Patents by Inventor W. Michael Scheld

W. Michael Scheld has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATING ANTHRAX LETHALITY
    Publication number: 20100247525
    Abstract: The present invention provides compositions and methods for preventing and inhibiting anthrax lethality. The present invention relates to protect a subject from anthrax lethality by presensitizing a subject prior to anthrax infection. The present invention further provides compositions and methods for enhancing the innate system to inhibit anthrax-associated lethality. The invention further provides compositions and methods for preventing and inhibiting lethality due to infection regulated via a TNF-? pathway.
    Type: Application
    Filed: May 8, 2007
    Publication date: September 30, 2010
    Applicant: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
    Inventors: Edward N. Martin, JR., W. Michael Scheld
  • ADJUNCTIVE TREATMENT OF BIOLOGICAL DISEASES
    Publication number: 20090170803
    Abstract: The present invention provides a therapeutic method for treating biological diseases that includes the administration of an effective amount of a suitable antibiotic agent, antifungal agent or antiviral agent in conjunction with an A2A adenosine receptor agonist. If no anti-pathogenic agent is known the A2A agonist can be used alone to reduce inflammation, as may occur during infection with antibiotic resistant bacteria, or certain viruses such as those that cause SARS or Ebola. Optionally, the method includes administration of a type IV PDE inhibitor.
    Type: Application
    Filed: April 10, 2003
    Publication date: July 2, 2009
    Inventors: Joel M. Linden, Gail W. Sullivan, W. Michael Scheld, Tom Gordon Obrig, Timothy L. MacDonald, Jayson M. Rieger
  • Pharmaceutical compositions having Aadenosine receptor agonist activity
    Patent number: 7226913
    Abstract: The present invention provides compositions for oral administration of compounds having A2A adenosine receptor agonist activity. These compositions are useful for treatment of inflammatory conditions.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: June 5, 2007
    Assignee: University of Virginia Patent Foundation
    Inventors: Joel M. Linden, Gail W. Sullivan, Ian J. Sarembock, Timothy MacDonald, Mark Okusa, Irving L. Kron, W. Michael Scheld
  • Methods and compositions for treating inflammatory response
    Publication number: 20030162742
    Abstract: Compositions for oral administration of compounds having A2A adenosine receptor antagonist activity are provided. These compositions are useful for treatment of inflammatory conditions.
    Type: Application
    Filed: March 3, 2003
    Publication date: August 28, 2003
    Applicant: University of Virginia Patent Foundation, University of Virginia.
    Inventors: Joel M. Linden, Gail W. Sullivan, Ian J. Sarembock, Timothy MacDonald, Mark Okusa, Irving L. Kron, W. Michael Scheld
  • Methods and compositions for treating inflammatory response
    Patent number: 6531457
    Abstract: Compounds and methods are provided to treat inflammatory conditions with certain A2A adenosine receptor antagonists.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: March 11, 2003
    Assignees: University of Virginia, University of Virginia Patent Foundation
    Inventors: Joel M. Linden, Gail W. Sullivan, Ian J. Sarembock, Timothy MacDonald, Mark Okusa, Irving L. Kron, W. Michael Scheld
  • Method compositions for treating the inflammatory response
    Patent number: 6514949
    Abstract: Agonists of A2A adenosine receptors optionally, in combination with a Type IV phosphodiesterase (PDE) inhibitor are effective for the treatment of the inflammatory response of mammalian tissue.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: February 4, 2003
    Assignees: University of Virginia Patent Foundation, University of Virginia
    Inventors: Joel M. Linden, Gail W. Sullivan, W. Michael Scheld
  • Methods and compositions for treating inflammatory response
    Publication number: 20010027185
    Abstract: Compounds and methods are provided to treat inflammatory conditions with certain A2A adenosine receptor antagonists.
    Type: Application
    Filed: April 5, 2001
    Publication date: October 4, 2001
    Applicant: University of Virginia Patent Foundation
    Inventors: Joel M. Linden, Gail W. Sullivan, Ian J. Sarembock, Timothy MacDonald, Mark Okusa, Irving L. Kron, W. Michael Scheld