 3-D tactile image of the vagina and to calculate elasticity modulus profiles and spacing profiles along selected lines inside 3-D tactile image. The “before” and “after” profile values at specified locations are then compared to each other and to thresholds or profiles for normal conditions of vagina and its support structures. Methods of the invention may be used in estimating an improvement after an interventional procedure such as pelvic tissue regeneration, muscle repair or implantation of a supporting structure.