Patents by Inventor Vlastimil Hruska

Vlastimil Hruska has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chromatographic system and method of isolating compound in sample using chromatographic system
    Patent number: 9465016
    Abstract: A method is provided for isolating a compound in a sample by chromatography. The method includes determining an analytical gradient of an analytical system; performing an analytical run using the analytical gradient; identifying a target compound in the sample and determining an analytical retention time of the target compound using chromatographic results of the analytical run; determining an elution point of the target compound using the analytical retention time, the analytical gradient and characteristics of the analytical system; determining automatically a focusing gradient of a preparative system, including a slope segment; and performing a preparative run using the focusing gradient to separate the target compound from the sample. The slope segment includes a slope determining a concentration of solvent in a solvent mixture, which linearly increases from a first offset below the elution point of the target compound to a second offset above the elution point of the target compound.
    Type: Grant
    Filed: January 14, 2014
    Date of Patent: October 11, 2016
    Assignee: Agilent Technologies, Inc.
    Inventors: Frank Wolf, Vlastimil Hruska, Andreas Tei, Manuel Renz
  • CHROMATOGRAPHIC SYSTEM AND METHOD OF ISOLATING COMPOUND IN SAMPLE USING CHROMATOGRAPHIC SYSTEM
    Publication number: 20150198572
    Abstract: A method is provided for isolating a compound in a sample by chromatography. The method includes determining an analytical gradient of an analytical system; performing an analytical run using the analytical gradient; identifying a target compound in the sample and determining an analytical retention time of the target compound using chromatographic results of the analytical run; determining an elution point of the target compound using the analytical retention time, the analytical gradient and characteristics of the analytical system; determining automatically a focusing gradient of a preparative system, including a slope segment; and performing a preparative run using the focusing gradient to separate the target compound from the sample. The slope segment includes a slope determining a concentration of solvent in a solvent mixture, which linearly increases from a first offset below the elution point of the target compound to a second offset above the elution point of the target compound.
    Type: Application
    Filed: January 14, 2014
    Publication date: July 16, 2015
    Applicant: Agilent Technologies, Inc.
    Inventors: Frank Wolf, Vlastimil Hruska, Andreas Tei, Manuel Renz