Patents by Inventor W. D. Tigertt

W. D. Tigertt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay of gentamicin in blood
    Patent number: 3948729
    Abstract: The ability of gentamicin to inhibit urease synthesis by a gentamicin susceptible strain of an adaptive urease producing microorganism is employed to provide an assay for the concentration of gentamicin present in the blood of a patient being treated with gentamicin. The gentamicin concentration in the liquid portion of blood is determined by comparing the amount of C.sup.14 O.sub.2 produced by a gentamicin susceptible strain of an adaptive urease producing microorganism from a culture medium containing an aliquot of blood test sample and a measured amount of C.sup.14 urea with the C.sup.14 O.sub.2 produced by that microorganism from controls using known concentrations of gentamicin in blood samples.
    Type: Grant
    Filed: March 18, 1974
    Date of Patent: April 6, 1976
    Assignee: Johnston Laboratories, Inc.
    Inventors: Gardner Middlebrook, W. D. Tigertt