Abstract: An enclosure for luggage for use on a vehicle cartop luggage rack of the type including either front and rear rails disposed in a spaced, parallel relationship, or else an essentially rectangularly shaped frame, mounted generally horizontally on the cartop. This enclosure utilizes rapidly operated securing devices on its front and back panels when intended for use on a two rail rack, or rapidly operated securing devices on all four of its peripheral panels when intended for use with a luggage rack principally constituted by front, back and side rails. In the latter type rack, the subject enclosure for luggage is insertable into the space defined by the four rails. Flexible, watertight material having front and back surfaces as well as side surfaces is used, and an access opening is provided in an upper part of the enclosure.