Patents by Inventor Volker Unkrig
Volker Unkrig has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10180420Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.Type: GrantFiled: December 9, 2015Date of Patent: January 15, 2019Assignee: Roche Diagnostics Operations, Inc.Inventors: Klaus Andreas Bauer-Espindola, Carina Horn, Michael Marquant, Christine Nortmeyer, Volker Unkrig
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Patent number: 9670524Abstract: Test elements are disclosed for detecting at least one analyte concentration in a sample. The test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of at least one diffusable label.Type: GrantFiled: December 7, 2015Date of Patent: June 6, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Carina Horn, Volker Unkrig
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Publication number: 20160091482Abstract: A method for detecting at least one analyte in a body fluid is disclosed comprising performing an optical measurement, wherein at least one test chemical is contacts the body fluid. The test chemical is an optical test chemical adapted to perform at least one detection reaction, wherein at least one optically detectable property is changed due to the detection reaction to provide at least one optical measurement value. At least one impedance measurement is generated wherein at least one alternating electrical signal is applied to the body fluid via the impedance measurement electrodes and at least one answer signal is recorded, and at least one impedance measurement value is generated. At least one evaluation step is performed wherein at least one evaluation algorithm is used, and the optical measurement value and the impedance measurement value are used for determining a concentration of the analyte in the body fluid.Type: ApplicationFiled: December 9, 2015Publication date: March 31, 2016Inventors: Klaus Andreas Bauer-Espindola, Carina Horn, Michael Marquant, Christine Nortmeyer, Volker Unkrig
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Publication number: 20160083777Abstract: Test elements are disclosed for detecting at least one analyte concentration in a sample. The test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of at least one diffusable label.Type: ApplicationFiled: December 7, 2015Publication date: March 24, 2016Inventors: Carina Horn, Volker Unkrig
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Patent number: 9255286Abstract: Methods are disclosed for detecting at least one analyte in a sample. The methods are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The methods correct for an interfering variable such as temperature and/or hematocrit in a test element system via a correction factor based upon diffusion of a diffusable label.Type: GrantFiled: June 20, 2014Date of Patent: February 9, 2016Assignee: Roche Diabetes Care, Inc.Inventors: Carina Horn, Volker Unkrig
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Publication number: 20140302541Abstract: Methods, devices and test elements are disclosed for detecting at least one analyte in a sample. The methods, devices and test elements are used for detecting one or more analytes such as metabolites in body fluids, especially glucose. The methods, devices and test elements correct for an interfering variable such as temperature and or hematocrit in a test element system via a correction factor based upon diffusion of a diffusable label.Type: ApplicationFiled: June 20, 2014Publication date: October 9, 2014Inventors: Carina Horn, Volker Unkrig
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Patent number: 8409413Abstract: A device for sampling liquid samples is provided comprising a capillary-active channel, a sampling site, and a determination site. The capillary-active channel is configured for transporting a sample from the sampling site to the determination site. The capillary-active channel is substantially formed by a carrier, a cover and an intermediate layer located between the carrier and cover. The carrier protrudes beyond the cover in the area of the sampling site. The intermediate layer is displaced towards the back in the direction of the determination site in the area of the sampling site so that the carrier as well as the cover protrude beyond the intermediate layer. The device allows sample to be applied from above onto the exposed area of the carrier in the area of the sampling site and also allows sample to be applied from the side.Type: GrantFiled: May 2, 2003Date of Patent: April 2, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Volker Gerstle, Volker Unkrig, Manfred Augstein
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Patent number: 8357274Abstract: An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.Type: GrantFiled: July 22, 2008Date of Patent: January 22, 2013Assignee: Roche Diagnostics Operations, Inc.Inventors: Michael Marquant, Udo Zapf, Gregor Bainczyk, Volker Unkrig, Mihail-Onoriu Lungu, Holger Kotzan
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Patent number: 8182747Abstract: The invention concerns a test device for analyzing especially a biological sample liquid comprising a composite body consisting of a plurality of layers of flat materials and a sample channel located in the composite body for transporting the sample liquid from an application site to a measuring site. According to the invention it is proposed that the composite body has a plurality of transport layers arranged in a stack-like manner between support layers for holding in each case sample channel.Type: GrantFiled: July 25, 2003Date of Patent: May 22, 2012Assignee: Roche Diagnostics Operations, Inc.Inventors: Michael Marquant, Volker Unkrig, Fritz Hindelang
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Patent number: 8137980Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.Type: GrantFiled: February 22, 2011Date of Patent: March 20, 2012Assignee: Roche Diagnostics Operations, Inc.Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
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Publication number: 20110177605Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.Type: ApplicationFiled: February 22, 2011Publication date: July 21, 2011Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail-Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
