Abstract: Apparatus, method, and software for electrocardiogram-assisted non-invasive arterial blood pressure d stiffness measurement is disclosed including brachial cuff with flexible electrodes, control box with rigid electrodes, and associated hardware/software. Cuff is wrapped around upper arm while electrodes on device are touched with fingers of other hand. Device acquires simultaneous ECG/oscillometric data during cuff deflation. Processing unit determines ECG R-peak positions to isolate arterial pulses and calculate pulse transit time. Change in pulse amplitude as function of cuff pressure is used for constructing oscillometric envelope and calculating blood pressure using empirical coefficients. Change in pulse transit time as function of cuff pressure is used independently for constructing pulse transit time envelopes and finding blood pressure with/without empirical coefficients. Fusion algorithm combines results for robust blood pressure and vessel stiffness evaluation.