Abstract: A prediction algorithm determines synthetic fluorescence images on the basis of measurement images. A validation of the synthetic fluorescence images can be effected on the basis of reference images which are captured after the measurement images or are captured for a separate sample. Alternatively or additionally, a training of the prediction algorithm can be effected on the basis of training images which are captured after the measurement images or are captured for a separate sample.

Abstract: A prediction algorithm determines synthetic fluorescence images on the basis of measurement images. A validation of the synthetic fluorescence images can be effected on the basis of reference images which are captured after the measurement images or are captured for a separate sample. Alternatively or additionally, a training of the prediction algorithm can be effected on the basis of training images which are captured after the measurement images or are captured for a separate sample.

Abstract: A method and a microscope determine flow properties in a sample chamber through which a medium flows. The method includes detecting detection radiation from a confocal volume generated in the sample chamber with a plurality of detector elements of a detector in the form of a detector array at a plurality of points in time. The detector is arranged in a plane conjugate to the rear-side image plane of an objective. The measurement values from the detector elements can be analyzed individually. Cross correlations of the acquired measurement values from the detector elements of at least one pair are generated in two directions and analyzed. The confocal volume is generated at at least two mutually different locations of the sample chamber. At each location, a speed and optionally a movement direction of the medium are determined to create a flow profile over at least one region of the sample chamber.

Abstract: A method for training a machine learning system having a processing model for a sample type, which processes microscope images of samples of the sample type by virtual processing mapping, comprising recording at least one fine stack of a sample of the sample type, wherein the at least one fine stack comprises microscope images of the sample registered with respect to one another, determining at least one target microscope image based on the fine stack and the virtual processing mapping, creating an annotated data set comprising at least the target microscope image and a learning microscope image, wherein the learning microscope image is based on a coarse stack capturing the sample coarser than the fine stack, optimizing the processing model on the basis of the annotated data set.

Abstract: A reference sample for calibrating and/or adjusting a microscope and to uses of the reference sample. The latter has at least one carrier structure made of a carrier material which, at least in regions of its extent, is excitable to emit luminescence light, and at least one two-dimensional and/or three-dimensional structure consisting of a number of substructures. The carrier material is diamond or silicon carbide and is doped in or around the regions of the two-dimensional and/or three-dimensional structure in order to be excitable to emit the luminescence light.

Abstract: A prediction algorithm determines synthetic fluorescence images on the basis of measurement images. A validation of the synthetic fluorescence images can be effected on the basis of reference images which are captured after the measurement images or are captured for a separate sample. Alternatively or additionally, a training of the prediction algorithm can be effected on the basis of training images which are captured after the measurement images or are captured for a separate sample.

Abstract: The invention concerns a method for producing a cyclic L-amino acid of formula (I), characterised in that it consists in reacting a L-diamino acid of formula (II) or an enantiomeric mixture comprising such a L-diamino acid and a corresponding D-diamino acid in variable proportions, in the presence of an ornithine cyclodeaminase or a polypeptide homologous to the ornithine cyclodeaminase.

Abstract: In an exhaust gas turbine for a turbocharger of an internal combustion engine, including a housing with an inlet passage for conducting exhaust gas onto a turbine wheel supported in the housing, a guide vane structure movable into, and out of, an annular space of the inlet passage around the turbine wheel, an operating mechanism for moving the guide vane structure is provided which includes a cylinder, a ring provided with axial passages disposed around an inner sleeve, the guide vane structure being connected to one end of claws movably disposed in the axial passages and at least one of the claws being connected at its other end to the operating mechanism.

Abstract: In an exhaust gas turbine for a turbocharger of an internal combustion engine with a casing and a rotor rotatably supported in the casing, the casing includes an inlet duct with a guide vane structure supported so as to be movable into and out of a flow inlet area to the rotor by means of an electric motor.

Abstract: An exhaust-gas turbine for a turbocharger includes a rotor mounted rotatably in a turbine casing having a spiral inlet duct which is followed by an annular space surrounding the rotor. A guide-blade cascade is capable of being pushed axially into the annular space near the outer circumference of the rotor. The guide-blade cascade includes guide blades, is guided in an annular gap between an inner part and the turbine casing and is axially displaceable via an axial slide by a sliding sleeve. The guide-blade cascade with the axial slide, the inner part and/or the sliding sleeve are produced from an austenitic cast steel material having the following components: C≦0.2%; Si 1.5-2.5%; Mn≦2.00%; P≦0.045%; S≦0.03%; Cr 24.0-26.0%; Ni 19-22%; and W≦5%.

Abstract: In an exhaust turbine for a turbocharger having a rotor rotatably supported in a turbine casing wherein the turbine casing has a spiral inlet with an annular space disposed directly around the rotor and an axial cavity extending from the annular space axially into the casing and slideably receiving a guide vane structure so as to be movable between a retracted position in the annular space and an extended position, in which the guide vane structure is disposed in the annular space, the guide vane structure has opposite outer and inner cover rings and the turbine casing has a recess opposite the axial cavity so that in the extended position of the guide vane structure its outer cover ring is fittingly received in the recess while the inner cover ring is disposed at the outer end of the axial cavity providing for a smooth inlet flow duct surface.