Patents by Inventor Volker Klemt

Volker Klemt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analytical sandwich test for determining NT-proBNP
    Patent number: 9140709
    Abstract: The present invention concerns an immunological test for determining NT-proBNP comprising at least two antibodies to NT-proBNP, wherein at least one of the antibodies to NT-proBNP is a monoclonal antibody. The epitopes recognized by the antibodies can slightly overlap.
    Type: Grant
    Filed: January 15, 2009
    Date of Patent: September 22, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Juergen Spinke, Alfons Nichtl, Volker Klemt, Klaus Hallermayer, Michael Grol, Anneliese Borgya, Andreas Gallusser
  • MEASUREMENT OF C-TERMINAL proSP-B
    Publication number: 20140017815
    Abstract: In vitro methods for obtaining an indication of damage in the broncheoalveolar compartment of the lung comprising, measuring C-terminal proSP-B in a bodily fluid sample and comparing the level measured to a reference level of C-terminal proSP-B, wherein an increased level of C-terminal proSP-B is indicative of damage in the broncheoalveolar compartment of the lung.
    Type: Application
    Filed: September 20, 2013
    Publication date: January 16, 2014
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Volker Klemt, Christine Boehm, Andreas Gallusser, Ralf Roeddiger
  • Method of detecting a subfraction of proBNP
    Patent number: 7811770
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: October 12, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting a subfraction of proBNP
    Patent number: 7807380
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: October 5, 2010
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Analytical Sandwich Test for determining NT-proBNP
    Publication number: 20090123947
    Abstract: The present invention concerns an immunological test for determining NT-proBNP comprising at least two antibodies to NT-proBNP, wherein at least one of the antibodies to NT-proBNP is a monoclonal antibody. The epitopes recognized by the antibodies can slightly overlap.
    Type: Application
    Filed: January 15, 2009
    Publication date: May 14, 2009
    Inventors: Juergen Spinke, Alfons Nichtl, Volker Klemt, Klaus Hallermayer, Michael Grol, Anneliese Borgya, Andreas Gallusser
  • Analytical sandwich test for determining NT-proBNP
    Patent number: 7507550
    Abstract: The present invention concerns an immunological test for determining NT-proBNP comprising at least two antibodies to NT-proBNP, wherein at least one of the antibodies to NT-proBNP is a monoclonal antibody. One of these antibodies is directed at least against parts of the epitope of NT-proBNP comprising the amino acids 38 to 50. In addition, one of these antibodies is directed at least against parts of the epitope of NT-proBNP comprising the amino acids 1 to 37 or 43 to 76. The epitope recognized by the antibodies can slightly overlap.
    Type: Grant
    Filed: November 22, 2004
    Date of Patent: March 24, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Juergen Spinke, Alfons Nichtl, Volker Klemt, Klaus Hallermayer, Michael Grol, Anneliese Borgya, Andreas Gallusser
  • Method of detecting native proBNP
    Patent number: 7264939
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: September 4, 2007
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting native proBNP
    Patent number: 7264938
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: September 4, 2007
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting native proBNP
    Publication number: 20070117156
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Application
    Filed: December 22, 2006
    Publication date: May 24, 2007
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting a subfraction of proBNP
    Publication number: 20070099241
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Application
    Filed: December 5, 2006
    Publication date: May 3, 2007
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting native proBNP
    Publication number: 20060110775
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Application
    Filed: November 10, 2005
    Publication date: May 25, 2006
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Method of detecting native proBNP
    Publication number: 20060110776
    Abstract: The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a hybridoma cell line producing an antibody to native proBNP.
    Type: Application
    Filed: November 10, 2005
    Publication date: May 25, 2006
    Inventors: Anneliese Borgya, Andreas Gallusser, Michael Grol, Klaus Hallermayer, Volker Klemt, Christoph Seidel
  • Analytical sandwich test for determining NT-proBNP
    Publication number: 20050118662
    Abstract: The present invention concerns an immunological test for determining NT-proBNP comprising at least two antibodies to NT-proBNP, wherein at least one of the antibodies to NT-proBNP is a monoclonal antibody. One of these antibodies is directed at least against parts of the epitope of NT-proBNP comprising the amino acids 38 to 50. In addition, one of these antibodies is directed at least against parts of the epitope of NT-proBNP comprising the amino acids 1 to 37 or 43 to 76. The epitope recognized by the antibodies can slightly overlap.
    Type: Application
    Filed: November 22, 2004
    Publication date: June 2, 2005
    Inventors: Juergen Spinke, Alfons Nichtl, Volker Klemt, Klaus Hallermayer, Michael Grol, Anneliese Borgya, Andreas Gallusser
  • Antibody class-specific interference eliminating reagent
    Patent number: 5965378
    Abstract: The invention concerns a composition composed of several different antibodies or/and antibody fragments which is suitable as a reagent to reduce interferences in an immunological method for the class-specific detection of antibodies from one or several of the immunoglobulin classes G, M, A, D and E.
    Type: Grant
    Filed: April 24, 1997
    Date of Patent: October 12, 1999
    Assignee: Roche Diagnostics GmbH
    Inventors: Dittmar Schlieper, Helmut Lenz, Urban Schmitt, Volker Klemt
  • Elimination of rheumatoid factor interference using anti-FD antibodies
    Patent number: 5804391
    Abstract: The invention concerns the use of a composition which is composed of several different antibodies or/and antibody fragments which serves as a reagent to eliminate rheumatoid factor interference in an immunochemical method.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: September 8, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Volker Klemt, Dittmar Schlieper, Urban Schmitt, Michael Wiedmann
  • Electrochemiluminesence assay
    Patent number: 5723342
    Abstract: Method for measuring electrochemiluminescent phenomena at low temperatures using alkali chlorides at an increased pH and/or with a reduced initial voltage and reagents and apparatus suitable for this purpose.
    Type: Grant
    Filed: July 11, 1996
    Date of Patent: March 3, 1998
    Assignee: Boehringer Mannheim GmbH
    Inventors: Ursula Giesen, Nicholas Hoyle, Volker Klemt, Gunter Muller, Ulrich Neumann
  • Electrochemiluminescence assay
    Patent number: 5677192
    Abstract: Method for measuring electrochemiluminescent phenomena using certain detergents and, if necessary, alkali chlorides and reagents suitable for this purpose.
    Type: Grant
    Filed: March 18, 1996
    Date of Patent: October 14, 1997
    Assignee: Boehringer Mannheim GmbH
    Inventors: Volker Klemt, Gunter Muller, Ulrich Neumann, Ursula Giesen, Nicholas Hoyle