Abstract: A method of making a sterile connection comprises mating a first fitting having an aperture and a second fitting having an aperture, removing first and second strip out layers from between the end surfaces of sealed first and second resilient sealing members, and contacting the end surfaces of the resilient sealing members to provide fluid communication between the aperture of the first fitting and the aperture of the second fitting. A connector assembly comprises first and second fittings, a stem mounted for axial movement through the first fitting into the second fitting, and a deformable locking device which selectively prevents axial movement of the stem in the first fitting.

Abstract: A connector assembly and a fluid system or device comprises a connector assembly which includes first and second fittings, each fitting having an aperture, a first cap, and a stem disposed in the aperture of the first fitting. In various embodiments of the invention, the connector assembly further comprises a socket cooperatively arranged with one of the first and second fittings and at least one resilient sealing member. A method for making a connection includes removing a cap, mating first and second fittings, removing a stripout layer, and establishing a fluid flowpath through the first and second fittings.

Abstract: A connector or a connector assembly comprises a fitting, a resilient sealing member, a plurality of protrusions, and a removable stripout layer. The fitting includes a socket. The protrusions extend from the fitting and are connectable to a mating connector. The resilient sealing layer, which is disposed in the socket of the fitting, includes a hollow body having opposite open ends and an internal passage extending between the open ends. The removable stripout layer is movable between a first position in which the stripout layer overlies an end of the resilient sealing member and a second position in which the stripout layer is removed from the end of the resilient sealing member.

Abstract: A connector or a connector assembly comprises a fitting, a resilient sealing member, a plurality of protrusions, and a removable stripout layer. The fitting includes a socket. The protrusions extend from the fitting and are connectable to a mating connector. The resilient sealing layer, which is disposed in the socket of the fitting, includes a hollow body having opposite open ends and an internal passage extending between the open ends. The removable stripout layer is movable between a first position in which the stripout layer overlies an end of the resilient sealing member and a second position in which the stripout layer is removed from the end of the resilient sealing member.

Abstract: A connector assembly and a fluid system or device comprise a connector assembly which includes first and second fittings, each fitting having an aperture, and a stem disposed in the aperture of the first fitting. In various embodiments of the invention, the connector assembly may further comprise a socket cooperatively arranged with one of the first and second fittings, at least one resilient sealing member, a sealing layer joined to the socket or covering the resilient sealing member, and/or a deformable locking device. A method for making a connection includes mating a first fitting having an aperture and a second fitting having an aperture without fluid within the first and second fittings, establishing a fluid flowpath through the first and second fittings by advancing a stem having a head through the aperture of the first fitting into the aperture of the second fitting, and establishing fluid flow through the first and second fittings by opening a fluid blocking mechanism.

Abstract: A fluid delivery system includes a connector assembly and a container for holding fluids. The connector assembly includes a first fitting defining a first aperture and a second fitting that is couplable to the first fitting and defines a second aperture. The container for holding fluids including a fitment, wherein one of the first and second fittings is directly coupled to the fitment.

Abstract: A fluid delivery system includes a connector assembly and a container for holding fluids. The connector assembly includes a first fitting defining a first aperture and a second fitting that is couplable to the first fitting and defines a second aperture. The container for holding fluids including a fitment, wherein one of the first and second fittings is directly coupled to the fitment.

Abstract: A fluid delivery system includes a connector assembly and a container. The connector assembly includes a first fitting defining a first aperture, a second fitting that is couplable to the first fitting and defines a second aperture, and a removable contamination containment layer sealing at least one of the first and second apertures. One of the first and second fittings is associated with the container.

Abstract: Biological fluid processing assemblies having a gas inlet and/or a gas outlet are disclosed.

Abstract: Biological fluid processing assemblies having a gas inlet and/or a gas outlet are disclosed.

Abstract: A connector assembly includes first and second fittings including first and second membrane assemblies, respectively, and a stem member. A fluid delivery system includes a connector assembly, a container for holding fluids and tubing which couples the container to one of the first and second fittings. A method for making a contaminant-free connection comprises mating first and second fittings, and establishing a fluid flow path through the first and second fittings. The systems, assemblies and methods according to the invention may be used, for example, to handle a biological fluid while maintaining the fluid free of viable contaminating microorganisms or preserving its sterility.