Abstract: The invention relates to a method for carrying out signal detection by means of magnetic particle imaging, in which method magnetic/magnetisable particles (4), arranged in the field-free region of a location-dependent magnetic field, in particular a gradient magnetic field, are magnetised by means of an excitation magnetic field that changes over time, and the harmonics (9, 15), generated by the particles (4), of the frequency of the excitation magnetic field are detected as a signal from the magnetic particles (4) by means of a receiver coil arrangement (1) which in particular surrounds the particles (4), wherein a signal-transmitting arrangement, which has an outer coil (10) and at least one inner coil (11; 16, 17) connected in series to said outer coil, is positioned within the receiver coil arrangement (1) around the particles (4), wherein the signal received from the particles (4) by the at least one inner coil (11; 16, 17) is transmitted to the outer coil (10) by current flow and is re-emitted by said o

Abstract: The invention relates to a therapy planning device for planning a therapy to be applied to tissue of a subject (2). A tissue parameter distribution, which has been generated based on a magnetic resonance fingerprint scan of the tissue, and a therapy goal distribution, which defines a distribution of at least one parameter being indicative of a desired effect of the therapy, are provided. A machine learning module (13), which has been trained to output at least one therapy application parameter defining the application of the therapy based on an input tissue parameter distribution and an input therapy goal distribution, is used for planning the therapy by determining the at least one therapy application parameter based on the provided tissue parameter distribution and the provided therapy goal distribution. This allows for a consideration of the actual quantitative tissue parameter distriution of the patient, thereby improving planning quality.

Abstract: The invention relates to a computer-controlled lighting system which comprises an interface for defining a work surface within the lighting system and a desired illumination of the work surface, at least one luminaire for illuminating the work surface and a processing unit for automatically computing configuration parameters which allow configuring the at least one luminaire such that the desired illumination of the work surface is achievable.

Abstract: The invention relates to a system for generating an estimate of a photon attenuation map for an object on the basis of single-scattered coincidences measured in a PET scanner. The system comprises a simulation module configured to calculate single-scattered coincidences by a numerical model calculation based on a preliminary attenuation map, where the estimate of the photon attenuation map is generated by adapting at least some attenuation values. The model calculation is made on the basis of a grid covering the object, the grid comprising grid elements (61) to which attenuation values are assigned, and the simulation module is further configured to determine at least one set of adjacent grid elements (61) in order to form a merged image element (63) including the set of adjacent grid elements (61) and to assign a single attenuation value to the merged image element in the model calculation.

Abstract: A lung segmentation processor (40) is configured to classify magnetic resonance (MR) images based on noise characteristics. The MR segmenatation processor generates a lung region of interest (ROI) and detailed structure segmentation of the lung from the ROI. The MR segmentation processor performs an iterative normalization and region definition approach that captures the entire lung and the soft tissues within the lung accurately. Accuracy of the segmentation relies on artifact classification coming inherently from MR images. The MR segmentation processor (40) correlates segmented lung internal tissue pixels with the lung density to determine the attenuation coefficients based on the correlation. Lung densities are computed using MR data obtained from imaging sequences that minimize echo and acquisition times. The densities differentiate healthy tissues and lesions, which an attenuation map processor (36) uses to create localized attenuation maps for the lung.

Abstract: A ready to use catheter assembly comprises a catheter package with an opening, a catheter with a shaft arranged in the catheter package so a distal end of the catheter lies in the region of the opening, and a protective sleeve which partly covers the catheter shaft, a first end of the protective sleeve fixed to the distal end of the catheter. A method for producing a ready to use catheter assembly and a ready to use catheter assembly which further reduces the risk of an accidental contamination of a catheter when pulling it out of the catheter package prior to the insertion into the urethra of a user are provided. The opening has a defined maximum opening length, a second end of the protective sleeve is releasably connected which the catheter package near the maximum opening length of the opening and the protective sleeve is in a retracted state.

