Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.

Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.

Abstract: A method of evaluating suitability of lighting conditions for detecting an analyte in a sample using a mobile device camera. A test strip is provided for detecting the analyte. A first image of the test strip is captured while an illumination source of the mobile device is turned off and a second image of the test strip is captured while the illumination source is turned on. A sample is applied to the test strip and the first and second images are compared to thereby determine the difference in lighting conditions between the first image and the second image. The comparison is used to derive information on suitability of the lighting conditions for analyte detection. The lighting conditions are indicated as suitable when a predetermined threshold amount of light intensity used for illumination of the test strip originates from the illumination source.

Abstract: A method of evaluating suitability of lighting conditions for detecting an analyte in a sample using a mobile device camera. A test strip is provided for detecting the analyte. A first image of the test strip is captured while an illumination source of the mobile device is turned off and a second image of the test strip is captured while the illumination source is turned on. A sample is applied to the test strip and the first and second images are compared to thereby determine the difference in lighting conditions between the first image and the second image. The comparison is used to derive information on suitability of the lighting conditions for analyte detection. The lighting conditions are indicated as suitable when a predetermined threshold amount of light intensity used for illumination of the test strip originates from the illumination source.

Abstract: A method of determining the concentration of an analyte in a sample of a body fluid with a mobile device having a camera is disclosed. The camera captures an image of a color reference card and of a reagent test field of an optical test strip having a sample applied to it. A predetermined pixel-based mean tone map correction is applied to the image obtained, which results in a first intensity-corrected image. Local brightness information is derived from the first intensity-corrected image. A mobile device-specific tone map correction is applied to the first intensity-corrected image, taking into account the local brightness information. A second intensity-corrected image is thereby obtained. Analyte concentration is determined based on a color formation reaction of the test field by using the second intensity-corrected image. Optionally, a color correction may be derived and applied to the second intensity-corrected image to obtain an intensity-corrected and color-corrected image.

Abstract: A method of evaluating the quality of a color reference card having multiple color reference fields. The quality refers to whether the color reference card is usable for a method for determining concentration of analyte in a body fluid and/or to the degree of suitability or reliability of the color reference card for use with a method for determining analyte concentration in a body fluid. In the inventive method, an image is captured of at least a part of the color reference card using a mobile device camera. Measured color reference values are determined from the image for one or more of the color reference fields and a relationship between one or more of the measured reference color values and corresponding known reference color values is determined. The determined relationship is used to assess the quality of the color reference card. A kit and mobile device are also disclosed.

Abstract: A method of determining concentration of an analyte in a body fluid using a mobile device having a camera is disclosed. In the inventive method, the camera is used to take a series of calibration images of a region of interest of an object. The calibration images differ in their brightness. A key calibration figure is derived from each calibration image, the key calibration images being characteristic for a tone mapping function of the mobile device. A probable tone mapping function of the mobile device is determined by taking into account the key calibration figures. An analysis image is taken of at least part of a test field of an optical test strip, the test field having a body fluid applied thereto. Analyte concentration is determined from the analysis image of the test field by taking into account the probable tone mapping function of the mobile device.

Abstract: An optical system (100) for a light emitting diode (LED) signal includes a plurality of light emitting diodes (LEDs) (12, 14), a plurality of optical lenses (20, 40, 60, 80) for diverging and collimating light generated by the plurality of LEDs (12, 14), wherein the plurality of LEDs (12, 14) and the plurality of optical lenses (20, 40, 60, 80) are sequentially arranged in an axial direction, and wherein the plurality of optical lenses (20, 40, 60, 80) are configured such that by altering an axial position of one of the optical lenses (20, 40, 60, 80) from a first defined axial position to a second defined axial position, a final angular light distribution of the optical system (100) is variable.

Abstract: An optical test strip (110), a method and a kit (128) for measuring an analyte concentration in a sample (112) of bodily fluid are disclosed.

Abstract: A method of determining analyte concentration in a body fluid with a mobile device having a camera. A user is prompted to apply body fluid to an optical test strip and then waits a predetermined minimum waiting time. The camera captures an image of part of the test field having the body fluid applied thereto. Analyte concentration is determined based on the image captured. The determination includes estimating a point in time of sample application to the test field by taking into account time-dependent information derived from the image captured using a first color channel of a color space. The determination also estimates the concentration of the analyte by taking into account concentration-dependent information derived from the image using a second color channel of the color space.

Abstract: A method for detecting an analyte in a sample is disclosed. The method includes providing a mobile device having a camera and an illumination source. A test strip having a test field with at least one test chemical for performing an optical detection reaction in the presence of the analyte is provided. The sample is applied to the test field. Several images of a region of the test strip are captured. The region includes at least part of the test field to which sample is applied. The images are captured before and after the sample is applied and with the illumination source turned on and off. The images captured are compared and differences in light intensities are determined. Analyte concentration is determined using the images captured and the determined light intensities.

Abstract: A method of evaluating suitability of lighting conditions for detecting an analyte in a sample using a mobile device camera. A test strip is provided for detecting the analyte. A first image of the test strip is captured while an illumination source of the mobile device is turned off and a second image of the test strip is captured while the illumination source is turned on. A sample is applied to the test strip and the first and second images are compared to thereby determine the difference in lighting conditions between the first image and the second image. The comparison is used to derive information on suitability of the lighting conditions for analyte detection. The lighting conditions are indicated as suitable when a predetermined threshold amount of light intensity used for illumination of the test strip originates from the illumination source.

Abstract: An optical system (100) for a light emitting diode (LED) signal includes a plurality of light emitting diodes (LEDs) (12, 14), a plurality of optical lenses (20, 40, 60, 80) for diverging and collimating light generated by the plurality of LEDs (12, 14), wherein the plurality of LEDs (12, 14) and the plurality of optical lenses (20, 40, 60, 80) are sequentially arranged in an axial direction, and wherein the plurality of optical lenses (20, 40, 60, 80) are configured such that by altering an axial position of one of the optical lenses (20, 40, 60, 80) from a first defined axial position to a second defined axial position, a final angular light distribution of the optical system (100) is variable.

Abstract: A display element and a display device in which the display element is mounted. The display may be a variable message sign. The sign includes a tube-like housing in which lenses and apertures can be disposed. The light exiting a light source is emitted via an emitting surface, by way of which an illuminated traffic sign results from interacting with further display elements. The light source and the optical elements are disposed at different heights in the horizontally oriented housing. The optical axes can thereby extend horizontally, or the optical elements can lie on a main axis which is tilted downward in an radiation direction. In both cases, sunlight impinging from above at an angle advantageously falls on the LED to a slight degree, by way of which the phantom light phenomenon is minimized.

Abstract: A display element and a display device in which the display element is mounted. The display may be a variable message sign. The sign includes a tube-like housing in which lenses and apertures can be disposed. The light exiting a light source is emitted via an emitting surface, by way of which an illuminated traffic sign results from interacting with further display elements. The light source and the optical elements are disposed at different heights in the horizontally oriented housing. The optical axes can thereby extend horizontally, or the optical elements can lie on a main axis which is tilted downward in an radiation direction. In both cases, sunlight impinging from above at an angle advantageously falls on the LED to a slight degree, by way of which the phantom light phenomenon is minimized.