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Patent number: 7914752Abstract: The invention concerns a reagent system for the so-called on-board control of analytical elements, in particular test strips, containing an organic N-oxide or a nitroso compound. The invention also concerns analytical elements containing a reagent system for a detection reaction and a reagent system for an on-board control. Furthermore, the invention concerns a method for checking analytical elements in which a reagent system for an on-board control is examined optically or electrochemically with the aid of a measuring instrument for changes which could indicate a stress of the analytical element.Type: GrantFiled: October 12, 2004Date of Patent: March 29, 2011Assignee: Roche Diagnostics Operations, Inc.Inventors: Volker Unkrig, Christine Nortmeyer, Carina Horn, Michael Marquant, Mihail-Onoriu Lungu, Joachim Hoenes, Holger Kotzan, Joerg Dreibholz
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Patent number: 7626401Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method discloses determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.Type: GrantFiled: August 7, 2008Date of Patent: December 1, 2009Assignee: Roche Diagnostics Operations, Inc.Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
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Publication number: 20090027064Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method comprises determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.Type: ApplicationFiled: August 7, 2008Publication date: January 29, 2009Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
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Publication number: 20090020439Abstract: An electrochemical biosensor analysis system is provided for analyzing a sample liquid, comprising a biosensor having an electrode structure made of at least two electrodes, a test field, covering the electrode structure and capable of absorbing the sample liquid, and a defined sample application surface on the top side of the test field. The system also includes an analysis instrument comprising an evaluation unit for determining the desired analysis data. The analysis instrument comprises an AC resistance measuring device for measuring an AC resistance value between two electrodes of the electrode structure by means of an area compensation measurement. The measured AC resistance value is used, in the determination of the analysis data, as a measure of the partial area of the effective electrode structure area wetted by the sample liquid.Type: ApplicationFiled: July 22, 2008Publication date: January 22, 2009Inventors: Michael Marquant, Udo Zapf, Gregor Bainczyk, Volker Unkrig, Mihail-Onoriu Lungu, Holger Kotzan
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Patent number: 7429865Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method involves determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.Type: GrantFiled: October 4, 2006Date of Patent: September 30, 2008Assignee: Roche Diagnostics Operations, Inc.Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
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Publication number: 20070102292Abstract: A method and a corresponding system for error checking an electrochemical sensor having at least two electrodes and a liquid measuring medium applied thereto are disclosed. The method comprises determining a first admittance between a first set of electrodes of the sensor; determining a second admittance between a second set of electrodes of the sensor; determining a value using the first admittance and the second admittance; and displaying an error message if the value is out of a predetermined tolerance.Type: ApplicationFiled: October 4, 2006Publication date: May 10, 2007Applicant: Roche Diagnostics Operations, Inc.Inventors: Joerg Dreibholz, Sylvia Saecker, Volker Unkrig
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Publication number: 20060035298Abstract: System and method for the determination of a coagulation parameter comprising a disposable test element and an instrument for evaluation thereof. The coagulation time is determined at a non-standard temperature different from a standard temperature for the respective coagulation parameter, the non-standard temperature being measured by a temperature measurement device of the instrument, the instrument has a non-volatile memory containing data which define a mathematical relationship of coagulation time versus temperature which relationship is independent of the individual patient whose blood is examined, and the coagulation parameter for the standard temperature is calculated from the coagulation time measured at the non-standard temperature, using the mathematical relationship.Type: ApplicationFiled: August 3, 2005Publication date: February 16, 2006Inventors: James Hill, Volker Unkrig, Ewald Rieger
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Publication number: 20050214171Abstract: A device for sampling liquid samples is provided comprising a capillary-active channel, a sampling site, and a determination site. The capillary-active channel is configured for transporting a sample from the sampling site to the determination site. The capillary-active channel is substantially formed by a carrier, a cover and an intermediate layer located between the carrier and cover. The carrier protrudes beyond the cover in the area of the sampling site. The intermediate layer is displaced towards the back in the direction of the determination site in the area of the sampling site so that the carrier as well as the cover protrude beyond the intermediate layer. The device allows sample to be applied from above onto the exposed area of the carrier in the area of the sampling site and also allows sample to be applied from the side.Type: ApplicationFiled: May 2, 2003Publication date: September 29, 2005Inventors: Volker Gerstle, Volker Unkrig, Manfred Augstein
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Publication number: 20050191431Abstract: The present invention is generally directed towards a method for producing an analytical test strip. More particularly to a method of producing a test strip having an insulating substrate provided with a layer electrode wherein the test strip has an increased hydrophilic property.Type: ApplicationFiled: January 26, 2005Publication date: September 1, 2005Inventors: Carina Horn, Volker Unkrig, Christine Nortmeyer