Patents by Inventor Vu Truong-Le

Vu Truong-Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preservation of bioactive materials by freeze dried foam
    Patent number: 7135180
    Abstract: This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: November 14, 2006
    Assignee: MedImmune Vaccines, Inc.
    Inventor: Vu Truong-Le
  • High pressure spray-dry of bioactive materials
    Publication number: 20060002862
    Abstract: This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents, organic solvents, and/or surfactants. Formulations are provided for spraying therapeutic bioactive materials into powder particles containing amino acids and sugars. Compositions of the invention provide, e.g., high initial purity, high stability in storage, and reconstitution at high concentrations.
    Type: Application
    Filed: June 13, 2005
    Publication date: January 5, 2006
    Applicant: MedImmune Vaccines, Inc.
    Inventors: Vu Truong-Le, Tom Scherer
  • Methods of producing influenza vaccine compositions
    Publication number: 20040265987
    Abstract: Methods and compositions for the optimization of production of influenza viruses suitable as influenza vaccines are provided.
    Type: Application
    Filed: February 25, 2004
    Publication date: December 30, 2004
    Applicant: Medlmmune Vaccines, Inc.
    Inventors: George Robert Trager, George Kemble, Richard M. Schwartz, Harshvardhan Mehta, Vu Truong-Le, Zhongying Chen, Alfred A. Pan, Eric Tsao, Chiaoyin Kathy Wang, Luisa Yee, Palani Balu
  • High pressure spray-dry of bioactive materials
    Publication number: 20040185091
    Abstract: This invention provides compositions and methods providing, e.g., stable powder particles containing bioactive materials. The methods include, e.g., high pressure spraying of the bioactive materials in solution or suspension, with viscosity enhancing agents and/or surfactants. Compositions of the invention provide, e.g., high initial purity, high stability in storage, and reconstitution at high concentrations.
    Type: Application
    Filed: December 16, 2003
    Publication date: September 23, 2004
    Applicant: Medlmmune Vaccines, Inc.
    Inventors: Vu Truong-Le, Tom Scherer
  • Spray freeze dry of compositions for intranasal administration
    Publication number: 20040042972
    Abstract: This invention provides methods and compositions to preserve bioactive materials, such as peptides, nucleic acids, viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for intranasal administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles for intranasal administration.
    Type: Application
    Filed: April 10, 2003
    Publication date: March 4, 2004
    Applicants: MedImmune Vaccines, inc., The Regents of the University of Colorado, a body corporate,
    Inventors: Vu Truong-Le, Binh V. Pham, John F. Carpenter, Robert Seid, Theodore W. Randolph
  • Spray freeze dry of compositions for pulmonary administration
    Publication number: 20040042971
    Abstract: This invention provides methods and compositions to preserve bioactive materials, such as viruses, bacteria, cells, or liposomes, in freeze dried particles suitable for pulmonary administration. Methods provide spray freeze drying of formulations to form stable freeze dried particles.
    Type: Application
    Filed: April 10, 2003
    Publication date: March 4, 2004
    Applicants: MedImmune Vaccines, Inc., The Regents of the University of Colorado, a Body Corporate, Boulder, Co
    Inventors: Vu Truong-Le, Binh V. Pham, John F. Carpenter, Robert Seid, Theodore W. Randolph
  • Preservation of bioactive materials by freeze dried foam
    Publication number: 20030219475
    Abstract: This invention provides methods and compositions to preserve bioactive materials in a dried foam matrix. Methods provide non-boiling foam generation and penetration of preservative agents at temperatures near the phase transition temperature of the membranes.
    Type: Application
    Filed: April 10, 2003
    Publication date: November 27, 2003
    Applicant: Medlmmune Vaccines, Inc.
    Inventor: Vu Truong-Le
  • Preservation of bioactive materials by spray drying
    Publication number: 20030215515
    Abstract: This invention provides methods and compositions to preserve bioactive materials in a matrix of powder particles. Methods provide high-pressure gas spraying and/or near supercritical spraying of formulations followed by drying in a stream of conditioned gas to form stable powder particles containing bioactive materials.
    Type: Application
    Filed: April 10, 2003
    Publication date: November 20, 2003
    Applicant: MedImmune Vaccines, Inc.
    Inventors: Vu Truong-Le, Binh Pham