Patents by Inventor W. Bradford Middlekauff

W. Bradford Middlekauff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250066467
    Abstract: The present disclosure provides methods of treating myasthenia gravis comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of myasthenia gravis.
    Type: Application
    Filed: November 16, 2023
    Publication date: February 27, 2025
    Inventors: Sandeep KULKARNI, Yung CHYUNG, Susan Dana JONES, Ryan IARROBINO, W. Bradford MIDDLEKAUFF
  • Publication number: 20250011416
    Abstract: The present disclosure provides methods of treating cardiovascular disease comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of cardiovascular disease.
    Type: Application
    Filed: September 18, 2024
    Publication date: January 9, 2025
    Inventors: Sandeep Kulkarni, Yung Chyung, Susan Dana Jones, Ryan Iarrobino, W. Bradford Middlekauff
  • Publication number: 20250011417
    Abstract: The present disclosure provides methods of treating thyroid eye disease comprising subcutaneously administering to a patient in need thereof a therapeutically effective dose of an anti-interleukin-6 (anti-IL-6) antibody or antibody fragment. Further provided herein are pharmacologically active agents, compositions, methods and/or dosing schedules for the treatment of thyroid eye disease.
    Type: Application
    Filed: September 18, 2024
    Publication date: January 9, 2025
    Inventors: Sandeep Kulkarni, Yung Chyung, Susan Dana Jones, Ryan Iarrobino, W. Bradford Middlekauff