Abstract: A dispensing system (40) includes a body (54) having an outer wall (64) defining a volume for storing a substance, the outer wall (64) having a top end (66) and a sealed bottom end (70). The top end (66) is covered by a flexible lid (56) that is attached to the body (54). The lid (56) has a press portion (88) for being engaged to move the lid (56) from a first position into a second, deflected position. A post (58) is connected to the lid (56) and is configured in the second position of the lid (56) to breach the sealed bottom end (70) forming a dispensing orifice (80) to accommodate movement of a substance out of the body (54). In one form, the outer wall (64) includes at least one bottle stop projection (218) defining one or more vent channels (219).

Abstract: A dispensing system (40) includes a body (54) having an outer wall (64) defining a volume for storing a substance, the outer wall (64) having a top end (66) and a sealed bottom end (70). The top end (66) is covered by a flexible lid (56) that is attached to the body (54). The lid (56) has a press portion (88) for being engaged to move the lid (56) from a first position into a second, deflected position. A post (58) is connected to the lid (56) and is configured in the second position of the lid (56) to breach the sealed bottom end (70) forming a dispensing orifice (80) to accommodate movement of a substance out of the body (54). In one form, the outer wall (64) includes at least one bottle stop projection (218) defining one or more vent channels (219).

Abstract: A closure (40, 40A, 40B) for use with a container includes a body (54, 54A, 54B) defining a passage (72, 72A, 72B) and a first latch portion (92, 92B). The closure (40, 40A, 40B) has a lid (56, 56A, 56B) defining a deflectable press portion (96, 96A, 96B) that has a connection (100, 100A, 100B) to the closure body (54, 54A, 54B). The lid (56, 56A, 56B) has a cover portion (100, 100A, 100B) including a second latch portion (120, 120A, 120B) for engaging the first latch portion (92, 92B) to releasably hold the cover portion (100, 100A, 100B) in a latched closed position in which the cover portion (100, 100A, 100B) at least partially occludes the passage (72, 72A, 72B). The lid (56, 56A, 56B) has a biased hinge (104, 104A, 104B) connecting the cover portion (100, 100A, 100B) with the press portion (96, 96A, 96B) to accommodate movement of the cover portion (100, 100A, 100B) between the latched closed position and an unlatched open position.

Abstract: A user interface device and method for biometric information processing in a user interface device for biometric collection, quality checking, and matching are disclosed. Embodiments provide a user interface device for capturing biometric information (such as fingerprints) of a subject, determining the quality of the captured biometric information, and comparing the captured biometric information to stored biometric information for possible matches. Comparisons using high quality captured biometric information result in quicker and more accurate verification of identities.

Abstract: In some embodiments, a catheterization device includes a tip and includes a body member having a proximal end and a distal end. The body member can define a lumen that extends from the proximal end to the distal end. The catheterization device further includes an expandable portion extending between the tip and the proximal end of the body member. The expandable portion can include a plurality of arms bent to form a resting shape. The expandable member may be configured to expand to allow the body member to extend in response to tension applied to the body member and to retract to the resting shape when tension is withdrawn.

Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an Fc?R or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.

Abstract: A user interface device and method for biometric information processing in a user interface device for biometric collection, quality checking, and matching are disclosed. Embodiments provide a user interface device for capturing biometric information (such as fingerprints) of a subject, determining the quality of the captured biometric information, and comparing the captured biometric information to stored biometric information for possible matches. Comparisons using high quality captured biometric information result in quicker and more accurate verification of identities.

Abstract: Hybridization assay detection probes targeted to HPV Type 16 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 are described. The oligonucleotides can aid in detecting HPV Type 16 by acting singly or as part of a detection probe mixture. Compositions, reaction mixtures and methods of use are provided.

Abstract: A diaphragm pump (12) is provided for a fluent product dispensing package (10), and includes a rigid pump base (22), a pumping dome (20), and an outlet valve (122). The dome (20) can include a mount ring (30) and a flexible dome member (32) that are permanently bonded to each other, with the ring (30) and the base (22) configured to provide a releasable connection for retaining the dome (20) to the base (22). The valve (122) can be part of an outlet valve cartridge (28) that includes the valve (122), a valve base (120) configured to releasably mount the outlet valve cartridge (26) to the base (22), and a retaining ring (124) for retaining the valve (122) to the base (120).

Abstract: Hybridization assay detection probes targeted to HPV Type 16 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 are described. The oligonucleotides can aid in detecting HPV Type 16 by acting singly or as part of a detection probe mixture. Compositions, reaction mixtures and methods of use are provided.

Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.

Abstract: A method and system are provided for delivering calling party notifications. An artificial intelligence software application located on an Intelligence Rules Server is operable to infer why a first call to a mobile station is not connected and predict when a second call to a mobile station is likely to be connected. The application communicates the inference and the prediction to a voice messaging system. The voice messaging system delivers a message to a calling party based on the inference and/or the prediction.

Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an Fc?R or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.

Abstract: A system and method for providing secure network services. A secure computer including a processor, a memory, and a secure operating system is discussed. The secure operating system includes an operational kernel and an administrative kernel. The operational kernel includes a Type Enforcement security mechanism for restricting execution of files stored in the memory by the processor. The execution restrictions placed on files in the memory of the secure computer can only be modified from within the administrative kernel.

Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.

Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.

Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.

Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.

Abstract: A device can connect to a packet data network through a first data channel, such as a connection with a wireless telecommunications network. The device can additionally connect to the packet data network through a second data channel. The device can simultaneously transmit data over the first and second data channels. Data channels can be added or removed in order to change the bandwidth available to the device.

Abstract: The present invention provides novel human anti-cancer antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of cancer.