Patents by Inventor Volkert Claassen

Volkert Claassen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4196216
    Abstract: Certain nuclear substituted benzylidene amino oxyalkyl carboxylic acids esters, amides and salts thereof have been found to have a strong anti-inflammatory activity and a potent analgetic activity. In addition, some of the compounds have an activity against Rhino virus. An example is [(4-chlorobenzylideneamino)oxy] acetic acid.
    Type: Grant
    Filed: November 2, 1977
    Date of Patent: April 1, 1980
    Assignee: U.S. Philips Corporation
    Inventors: Jan Van Dijk, Volkert Claassen, Johannes M. A. Zwagemakers
  • Patent number: 4192893
    Abstract: The novel compounds of formula I and salts thereof have a very powerful anti-depressive activity which for a considerable part, and in some substances even entirely, is based on serotonine potentiation. Moncamino oxidase inhibition does not contribute to the anti-depressive effect. The substances are little toxic and substantially free from side effects.The compounds can be synthesized and processed to compositions according to known methods.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: March 11, 1980
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus B. A. Welle, Volkert Claassen
  • Patent number: 4086361
    Abstract: The compounds of the formula ##STR1## where Hal is Br or Cl and R is ethoxy, methoxymethyl, ethoxymethyl, cyano, methoxyethoxy or cyanomethyl when Hal is Cl and is cyano, methoxy or methoxyethoxy when Hal is Br and their salts have a strong anti-depressive activity resulting in a powerful potentiation of noradrenalin and in a strong serotonin potentiation. Monoamino oxidase inhibition does not provide a basis for the antidepressive activity of these compounds. The compounds are free from noxious side effects to a considerable extent, for example, broncho-constriction and stomach ulceration.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: April 25, 1978
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus Bernardus Antonius Welle, Volkert Claassen
  • Patent number: 4085225
    Abstract: Novel 4'-trifluoromethylvalerophenone 0-(2-aminoethyl)oximes are found to exhibit a strong anti-depressive activity based on a strong serotone potentiation but with the absence of monoamino/oxidase inhibition and undesirable side effects.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: April 18, 1978
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus Bernardus Antonius Welle, Volkert Claassen
  • Patent number: 4081551
    Abstract: A very powerful serotonine potentiation was found of oxime ethers of the formula ##STR1## where R is methoxy, ethoxy, cyano, cyanomethyl, chlorine, methoxyethoxy or methoxymethyl and their salts which is associated with a much less strong noradrenaline potentiation. The compounds have no anti-depressive activity component based on monoamino oxidase inhibition and are substantially free from side effects.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: March 28, 1978
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus Bernardus Antonius Welle, Volkert Claassen
  • Patent number: 4081552
    Abstract: Anti-depressive compounds of the formula ##STR1## wherein R is (CH.sub.2).sub.p CN, (CH.sub.2).sub.p O(CH.sub.2).sub.q CH.sub.3 or (CH.sub.2).sub.r O(CH.sub.2)OCH.sub.3 and p = 1, 2 or 3 q = 0 or 1 and r = 0, 1 or 2.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: March 28, 1978
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus Bernardus Antonius Welle, Volkert Claassen
  • Patent number: 4071686
    Abstract: Certain nuclear substituted benzylidene amino oxyalkyl carboxylic acids esters, amides and salts thereof have been found to have a strong anti-inflammatory activity and a potent analgetic activity. In addition, some of the compounds have an activity against Rhino virus. An example is [(4-chlorobenzylideneamino)oxy] acetic acid.
    Type: Grant
    Filed: December 17, 1976
    Date of Patent: January 31, 1978
    Assignee: U.S. Philips Corporation
    Inventors: Jan van Dijk, Volkert Claassen, Johannes Maria Antonius Zwagemakers
  • Patent number: 4060631
    Abstract: Compounds of the formula ##STR1## wherein R is alkyl of 4 to 6 carbons, benzyl, 4-ethoxybutyl, 5 ethoxypentyl, 4-cyanobutyl or 5-cyanopentyl exhibit strong serotonine potentiation with no monoamino oxidase inhibition and are substantially free of side effects.
    Type: Grant
    Filed: March 19, 1976
    Date of Patent: November 29, 1977
    Assignee: U.S. Philips Corporation
    Inventors: Hendricus Bernardus Antonius Welle, Volkert Claassen
  • Patent number: 3936491
    Abstract: Substituted diphenyl adamantylidene methanes. Examples of substituents on the para positions of the phenyl groups are propoxy and acetyloxy. The compounds have estrogenic activities.
    Type: Grant
    Filed: November 29, 1968
    Date of Patent: February 3, 1976
    Assignee: U.S. Philips Corporation
    Inventor: Volkert Claassen