Abstract: Systems and methods for minimally invasive tele-surgery are described. For example, the disclosure describes methods for independently controlling motions of the robotic manipulator, cannula, and surgical instrument in various surgical contexts.

Abstract: Systems and methods for image detection during grasping and stapling include an end effector having a first jaw and a second jaw, an imaging sensor mounted to the end effector and configured to capture images of a material graspable by the end effector, and one or more processors coupled to the end effector and the imaging sensor. The one or more processors are configured to receive the images from the imaging sensor, determine one or more properties of the material based on the images, and display the one or more properties of the material on an interface. In some embodiments, the end effector is part of a medical tool and the material is anatomical tissue. In some embodiments, the end effector further includes one or more of a stapling mechanism configured to staple the material or a cutting mechanism configured to cut the material.

Abstract: A wheel alignment system includes a side-to-side reference including an active reference pod and a passive reference pod disposed on opposite sides of the vehicle. The active reference pod includes a reference image sensor fixedly attached to a reference target, for mounting on a first side of the vehicle such that the reference image sensor produces image data including a perspective representation of the passive reference pod disposed on a second/opposite side of the vehicle. In operation, alignment cameras on the opposite sides of the vehicle capture perspective representations of targets mounted to vehicle wheels and of targets of the active and passive reference pods. A computer processes the image data to compute an alignment measurement of the vehicle based on a spatial relationship between the active reference pod and the passive reference pod determined according to the image data produced by the reference image sensor.

Abstract: Vortex arc reactor apparatus and method provide a nozzle with converging, throat, and diverging portions. Input structure inputs a reactant and an oxidant into the converging portion. Ignition structure ignites the input reactant and oxidant. A vortex-creating structure creates a vortex of the ignited reactant and oxidant in the converging portion. The input structure, the vortex-creating structure, and the nozzle converging and throat portions are configured to provide a throat-portion-vortex of ignited reactant and oxidant that has an angular velocity which provides (i) negatively-charged particles in an exterior portion of the throat-portion-vortex, (ii) positively-charged particles in an interior portion of the throat-portion-vortex, and (iii) at least one arcing reaction between the positively-charged particles and the negatively-charged particles, to form syngas and at least one aromatic liquid in the nozzle diverging portion.

Abstract: An aerosol delivery device includes a receptacle configured to receive a substrate configured to carry an aerosol precursor composition, and a resonant transformer including a transmitter coupling device and a resonant receiver coupling device that is positioned in proximity to the substrate when received in the receptacle. The aerosol delivery device also includes a pulse width modulation (PWM) inverter configured to drive the resonant transformer. The PWM inverter includes a bridge circuit coupled to the transmitter coupling device, and a PWM controller embodied as an integrated circuit and configured to output a PWM signal to the bridge circuit configured to drive the transmitter coupling device to generate an oscillating magnetic field and induce an alternating voltage in the resonant receiver coupling device when exposed to the oscillating magnetic field.

Abstract: A teleoperated surgical system is provided that comprises a support arm; a surgical instrument, moveably mounted to the support arm, including a housing a proximal end portion and a distal end portion and having an end effector at the distal end portion thereof; an actuator to impart movement to the surgical instrument; an optical fiber, including a proximal end portion and a distal end portion, mounted to the surgical instrument to emit first light from its distal end at the distal end portion of the surgical instrument; and a light source disposed to impart the first light to the proximal end of the optical fiber at a first angle within an acceptance angle of the optical fiber.

Abstract: Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. In particular, described herein are compositions of decanoic acid:Arginine in which the decanoic acid and Arginine for a complex having a lamellar supramolecular structure.

Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and as assembling them into syringes, e.g., pre-filled syringes.

Abstract: Methods for using a surgical device integrating a suction mechanism with a coagulation mechanism for improving lesion creation capabilities. The device comprises an elongate member having an insulative covering attached about means for coagulating soft tissue. Openings through the covering expose regions of the coagulation-causing elements and are coupled to lumens in the elongate member which are routed to a vacuum source and a fluid source to passively transport fluid along the contacted soft tissue surface in order to push the maximum temperature deeper into tissue.

Abstract: A radiation finder tool assists in locating tissue of interest within a patient. The radiation finder tool includes a body and a plurality of radiation detectors. The body has a distal end, a proximal end. A lengthwise axis of the radiation finder tool extends between the proximal end and the distal end of the body. The plurality of radiation detectors is oriented serially along the lengthwise axis, e.g., stacked one after the other along the lengthwise axis. Each radiation detector of the plurality of radiation detectors has a different field of view for radiation detected by that radiation detector. Each field of view of the plurality of radiation detectors has the lengthwise axis at its center.

