Patents by Inventor W. Wardle Fullerton

W. Wardle Fullerton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic complex from N. gonorrhoeae
    Patent number: 4386066
    Abstract: A vesicular, immunogenic, non-pyrogenic complex is obtained from isolates of N. gonorrhoeae by cultivating N. gonorrhoeae on a suitable nutrient medium; harvesting and centrifuging the cells; extracting the cell pellet with TRITON X-100 at alkaline pH; suspending the solids remaining after extraction in aqueous medium and precipitating in the cold with ethanol.
    Type: Grant
    Filed: August 20, 1981
    Date of Patent: May 31, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Edward C. O'Rourke, W. Wardle Fullerton
  • Surfactant assay
    Patent number: 4292041
    Abstract: Thin layer chromatography is used to separate various surfactants. The support medium is silica gel on a glass or acrylamide plate. The developing solvent is chloroform/methanol/water. After drying, the surfactants are detected at extremely low levels with iodine vapor, rhodamine 6G in methanol or phosphomolybdic acid in ethanol/ether, or radiolabelled surfactant. A method is given for the separation of surfactants from proteins or glycoproteins or lipoproteins or polysaccharides, or lipopolysaccharides.
    Type: Grant
    Filed: November 2, 1979
    Date of Patent: September 29, 1981
    Assignee: Merck & Co., Inc.
    Inventor: W. Wardle Fullerton
  • Viral liposome particle
    Patent number: 4261975
    Abstract: The outer membrane of influenza virus is attached to a liposome by two different techniques. In addition, one of the techniques allows the entrapment of intact virus, usually one virus per liposome. The techniques can be performed with either influenza virus A or B.
    Type: Grant
    Filed: September 19, 1979
    Date of Patent: April 14, 1981
    Assignee: Merck & Co., Inc.
    Inventors: W. Wardle Fullerton, Bohdan Wolanski
  • Process for recording data in the leucocyte migration inhibition assay
    Patent number: 4254219
    Abstract: A method of detecting and quantitating the migration of leucocytes in agar gel by (1) fixing the cells; (2) staining them with Ponceau S or a similar dye; (3) destaining; and (4) dissolving the gel by gentle heating in the destaining solution. The stained cells remain adhered to the glass surface of the culture dish, and the cells can be read through a projection microscope or photographed for a permanent record.
    Type: Grant
    Filed: September 21, 1979
    Date of Patent: March 3, 1981
    Assignee: Merck & Co., Inc.
    Inventor: W. Wardle Fullerton
  • Apparatus for longitudinal slicing of cylindrical body
    Patent number: 4194424
    Abstract: This invention relates to an apparatus for slicing cylindrically shaped columns of gels. More particularly, it relates to an apparatus for firmly holding cylindrical columns of acrylamide gel while making a longitudinal slice through the entire length of the column.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: March 25, 1980
    Assignee: Merck & Co., Inc.
    Inventors: Edward C. O'Rourke, W. Wardle Fullerton