Patents by Inventor Volkhard Austel

Volkhard Austel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4026891
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, trifluoromethyl, alkyl of 1 to 5 carbon atoms, mercapto, lower alkyl-mercapto, phenyl, fluoro-phenyl, tolyl, hydroxy-phenyl, methylmercapto-phenyl, methylsulfinyl-phenyl, methylsulfonyl-phenyl, dimethylamino-phenyl, or mono-, di- or tri-methoxy-substituted phenyl;A is hydrogen or, together with B, a double bond,B is hydrogen, alkyl of 1 to 3 carbon atoms or, together with A, a double bond;C is, together with R.sub.2, a double bond, or, together with R.sub.3, oxygen;R.sub.2 is hydrogen, alkyl of 1 to 3 carbon atoms or, together with C, a double bond; andR.sub.3 is chlorine, methylamino, morpholino, 4-methylpiperazino or, when R.sub.2 is hydrogen or alkyl of 1 to 3 carbon atoms, together with C, oxygen;And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as hypotensives, antithrombotics and cardiotonics.
    Type: Grant
    Filed: June 4, 1975
    Date of Patent: May 31, 1977
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Volkhard Austel, Eberhard Kutter, Joachim Heider, Wolfgang Eberlein, Rudolf Kadatz, Willi Diederen
  • Patent number: 3985891
    Abstract: Compounds of the isomeric formulas ##SPC1##WhereinR.sub.1 is alkoxy of 1 to 4 carbon atoms, allyloxy, benzyloxy, methoxy-ethoxy, methylthio, methylsulfinyl, methylsulfonyl or methylsulfinylethoxy,R.sub.2 is hydrogen, hydroxyl, methyl, methoxy, ethoxy, fluorine, chlorine, (alkyl of 1 to 4 carbon atoms)-thio, (alkyl of 1 to 4 carbon atoms)-sulfinyl, (alkyl of 1 to 4 carbon atoms)-sulfonyl, dimethylamino or Z-A-O-whereA is alkylene of 2 to 3 carbon atoms, andZ is chlorine, hydroxyl, methylthio, ethylthio, methylsulfinyl; ethylsulfinyl, methylsulfonyl, ethylsulfonyl, methylamino, dimethylamino, diethylamino, phenethylamino, N-methyl-phenethylamino or N-methyl-dimethoxyphenethylamino,R.sub.3 is hydrogen or methoxy,Or any two of R.sub.1, R.sub.2 and R.sub.3 together are methylenedioxy, andR.sub.5 is hydrogen, chlorine or methyl,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as cardiotonics, anticoagulants and for altering the blood pressure.
    Type: Grant
    Filed: August 22, 1975
    Date of Patent: October 12, 1976
    Assignee: Boehringer Ingelheim GmbH
    Inventors: Eberhard Kutter, Volkhard Austel, Willi Diederen