Abstract: Methods and devices described herein facilitate diaphragm entry for posterior access of body organs.

Abstract: An apparatus includes a reference fixture. The reference fixture includes a joint, and a joint tracker to track motion of the joint. The apparatus also includes a surgical instrument. A tether is connected between the joint and the surgical instrument. A shape sensor extends from the reference fixture through the joint, through the tether, and into the surgical instrument. The shape sensor is substantially free of twist. The joint tracker measures the motion of the joint. Information from the shape sensor in combination with information from the joint tracker provides absolute three-dimensional information relative to the reference fixture, i.e., provides absolute three-dimensional information in a fixed world reference frame.

Abstract: The present disclosure relates to certain macrocyclic derivatives, pharmaceutical compositions containing them, and methods of using them to treat disease, such as cancer.

Abstract: A surgical tool having an elongated shaft having a proximal end and distal end. A surgical end effector is located about the distal end. The surgical end effector has a plurality of effector mechanisms comprising a plurality of degree of freedoms. An effector body is located at the proximal end. The effector body includes a plurality of motor interfaces for driving the plurality of effector mechanisms. A transmission is coupled to the effector body.

Abstract: An instrument manipulator may comprise a frame comprising an outer shell and an inner frame, the inner frame being movably coupled to the outer shell. The instrument manipulator may also include a plurality of actuator outputs protruding in a distal direction from the frame and an instrument support feature coupled to the outer shell. The instrument manipulator may further comprise a latching mechanism, the latching mechanism being configured to move the inner frame, the outer shell, or both relative to one another, so as to operably engage the plurality of actuator outputs with a plurality of actuator inputs of an instrument supported by the instrument support feature.

Abstract: A cannula can include a body with proximal and distal portions and a lumen extending through the body, the distal portion configured for insertion into a patient anatomy. An energy interface can be positioned in the proximal portion, and a light emitting device can be coupled to the energy interface and configured to emit light from the body. A system can include the cannula, a support structure, and an energy source. The support structure can include another energy interface that transfers energy to/from the energy interface. The energy source can be coupled to the cannula via the energy interfaces, where the light emitting device emits light from the body in response to energy received from the energy source via the energy interfaces. One or more cannulae can be used to illuminate the patient anatomy.

Abstract: A vehicle wheel alignment system has a plurality of cameras, each camera for viewing a respective target disposed at a respective wheel of the vehicle and capturing image data of the target as the wheel and target are continuously rotated a number of degrees of rotation without a pause. The image data is used to calculate a minimum number of poses of the target of at least one pose for every five degrees of rotation as the wheel and target are continuously rotated the number of degrees of rotation without a pause. At least one of the cameras comprises a data processor for performing the steps of preprocessing the image data, and calculating an alignment parameter for the vehicle based on the preprocessed image data.

Abstract: A method of biasing a drywall corner flusher and a drywall corner flusher biased in accordance with the method. The method involves moulding a “V” shaped corner flusher body from a resilient material. The corner flusher body having a pair of blades each having a common edge and a remote edge, with the pair of blades being connected along the common edge. The corner flusher body is moulded with an integrally moulded undulating rib extending from the remote edge of one blade of the pair of blades to the remote edge of another blade of the pair of blades biasing the remote edge of each of the pair of blades outwardly.

Abstract: Compositions including a complex of fatty acids (e.g., including one or more C4 to C40 fatty acids, such as a C4 to C20 fatty acid) and one or more amino acids (and particularly one or more amino acids having electrically charged basic side chains, e.g., Arginine, Lysine, etc.) for use as an anti-pathogenic composition. These compositions may include the complex of fatty acid:amino acid having a lamellar supramolecular structure. In particular, described herein are therapeutic compositions of undecylenic acid:Arginine forming a complex of undecylenic acid and Arginine.

Abstract: An exemplary lighting system utilizes intelligent system elements, such as lighting devices, user interfaces for lighting control or the like and possibly sensors, and utilizes network communication amongst such intelligent system elements. Some processing functions performed within the system are implemented on a distributed processing basis, by two or more of the intelligent elements of the lighting system. Distributed processing, for example, may enable use of available processor and/or memory resources of a number of intelligent system elements to process a particular job. Another distributed processing approach might entail programming to configure two or more of the intelligent system elements to implement multiple instances of a server functionality with respect to client functionalities implemented on intelligent system elements.