Patents by Inventor Volker Unkrig

Volker Unkrig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10180420
    Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: January 15, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Klaus Andreas Bauer-Espindola, Carina Horn, Michael Marquant, Christine Nortmeyer, Volker Unkrig
  • Patent number: 9670524
    Abstract: Test elements are disclosed for detecting at least one analyte concentration in a sample. The test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of at least one diffusable label.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: June 6, 2017
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Carina Horn, Volker Unkrig
  • Publication number: 20160091482
    Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Inventors: Klaus Andreas Bauer-Espindola, Carina Horn, Michael Marquant, Christine Nortmeyer, Volker Unkrig
  • Publication number: 20160083777
    Abstract: Test elements are disclosed for detecting at least one analyte concentration in a sample. The test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of at least one diffusable label.
    Type: Application
    Filed: December 7, 2015
    Publication date: March 24, 2016
    Inventors: Carina Horn, Volker Unkrig
  • Patent number: 9255286
    Abstract: Methods are disclosed for detecting at least one analyte in a sample. The methods are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The methods correct for an interfering variable such as temperature and/or hematocrit in a test element system via a correction factor based upon diffusion of a diffusable label.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: February 9, 2016
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Carina Horn, Volker Unkrig
  • Publication number: 20140302541
    Abstract: Methods, devices and test elements are disclosed for detecting at least one analyte in a sample. The methods, devices and test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The methods, devices and test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of a diffusable label.
    Type: Application
    Filed: June 20, 2014
    Publication date: October 9, 2014
    Inventors: Carina Horn, Volker Unkrig
  • Patent number: 8409413
    Abstract: A device for sampling liquid samples is provided comprising a capillary-active channel, a sampling site, and a determination site. The capillary-active channel is configured for transporting a sample from the sampling site to the determination site. The capillary-active channel is substantially formed by a carrier, a cover and an intermediate layer located between the carrier and cover. The carrier protrudes beyond the cover in the area of the sampling site. The intermediate layer is displaced towards the back in the direction of the determination site in the area of the sampling site so that the carrier as well as the cover protrude beyond the intermediate layer. The device allows sample to be applied from above onto the exposed area of the carrier in the area of the sampling site and also allows sample to be applied from the side.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: April 2, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Volker Gerstle, Volker Unkrig, Manfred Augstein
  • Patent number: 8357274
    Abstract: An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: January 22, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Udo Zapf, Gregor Bainczyk, Volker Unkrig, Mihail-Onoriu Lungu, Holger Kotzan
  • Patent number: 8182747
    Abstract: The invention concerns a test device for analyzing especially a biological sample liquid comprising a composite body consisting of a plurality of layers of flat materials and a sample channel located in the composite body for transporting the sample liquid from an application site to a measuring site. According to the invention it is proposed that the composite body has a plurality of transport layers arranged in a stack-like manner between support layers for holding in each case sample channel.
    Type: Grant
    Filed: July 25, 2003
    Date of Patent: May 22, 2012
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Michael Marquant, Volker Unkrig, Fritz Hindelang
  • Patent number: 8137980
    Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: March 20, 2012
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
  • Publication number: 20110177605
    Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
    Type: Application
    Filed: February 22, 2011
    Publication date: July 21, 2011
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail-Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
  • Patent number: 7914752
    Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.
    Type: Grant
    Filed: October 12, 2004
    Date of Patent: March 29, 2011
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail-Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
  • Patent number: 7626401
    Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method discloses determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.
    Type: Grant
    Filed: August 7, 2008
    Date of Patent: December 1, 2009
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
  • Publication number: 20090027064
    Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method comprises determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.
    Type: Application
    Filed: August 7, 2008
    Publication date: January 29, 2009
    Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
  • Publication number: 20090020439
    Abstract: An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.
    Type: Application
    Filed: July 22, 2008
    Publication date: January 22, 2009
    Inventors: Michael Marquant, Udo Zapf, Gregor Bainczyk, Volker Unkrig, Mihail-Onoriu Lungu, Holger Kotzan
  • Patent number: 7429865
    Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method involves determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.
    Type: Grant
    Filed: October 4, 2006
    Date of Patent: September 30, 2008
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
  • Publication number: 20070102292
    Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method comprises determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.
    Type: Application
    Filed: October 4, 2006
    Publication date: May 10, 2007
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
  • Publication number: 20060035298
    Abstract: System and method for the determination of a coagulation parameter comprising a disposable test element and an instrument for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, the non-standard temperature being measured by a temperature measurement device of the instrument, the instrument has a non-volatile memory containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at the non-standard temperature, using the mathematical relationship.
    Type: Application
    Filed: August 3, 2005
    Publication date: February 16, 2006
    Inventors: James Hill, Volker Unkrig, Ewald Rieger
  • Publication number: 20050214171
    Abstract: A device for sampling liquid samples is provided comprising a capillary-active channel, a sampling site, and a determination site. The capillary-active channel is configured for transporting a sample from the sampling site to the determination site. The capillary-active channel is substantially formed by a carrier, a cover and an intermediate layer located between the carrier and cover. The carrier protrudes beyond the cover in the area of the sampling site. The intermediate layer is displaced towards the back in the direction of the determination site in the area of the sampling site so that the carrier as well as the cover protrude beyond the intermediate layer. The device allows sample to be applied from above onto the exposed area of the carrier in the area of the sampling site and also allows sample to be applied from the side.
    Type: Application
    Filed: May 2, 2003
    Publication date: September 29, 2005
    Inventors: Volker Gerstle, Volker Unkrig, Manfred Augstein
  • Publication number: 20050191431
    Abstract: The present invention is generally directed towards a method for producing an analytical test strip. More particularly to a method of producing a test strip having an insulating substrate provided with a layer electrode wherein the test strip has an increased hydrophilic property.
    Type: Application
    Filed: January 26, 2005
    Publication date: September 1, 2005
    Inventors: Carina Horn, Volker Unkrig, Christine Nortmeyer