Abstract: A combined PET/MR system includes an MR subsystem including a main field magnet (14) which generates a stationary magnetic field through an examination region (16), a gradient magnetic field system (18, 20, 22, 24) which applies magnetic field gradients across the examination region, and an RF system (26, 28, 32, 34, 36, 38) that applies RF excitation pulses to excite resonance in a subject in the examination region and receive magnetic resonance signals from the subject. A PET detector module (70) which is permanently or removably fixed in the examination region (16) to detect radiation from radiopharmaceuticals injected into the subject causes distortions in the magnetic field gradients. A plurality of probes (90) which are mounted in a fixed relationship to the PET detector module (70) measure magnetic field strength. A gradient magnetic field distortion correction system (110) determines distortions caused in the gradient magnetic fields and corrects the magnetic resonance signals accordingly.

Abstract: A TEM resonator system includes at least two TEM resonators, especially in the form of TEM volume coils, and especially for use in an MR imaging system or apparatus for transmitting RF excitation signals and/or for receiving MR signals into/from an examination object or a part thereof, respectively. The TEM resonators are arranged and displaced along a common longitudinal axis, and an intermediate RF shield is positioned in longitudinal direction between the two TEM resonators for at least substantially preventing electromagnetic radiation from emanating from between the first TEM resonator and the second TEM resonator into the surroundings.

Abstract: In a combined system, a magnetic resonance (MR) scanner includes a magnet configured to generate a static magnetic field at least in a MR examination region from which MR data are acquired. Radiation detectors are configured to detect gamma rays generated by positron-electron annihilation events in a positron emission tomography (PET) examination region. The radiation detectors include electron multiplier elements having a direction of electron acceleration arranged substantially parallel or anti-parallel with the static magnetic field. In some embodiments, the magnet is an open magnet having first and second spaced apart magnet pole pieces disposed on opposite sides of a magnetic resonance examination region, and the radiation detectors include first and second arrays of radiation detectors disposed with the first and second spaced apart magnet pole pieces.

Abstract: A combined-modality imaging assembly includes a Magnetic Resonance (MR) imaging system and a nuclear imaging system. The nuclear imaging system has a plurality of (M) modules; and the combined imaging assembly includes a timing control unit having a reference clock unit; and at least one of a phase shifting unit and a frequency shifting unit. At least one of the phase shifting unit and the frequency shifting unit is configured to receive a reference clock signal from the reference clock unit and to generate a plurality of (M) shifted clock signals for clocking the (M) modules such that at least one of the (M) shifted clock signals is shifted respective the reference clock signal in at least one of frequency or phase. In so doing, reduced interference between the modules of the nuclear imaging system and the MR imaging system is obtained.

Abstract: The invention concerns an evaluation apparatus (50) for evaluating gamma radiation events detected by a gamma camera (10) and identifying valid gamma radiation events, said (gamma camera (10) including a scintillator (12) for emitting scintillation photons (42) at photo conversion positions (44) in the scintillator (12) in response to incident gamma rays (22) and resulting gamma radiation events and a position-sensitive photodetector(14) for detecting emitted scintillation photons (42) and obtaining therefrom a spatial signal distribution (24). The invention further concerns a calibration apparatus (56) for in-situ calibrating a position-sensitive photodetector (14) of a gamma camera (10) for the detection of gamma radiation events.

Abstract: The invention relates to the integration of an energy function into a light management system, particularly for saving energy and monitoring energy consumption. According to an embodiment of the invention, a light management system (10) with an integrated energy function is provided, wherein the system is adapted to receiving energy information about light fixtures (12-16) of a lighting system (18), and to processing the received energy information with regard to energy consumption of the lighting system (18). The energy function may be for example used to automatically configure a lighting system to low energy consumption, to allow further configurations of the lighting system with regard to lowering energy consumption, or to provide a user with a sensible set of lights that can be turned off and will amount to significant energy savings when turned off.

Abstract: A method for scintillation event localization in a radiation particle detector includes providing a plurality of scintillator element locations (2?) configured to emit a burst of photons responsive to a radiation particle being absorbed at the scintillator element location (2?). A burst of photons emitted by the scintillator element location (2?) is detected with a photosensor (5). The photosensor (5) includes an array of single photon avalanche diodes configured to break down responsive to impingement of a photon. Breakdown data (30) is acquired indicative of which of the single photon avalanche diodes are in breakdown. Predetermined photosensor sensitivity data (20, 40) assigns single photon avalanche diodes to groups. Each group is assigned to exactly one scintillator element location (2?). Finally the number of single photon avalanche diodes in breakdown is determined for each group individually to identify the scintillator element location (2?) that emitted the burst of photons.

