Patents by Inventor Volker Germaschewski

Volker Germaschewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies Against Amyloid-Beta Peptide
    Publication number: 20110142824
    Abstract: Antibodies that bind human ?-amyloid peptide, methods of treating diseases or disorders characterised by elevated ?-amyloid levels or ?-amyloid deposits with said antibodies, pharmaceutical compositions comprising said antibodies and methods of manufacture.
    Type: Application
    Filed: March 27, 2007
    Publication date: June 16, 2011
    Applicant: GLAXO GROUP LIMITED
    Inventors: Stephan Anthony Burbidge, Jonathan Henry Ellis, Susannah K Ford, Volker Germaschewski, Umesh Kumar, Karen Louise Phillpott, Peter Ernest Soden
  • ANTIGEN BINDING PROTEINS
    Publication number: 20110064740
    Abstract: The present invention relates to methods of treating diseases or disorders affecting the eye or optic nerve characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly age related macular degeneration and glaucoma type diseases and ?-amyloid dependent cataract formation, with antigen binding proteins that bind ?-amyloid peptide and in particular human ?-amyloid peptide.
    Type: Application
    Filed: September 23, 2008
    Publication date: March 17, 2011
    Inventors: Stephen Anthony Burbidge, Ian Richard Catchpole, Jonathan Henry Ellis, Susannah Karen Ford, Volker Germaschewski, Umesh Kumar, Karen Louise Philpott, Peter Ernest Soden
  • ANTIGEN BINDING PROTEINS
    Publication number: 20110014182
    Abstract: Antigen binding proteins that bind ?-amyloid peptide, in particular human ?-amyloid peptide; methods of treating diseases or disorders characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated ?-amyloid levels or ?-amyloid deposits, including age related macular degeneration and glaucoma type diseases and ?-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture.
    Type: Application
    Filed: December 9, 2008
    Publication date: January 20, 2011
    Inventors: Philippe Marc Louis Alard, Ian Richard Catchpole, Jonathan Henry Ellis, Susannah Karen Ford, Gerald Wayne Gough, Volker Germaschewski, Alan Peter Lewis, Peter Ernest Soden, Pamela Joan Thomas, Trevor Anthony Kenneth Wattam
  • Immunoglobulins
    Patent number: 7858753
    Abstract: The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. In typical embodiments, OSM is glycosylated. The invention also concerns antibodies that modulate the interaction between both Site II and Site III of OSM and their respective interacting partners. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Grant
    Filed: March 29, 2005
    Date of Patent: December 28, 2010
    Assignee: Glaxo Group Limited
    Inventors: Jonathan Henry Ellis, Alexandre Eon-Duval, Volker Germaschewski, Christopher Plumpton, Nicholas Timothy Rapson, Michael Robert West
  • IMMUNOGLOBULINS
    Publication number: 20100221260
    Abstract: The present invention relates to antibodies to NOGO, pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorder.
    Type: Application
    Filed: December 14, 2006
    Publication date: September 2, 2010
    Inventors: Stephanie Jane Clegg, Jonathan Henry Ellis, Volker Germaschewski, Paul Andrew Hamblin, George Kopsidas, Ruth McAdam, Rabinder Kumar Prinjha
  • Humanised anti-mag antibody or functional fragment thereof
    Patent number: 7612183
    Abstract: The present invention relates to altered antibodies to myelin associated glycoprotein (MAG), pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorders.
    Type: Grant
    Filed: August 5, 2003
    Date of Patent: November 3, 2009
    Assignee: Glaxo Group Limited
    Inventors: Jonathan Henry Ellis, Volker Germaschewski
  • ANTIGEN BINDING PROTEINS
    Publication number: 20090162358
    Abstract: Antigen binding proteins that bind ?-amyloid peptide, in particular human ?-amyloid peptide; methods of treating diseases or disorders characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly Alzheimer's disease and diseases or disorders affecting the eye or optic nerve characterised by elevated ?-amyloid levels or ?-amyloid deposits, including age related macular degeneration and glaucoma type diseases and ?-amyloid dependent cataract formation, with said antigen binding proteins; pharmaceutical compositions comprising said antigen binding proteins; and methods of manufacture.
    Type: Application
    Filed: December 9, 2008
    Publication date: June 25, 2009
    Inventors: Philippe Marc Louis Alard, Jonathan Henry Ellis, Susannah Karen Ford, Volker Germaschewski, Alan Peter Lewis, Peter Ernest Soden, Pamela Joan Thomas, Trevor Anthony Kenneth Wattam
  • Humanised Anti-MAG Antibody or Functional Fragment Thereof
    Publication number: 20090053214
    Abstract: The present invention relates to altered antibodies to myelin associated glycoprotein (MAG), pharmaceutical formulations containing them and to the use of such antibodies in the treatment and/or prophylaxis of neurological diseases/disorders.
    Type: Application
    Filed: April 1, 2008
    Publication date: February 26, 2009
    Inventors: Jonathan Henry Ellis, Volker Germaschewski
  • NOVEL COMPOUNDS
    Publication number: 20080262203
    Abstract: The present invention relates to an antibody which has multiple specificities. In particular the antibody of the present invention binds to (cross react with) human IL-8, Gro-alpha, Gro-beta, Gro-gamma, and ENA-78.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 23, 2008
    Inventors: Stephanie Jane Clegg, Eric Dobrzynski, Jonathan H. Ellis, Volker Germaschewski, Alexis Paul Godillot, Zdenka Ludmila Jonak, Alan P. Lewis, John R. White
  • IMMUNOGLOBULINS
    Publication number: 20070292432
    Abstract: The present invention discloses humanised anti-IL-18 antibodies, methods of manufacture, and methods of treatment with said antibodies. Further disclosed are screening methods using for example surface plasmon resonance to identify antibodies with therapeutic potential.
    Type: Application
    Filed: May 23, 2007
    Publication date: December 20, 2007
    Inventors: Jonathan ELLIS, Volker Germaschewski, Paul Hamblin, Ian Kirby
  • Immunoglobulins
    Publication number: 20070286861
    Abstract: The present invention concerns immunoglobulins, such as antibodies, which specifically bind Oncostatin M (OSM), particularly human OSM (hOSM) and modulate the interaction between OSM and gp130. In typical embodiments, OSM is glycosylated. The invention also concerns antibodies that modulate the interaction between both Site II and Site III of OSM and their respective interacting partners. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
    Type: Application
    Filed: March 29, 2005
    Publication date: December 13, 2007
    Inventors: Jonathan Ellis, Alexandre Eon-Duval, Volker Germaschewski, Christopher Plumpton, Nicholas Rapson, Michael West
  • Antibodies
    Publication number: 20060165681
    Abstract: Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a selected hydroxy-1-azobenzene derivative.
    Type: Application
    Filed: August 5, 2003
    Publication date: July 27, 2006
    Inventors: Jonathan Ellis, Volker Germaschewski