Abstract: Some contrast injection systems use relatively-large inner diameter tubing to inject contrast fluid into a patient. The contrast injection system of the embodiments presented herein takes advantage of the elastic properties of tubing to “pre-stress” smaller inner diameter tubing into larger inner diameter tubing prior to injecting contrast into the patient. As such, the contrast injection system of these embodiments can reduce the risk of system-pressure-limit-induced injection interruption, improve maximum flow rate, and reduce the use of plastics.