Patents by Inventor Vladyslava Kovalska

Vladyslava Kovalska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210009809
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.
    Type: Application
    Filed: August 6, 2020
    Publication date: January 14, 2021
    Applicant: Enzo Life Sciences, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlam, Anatoliy Balanda, Dee Shen
  • Publication number: 20180273759
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.
    Type: Application
    Filed: April 26, 2018
    Publication date: September 27, 2018
    Applicant: Enzo Life Sciences, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlam, Anatoliy Balanda, Dee Shen
  • Patent number: 9932479
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: April 3, 2018
    Assignee: Enzo Biochem, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlum, Anatoliy Balanda
  • Publication number: 20160280921
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.
    Type: Application
    Filed: May 17, 2016
    Publication date: September 29, 2016
    Applicant: Enzo Life Sciences, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlum, Anatoliy Balanda, Dee Shen
  • Publication number: 20150376411
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
    Type: Application
    Filed: July 29, 2015
    Publication date: December 31, 2015
    Applicant: Enzo Biochem, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlum, Anatoliy Balanda
  • Patent number: 9133343
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
    Type: Grant
    Filed: November 30, 2009
    Date of Patent: September 15, 2015
    Assignee: Enzo Biochem, Inc.
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlam, Anatoliy Balanda
  • Publication number: 20130137112
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, and analysis of molecular chaperone activity.
    Type: Application
    Filed: November 30, 2010
    Publication date: May 30, 2013
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlam, Anatoliy Balanda, Dee Shen
  • Publication number: 20110130305
    Abstract: Provided are dyes and compositions which are useful in a number of applications, such as the detection and monitoring protein aggregation, kinetic studies of protein aggregation, neurofibrillary plaques analysis, evaluation of protein formulation stability, protein thermal stability shift assay and analysis of molecular chaperone activity. These dyes and compositions are also useful as probes in nucleic acid and protein detection.
    Type: Application
    Filed: November 30, 2009
    Publication date: June 2, 2011
    Inventors: Wayne Forrest Patton, Sergiy M. Yarmoluk, Praveen Pande, Vladyslava Kovalska, Lijun Dai, Kateryna Volkova, Jack Coleman, Mykhaylo Losytskyy, Anthony Ludlum, Anatoliy Balanda
  • Publication number: 20100041045
    Abstract: The present invention provides fluorescent dye compounds and methods of using the compounds for the staining of nucleic acids including qPCR applications. In particular, the dye compounds comprise heterocyclic molecules with hydroxy alkyl and aromatic substituents, and the dye compounds form highly fluorescent complexes upon nucleic acid binding.
    Type: Application
    Filed: July 14, 2009
    Publication date: February 18, 2010
    Applicant: SIGMA-ALDRICH CO.
    Inventors: Alexander Rueck, Bernhard Schoenenberger, Sergiy Yarmoluk, Vladyslava Kovalska, Mykhaylo Losytskyy, Yurii Slominskii
  • Publication number: 20080091015
    Abstract: Squaraine dyes are incorporated into a separation medium in which protein or polypeptide mixtures are separated, which medium also contains a detergent that forms a complex with the polypeptides or proteins. The dyes, upon excitation in the separation medium, exhibit a heretofore unrecognized selectivity in their fluorescent emissions by emitting a signal only when the dye molecules are associated with complexes of protein (or polypeptide) and detergent molecules, despite the additional presence of dyes in the bulk of the separation medium. The dyes are thus able to indicate the presence and locations of proteins or polypeptides in the separation medium without the need for removing unassociated dyes from the medium.
    Type: Application
    Filed: August 21, 2007
    Publication date: April 17, 2008
    Applicant: Bio-Rad Laboratories, Inc.
    Inventors: Thomas Berkelman, Sergiy Yarmoluk, Vladyslava Kovalska, Mykhaylo Losytskyy, Kateryna Volkova
  • Publication number: 20060207881
    Abstract: The present invention is generally directed to a method for detecting polyamino acids. More specifically, the present invention is directed to a method for detecting polyamino acids using trimethincyanine dyes that interact non-covalently with polyamino acids to produce an optically detectable dye/polyamino acid complex.
    Type: Application
    Filed: February 1, 2006
    Publication date: September 21, 2006
    Applicant: Sigma-Aldrich Co.
    Inventors: Vladyslava Kovalska, Dmytro Kryvorotenko, Mykhaylo Losytskyy, Pierre Nording, Alexander Rueck, Bernhard Schoenenberger, Sergiy Yarmoluk, Fabian Wahl