Abstract: A method of making a sterile connection comprises mating a first fitting having an aperture and a second fitting having an aperture, removing first and second strip out layers from between the end surfaces of sealed first and second resilient sealing members, and contacting the end surfaces of the resilient sealing members to provide fluid communication between the aperture of the first fitting and the aperture of the second fitting. A connector assembly comprises first and second fittings, a stem mounted for axial movement through the first fitting into the second fitting, and a deformable locking device which selectively prevents axial movement of the stem in the first fitting.

Abstract: A connector assembly and a fluid system or device comprises a connector assembly which includes first and second fittings, each fitting having an aperture, a first cap, and a stem disposed in the aperture of the first fitting. In various embodiments of the invention, the connector assembly further comprises a socket cooperatively arranged with one of the first and second fittings and at least one resilient sealing member. A method for making a connection includes removing a cap, mating first and second fittings, removing a stripout layer, and establishing a fluid flowpath through the first and second fittings.

Abstract: A connector or a connector assembly comprises a fitting, a resilient sealing member, a plurality of protrusions, and a removable stripout layer. The fitting includes a socket. The protrusions extend from the fitting and are connectable to a mating connector. The resilient sealing layer, which is disposed in the socket of the fitting, includes a hollow body having opposite open ends and an internal passage extending between the open ends. The removable stripout layer is movable between a first position in which the stripout layer overlies an end of the resilient sealing member and a second position in which the stripout layer is removed from the end of the resilient sealing member.

Abstract: Venting means for venting gas from the transfer line of a liquid delivery system comprising a housing, a first, liquid-wettable, microporous membrane carried in said housing so as to be in communication with the transfer line, a second, non-liquid-wettable, gas permeable microporous membrane superimposed on said microporous membrane to the outward side of the housing. Gas in the delivery system is vented from the system so long as the first microporous membrane remains unwetted by the delivery liquid.