Patents by Inventor Vrad Levering
Vrad Levering has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240066567Abstract: A defouling device for mechanically disrupting fouling material for removal from a pipe or other a tubular member. The defouling device has inflatable portions capable of expanding to mechanically disrupt fouling material within a pipe. The defouling device may be attached to an inner luminal surface of the pipe or formed with the pipe. The defouling device expands circumferentially and radially to mechanically disrupt fouling material. The defouling device may also controllably expand longitudinally to mechanically disrupt fouling material and peristaltically pump fouling material through and out of the pipe.Type: ApplicationFiled: October 18, 2023Publication date: February 29, 2024Inventor: Vrad Levering
-
Patent number: 11906719Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a formulation or implant device to a target location under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: GrantFiled: January 22, 2021Date of Patent: February 20, 2024Assignee: Spiral Therapeutics Inc.Inventors: Eugene de Juan, Hugo Peris, Signe Erickson, Vrad Levering
-
Publication number: 20240019674Abstract: Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.Type: ApplicationFiled: September 18, 2023Publication date: January 18, 2024Inventors: Eugene de Juan, Signe Erickson, Vrad Levering
-
Patent number: 11845114Abstract: A defouling device for mechanically disrupting fouling material for removal from a pipe or other a tubular member. The defouling device has inflatable portions capable of expanding to mechanically disrupt fouling material within a pipe. The defouling device may be attached to an inner luminal surface of the pipe or formed with the pipe. The defouling device expands circumferentially and radially to mechanically disrupt fouling material. The defouling device may also controllably expand longitudinally to mechanically disrupt fouling material and peristaltically pump fouling material through and out of the pipe.Type: GrantFiled: August 26, 2020Date of Patent: December 19, 2023Inventor: Vrad Levering
-
Patent number: 11796781Abstract: Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.Type: GrantFiled: January 22, 2021Date of Patent: October 24, 2023Assignee: Spiral Therapeutics Inc.Inventors: Eugene de Juan, Signe Erickson, Vrad Levering
-
Publication number: 20230258915Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: ApplicationFiled: April 24, 2023Publication date: August 17, 2023Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Hugo Peris, Andrew Ayoob, Vrad Levering
-
Patent number: 11662561Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: GrantFiled: January 22, 2021Date of Patent: May 30, 2023Assignee: Spiral Therapeutics Inc.Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Hugo Peris, Andrew Ayoob, Vrad Levering
-
Patent number: 11467386Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: GrantFiled: March 30, 2022Date of Patent: October 11, 2022Assignee: Spiral Therapeutics Inc.Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Hugo Peris, Andrew Ayoob, Vrad Levering
-
Publication number: 20220288655Abstract: A defouling device for mechanically disrupting fouling material for removal from a pipe or other a tubular member. The defouling device has inflatable portions capable of expanding to mechanically disrupt fouling material within a pipe. The defouling device may be attached to an inner luminal surface of the pipe or formed with the pipe. The defouling device expands circumferentially and radially to mechanically disrupt fouling material. The defouling device may also controllably expand longitudinally to mechanically disrupt fouling material and peristaltically pump fouling material through and out of the pipe.Type: ApplicationFiled: August 26, 2020Publication date: September 15, 2022Inventor: Vrad Levering
-
Publication number: 20220221700Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: ApplicationFiled: March 30, 2022Publication date: July 14, 2022Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Hugo Peris, Andrew Ayoob, Vrad Levering
-
Publication number: 20210338419Abstract: The present technology relates to modular valve replacement systems for treating valve-related cardiac disorders. In select embodiments, the modular valve replacement system includes a fixation device and a permanent valve assembly. The fixation device and the permanent valve assembly are delivered separately, enabling use of smaller delivery systems and facilitating less-invasive implant techniques. The fixation device is implanted first and provides a mounting fixture for the subsequently delivered permanent valve assembly. In some embodiments, the permanent valve assembly is at least partially mechanically isolated from the fixation device after the permanent valve assembly is attached to the fixation device. In some embodiments, the fixation device includes a temporary valve assembly that prevents regurgitation until the permanent valve assembly is implanted.Type: ApplicationFiled: October 7, 2019Publication date: November 4, 2021Inventors: Hanson S. Gifford, III, James I. Fann, Matthew McClean, Gaurav Krishnamurthy, Vrad Levering, Neil Zimmerman
-
Publication number: 20210228412Abstract: Devices, systems, and methods can be employed to facilitate performing procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. For example, this document describes devices, systems and methods that include instruments and techniques to minimize the invasiveness and/or to enhance the efficacy of procedures that are performed in the outer, middle, and/or inner ear spaces such as mastoidectomy, tympanoplasty, cholesteatoma treatments, otosclerosis treatments, and Eustachian tube treatments.Type: ApplicationFiled: January 22, 2021Publication date: July 29, 2021Inventors: Eugene de Juan, Hugo Peris, Signe Erickson, Vrad Levering, Nikhil Talreja
-
Publication number: 20210231935Abstract: Devices, systems, and methods can be employed to facilitate indirect viewing into cavities such as, but not limited to, the middle ear space. Some embodiments have uses such as, but not limited to, facilitating visualization and procedures in the outer, middle, and/or inner ear in order to diagnose and/or treat disorders including, but not limited to, hearing loss and other ear disorders. In particular implementations, a surgical microscope is used in conjunction with an inverter lens and a distal lens. In some cases, the distal lens transverses a membrane or septum such as, but not limited to, the tympanic membrane. The distal lens can be an assembly combining two or more lenses, in some embodiments. For example, in some cases wide angle lenses, zoom lenses, lenses of other various shapes and/or prisms can be used in the distal lens.Type: ApplicationFiled: January 22, 2021Publication date: July 29, 2021Inventors: Eugene de Juan, Signe Erickson, Vrad Levering
-
Publication number: 20210228411Abstract: Systems and methods can be employed for facilitating access and procedures in the outer, middle, and inner ear in order to diagnose or treat ear disorders including, but not limited to hearing loss and excessive ear wax. In some examples, the systems and methods include instruments and techniques that facilitate trans-tympanic membrane or trans-fibrous ring access to the middle ear. The systems and methods can also be used to improve accessibility for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: ApplicationFiled: January 22, 2021Publication date: July 29, 2021Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Vrad Levering
-
Publication number: 20210228237Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a therapeutic agent, for example, to the round window niche adjacent to the cochlea under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: ApplicationFiled: January 22, 2021Publication date: July 29, 2021Inventors: Eugene de Juan, Signe Erickson, Charles Limb, Hugo Peris, Andrew Ayoob, Vrad Levering
-
Publication number: 20210228235Abstract: Systems and methods can be employed for trans-tympanic membrane access to the middle ear for delivery of a formulation or implant device to a target location under direct visualization. The systems and methods can also be used to improve accessibility and visualization for various otological surgical procedures, such as, but not limited to, cholesteatoma removal, tympanic membrane repair and ossicular chain repair.Type: ApplicationFiled: January 22, 2021Publication date: July 29, 2021Inventors: Eugene de Juan, Hugo Peris, Signe Erickson, Vrad Levering
-
Publication number: 20070198077Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.Type: ApplicationFiled: January 18, 2007Publication date: August 23, 2007Inventors: Edward Cully, Jeffrey Duncan, Keith Flury, Paul Goodman, Wayne House, Vrad Levering, Philip Off, Daniel O'Shea, Michael Vonesh, Jason Wiersdorf