Abstract: The present invention relates to methods and compositions for the treatment and/or prevention of actinic keratoses comprising a calcium channel blocking compound.

Abstract: A topical medicament and associated methodology for use thereof, through the use of which tissue disorders involving collagen degeneration associated with repetitive microtears of the plantar fascia may be effectively, cost effectively, and painlessly treated. One or more calcium channel blocker agents serve as the primary active ingredient of the present compositions, with carrier agents facilitating non-invasive transdermal delivery of the calcium channel blocker(s) to sub-dermal disease sites.

Abstract: A medicament and associated treatment involving the use of such medicament for the treatment of vulvodynia. The medicament is in the dosage form of a vaginal suppository, and the primary active ingredient is a calcium antagonist Diltiazem Hydrochloride in the preferred embodiment.

Abstract: The invention is of a topical medicament and associated methodology for use thereof, through the use of which fibrosis of the elastic tissues and muscle of the human penis is reduced, thereby improving erectile function and/or reversing erectile dysfunction. One or more calcium channel blocker agents serve as the primary active ingredient of the present compositions, with carrier agents facilitating non-invasive transdermal delivery of the calcium channel blocker(s) to fibrotic tissues of the penis.