Abstract: Expandable devices are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a stent configured to be expanded within a body conduit of a human patient. The stent may comprise a tubular sidewall having first portions and second portions. Radial expansion of the stent may cause the first portions to bow outwardly and out of radial alignment with the second portions.

Abstract: Devices, systems, and methods for treating a blood flow passage are disclosed herein. For example, expandable devices of the present technology may comprise a stent having a collapsed configuration for delivery through a delivery device to a treatment site in a body conduit and an expanded configuration. The stent may comprise a plurality of struts and longitudinally extending first and second spines configured to move in opposing axial directions as the stent expands. Each of the struts may extend between and connect one of the first spines and one of the second spines. Moving the first spines axially relative to the second spines may cause the struts to push circumferentially adjacent spines to move away from one another, thereby increasing a diameter of the stent.

Abstract: Expandable devices are disclosed herein. Several of the embodiments are directed towards an expandable device configured to be expanded within a conduit. The expandable device may comprise a tubular sidewall having first portions and second portions. Radial expansion of the expandable device may cause the first portions to bow outwardly and out of radial alignment with the second portions.

Abstract: Systems (1100) for treating a blood flow passage are discloses herein. In one example, a treatment device includes an expandable element (1104) configured to be positioned within the passage and a reinforcing element (1102). The expandable element may have an expanded configuration in which the expandable element defines a lumen (1108) therethrough. The reinforcing element may be positioned within the lumen of the expandable element. The reinforcing element may be coupled to the expandable element such that expansion of the expandable element causes the reinforcing element to radially expand, thereby creating a perfusion lumen through the device.

Abstract: Devices, systems, and methods for treating a blood flow passage are discloses herein. In one example, a treatment device includes an expandable element configured to be positioned within the passage and a reinforcing element. The expandable element may have an expanded configuration in which the expandable element defines a lumen therethrough. The reinforcing element may be positioned within the lumen of the expandable element. The reinforcing element may be coupled to the expandable element such that expansion of the expandable element causes the reinforcing element to radially expand, thereby creating a perfusion lumen through the device.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.

Abstract: Disclosed herein are devices and methods for active biofouling control. According to an aspect, a device comprising a surface for contacting a biological material. The device also comprises a mechanism comprising a structure configured to change the surface between a first shape and a second shape. The change from the first shape to the second shape deforms the surface beyond a critical strain for debonding of a fouling agent from the surface when the fouling agent has bonded to the surface in the first shape.

Abstract: Catheters for debonding fouling agents from an interior surface thereof and related methods are disclosed. According to an aspect, a catheter includes a lumen defining a flexible, interior surface that extends substantially along a length of the lumen for contacting a biological material. The catheter also includes cavities extending along the length and positioned within the lumen adjacent to the surface. The cavities each define a cavity opening. The catheter also includes an inflation hub defining hub openings connected to respective cavity openings. The inflation hub defines a pump port configured to interface with a pump. The inflation hub defines one or more fluid pathways that extend between the hub openings and the pump port for permitting flow of gas between the pump and the cavities.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.

Abstract: Disclosed herein are devices and methods for active biofouling control. According to an aspect, a device comprising a surface for contacting a biological material. The device also comprises a mechanism comprising a structure configured to change the surface between a first shape and a second shape. The change from the first shape to the second shape deforms the surface beyond a critical strain for debonding of a fouling agent from the surface when the fouling agent has bonded to the surface in the first shape.

Abstract: A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath.