Patents by Inventor VOLKER BOTTGER

VOLKER BOTTGER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of the Interaction between p53 and MDM2
    Publication number: 20050137137
    Abstract: The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounds, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild type p53 suppressor by interfering with the interaction between human p53 and human MDM2.
    Type: Application
    Filed: August 25, 2004
    Publication date: June 23, 2005
    Inventors: David Lane, Volker Bottger, Angelika Bottger, Steven Picksley, Heinz-Kurt Hochkeppel, Carlos Garcia-Echeverria, Patrick Chene, Pascal Furet
  • Method of producing recombinant antibodies
    Publication number: 20040219633
    Abstract: The invention relates to novel nucleic acid sequences which encode an antibody suitable in the field of tumor diagnostics and therapeutics. Further, a method of producing recombinant antibodies is provided, wherein the novel nucleic acid sequencs are employed.
    Type: Application
    Filed: August 7, 2003
    Publication date: November 4, 2004
    Applicant: WILEX AG
    Inventors: Reinier Lh Bolhuis, Thorsten Wohl, Volker Bottger
  • INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2
    Publication number: 20010018511
    Abstract: The present invention relates to compounds capable of binding to the oncogene protein MDM2, processes for the preparation of such compounds, pharmaceutical preparations comprising such compounsa, and uses of said compounds, e.g. in the therapeutic (including prophylactic) treatment of an animal or especially of the human body. The present further relates to methods of and compounds for inhibiting the growth of tumor cells which comprise the wild typr p53 suppressor by interfering with the interaction between human p53 and human MDM2.
    Type: Application
    Filed: March 26, 1999
    Publication date: August 30, 2001
    Inventors: DAVID LANE, VOLKER BOTTGER, ANGELIKA BOTTGER, STEVEN MICHAEL PICKSLEY, HEINZ-KURT HOCHKEPPEL, CARLOS GARCIA-ECHEVERRIA, PATRICK CHENE, PASCAL FURET