Abstract: The invention relates to a system for generating an estimate of a photon attenuation map for an object on the basis of single-scattered coincidences measured in a PET scanner. The system comprises a simulation module configured to calculate single-scattered coincidences by a numerical model calculation based on a preliminary attenuation map, where the estimate of the photon attenuation map is generated by adapting at least some attenuation values. The model calculation is made on the basis of a grid covering the object, the grid comprising grid elements (61) to which attenuation values are assigned, and the simulation module is further configured to determine at least one set of adjacent grid elements (61) in order to form a merged image element (63) including the set of adjacent grid elements (61) and to assign a single attenuation value to the merged image element in the model calculation.

Abstract: A method for determining the position of a scintillation event in a radiation particle detector with multiple scintillator element locations which are configured to emit a burst of photons responsive to a radiation particle being absorbed at the scintillator element location and with a plurality of photosensors (5.1, 5.2, 5.3, 5.4) optically coupled to said scintillator element locations, comprising the steps of determining, for each of the photosensors (5.1, 5.2, 5.3, 5.4), a triggering probability indicative of the probability of said photosensor (5.1, 5.2, 5.3, 5.4) measuring a number of photons that exceeds a predetermined triggering threshold; measuring a photon distribution with the photosensors (5.1, 5.2, 5.3, 5.4) indicative of the number of photons incident on the individual photosensors (5.1, 5.2, 5.3, 5.

Abstract: A method for determining the position of a scintillation event in a radiation particle detector with multiple scintillator element locations which are configured to emit a burst of photons responsive to a radiation particle being absorbed at the scintillator element location and with a plurality of photosensors (5.1, 5.2, 5.3, 5.4) optically coupled to said scintillator element locations, comprising the steps of determining, for each of the photosensors (5.1, 5.2, 5.3, 5.4), a triggering probability indicative of the probability of said photosensor (5.1, 5.2, 5.3, 5.4) measuring a number of photons that exceeds a predetermined triggering threshold; measuring a photon distribution with the photosensors (5.1, 5.2, 5.3, 5.4) indicative of the number of photons incident on the individual photosensors (5.1, 5.2, 5.3, 5.

Abstract: A method for scintillation event localization in a radiation particle detector comprises the steps of providing a plurality of scintillator element locations (2?) configured to emit a burst of photons responsive to a radiation particle being absorbed at the scintillator element location (2?) and detecting a burst of photons emitted by a scintillator element location (2?) with a photosensor (5), wherein the photosensor (5) comprises an array of single photon avalanche diodes configured to break down responsive to impingement of a photon. Breakdown data (30) is acquired indicative of which of the single photon avalanche diodes are in breakdown and predetermined photosensor sensitivity data (20, 40) is provided, which assign single photon avalanche diodes to groups, wherein each group is assigned to exactly one scintillator element location (2?).

Abstract: A ready to use catheter assembly comprises a catheter package with an opening, a catheter with a shaft arranged in the catheter package so a distal end of the catheter lies in the region of the opening, and a protective sleeve which partly covers the catheter shaft, a first end of the protective sleeve fixed to the distal end of the catheter. A method for producing a ready to use catheter assembly and a ready to use catheter assembly which further reduces the risk of an accidental contamination of a catheter when pulling it out of the catheter package prior to the insertion into the urethra of a user are provided. The opening has a defined maximum opening length, a second end of the protective sleeve is releasably connected which the catheter package near the maximum opening length of the opening and the protective sleeve is in a retracted state.

Abstract: An imaging system (36) includes a Positron Emission Tomography (PET) scanner (38) and one or more processors (52). The Positron Emission Tomography (PET) scanner (38) which generates event data including true coincident events and scatter events, the event data includes each end point of a line of response (LOR) and an energy of each end point. The one or more processors (52) are programmed to generate (72) a plurality of activity map and attenuation map pairs based on the true coincident events, and select (76) an activity map and an attenuation map from the plurality of activity and attenuation map pairs based on the scattered events.

Abstract: The invention relates to a computer-controlled lighting system which comprises an interface for defining a work surface within the lighting system and a desired illumination of the work surface, at least one luminaire for illuminating the work surface and a processing unit for automatically computing configuration parameters which allow configuring the at least one luminaire such that the desired illumination of the work surface is achievable.