Abstract: An automated peritoneal dialysis apparatus includes at least one pump and a memory device configured to simultaneously store a first standard ultrafiltration (“UF”) therapy prescription with a longer duration and a lower dextrose concentration and a second standard UF therapy prescription with a shorter duration and a higher dextrose concentration. A logic implementer of the automated peritoneal dialysis apparatus is programmed to receive a patient weight value and determine a weight difference between the patient weight value and at least one prior patient weight value. When the weight difference is below a threshold, the logic implementer causes the first standard UF therapy prescription and the second standard UF therapy prescription to be displayed as possible options for selection and when the weight difference is above the threshold, the logic implementer prevents the second standard UF therapy prescription from being displayed as a possible option for selection.

Abstract: The invention relates to computer-implemented systems and methods for automatically discerning creation of handwritten verbiage (or typed) on a digital display; converting it to digital text objects that have been repaired (e.g., spelling, punctuation, etc.); and then inserting it as Scalable Vector Graphics onto the display.

Abstract: Techniques are disclosed relating to application verification. In various embodiments, a computing device includes a secure circuit configured to maintain a plurality of cryptographic keys of the computing device. In such an embodiment, the computing device receives, from an application, a request for an attestation usable to confirm an integrity of the application, instructs the secure circuit to use one of the plurality of cryptographic keys to supply the attestation for the application, and provides the attestation to a remote computing system in communication with the application. In some embodiments, the secure circuit is configured to verify received metadata pertaining to the identity of the application and use the cryptographic key to generate the attestation indicative of the identity of the application.

Abstract: An example peritoneal dialysis system is disclosed. The example peritoneal dialysis system includes at least one pump and a memory device configured to store therapy prescriptions including a low ultrafiltration (“UF”) therapy prescription, a first standard UF therapy prescription with a longer duration and a lower dextrose concentration, and a second standard UF therapy prescription with a shorter duration and a higher dextrose concentration. The memory device also stores a schedule indicative as to which of the therapy prescriptions are to be performed on specified dates. The system further includes a logic implementer configured to determine or identify a current date, use the schedule stored in the memory device to select the therapy prescription based on the current date, and control the at least one pump based on the selected therapy prescription to perform a peritoneal dialysis therapy.

Abstract: A surgeon training apparatus includes a cassette, which includes biological tissue repurposed into a form consistent with the anatomical configuration of abdominal hernias, affixed into an anatomically correct silicon framework which replicates the abdominal anatomy. The framework positions the cassette in an anatomically correct position within the abdominal cavity, enabling surgeons to train using a properly positioned representation of the target anatomy, thus requiring the surgeon to properly use surgical tools to correct the pathologic condition caused by the hernia. The cassette is formed by applying biologic tissue to a specially designed “plate,” which affixes the tissue block into the anatomic framework, and is adapted for connection to a grounding device so the surgeon can use cautery during the simulated hernia repair.

Abstract: According to embodiments, a method for navigating clusters of a data structure includes gathering data from the data structure by instrumenting instances of application software executing on the data structure. The method also includes identifying clusters of the data structure based on the gathered data. The method also includes causing display of a cluster map of the data structure, the cluster map comprising a plurality of clusters, each cluster of the plurality of clusters comprising a plurality of nodes, each node of the plurality of nodes comprising a plurality of pods, each pod of the plurality of pods comprising a plurality of containers. The method also includes providing a status for each node, each pod, and each container of each cluster. The method also includes causing display of analysis of each cluster of the cluster map, the analysis comprising granular information for each cluster.

Abstract: Techniques are disclosed relating to application verification. In various embodiments, a computing device includes a secure circuit configured to maintain a plurality of cryptographic keys of the computing device. In such an embodiment, the computing device receives, from an application, a request for an attestation usable to confirm an integrity of the application, instructs the secure circuit to use one of the plurality of cryptographic keys to supply the attestation for the application, and provides the attestation to a remote computing system in communication with the application. In some embodiments, the secure circuit is configured to verify received metadata pertaining to the identity of the application and use the cryptographic key to generate the attestation indicative of the identity of the application.

Abstract: Provided herein are antisense oligonucleotides and prophylactic and therapeutic methods featuring such oligonucleotides. These oligonucleotides and methods are useful for treating or preventing ataxia telangiectasia in a subject. Specifically, the disclosure provides antisense nucleobase oligomers each comprising (8-40) nucleobases, wherein at least 90% of said nucleobases or more than (8) consecutive nucleobases of the oligomer are complementary to a nucleic acid sequence in an Ataxia-Telangiectasia Mutated (ATM) allele comprising a mutation associated with aberrant splicing.

Abstract: Data analytics systems and methods are disclosed herein. A parser can parse reference data from various data sources to store in a data structure. An uploader can receive study data designated by a researcher and store the study data in the data structure. A matcher can compare analyte nameset data in the study data with analyte nameset data from the reference data to generate one or more links each correlating an instance of an analyte in the study data with an instance of that analyte in the reference data. Library overlays each include one or more modules to access reference data to generate organized associations of reference data. A calculation engine can receive a selection of one or more library overlay(s) and manipulate the reference data and study data according to the organized associations of the selected library overlay(s) to generate configured data stored in a collection of data caches for presentation to a researcher via a user interface.

Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

Abstract: Data analytics systems and methods are disclosed herein. A parser can parse reference data from various data sources to store in a data structure. An uploader can receive study data designated by a researcher and store the study data in the data structure. A matcher can compare analyte nameset data in the study data with analyte nameset data from the reference data to generate one or more links each correlating an instance of an analyte in the study data with an instance of that analyte in the reference data. Library overlays each include one or more modules to access reference data to generate organized associations of reference data. A calculation engine can receive a selection of one or more library overlay(s) and manipulate the reference data and study data according to the organized associations of the selected library overlay(s) to generate configured data stored in a collection of data caches for presentation to a researcher via a user interface.

Abstract: A surge protection device for providing bidirectional detections of one or more surge events. The device has low dynamic resistance during a surge protection mode, and it conducts ultra-low leakage current outside of the surge protection mode. In one implementation, the device includes first and second power transistors, a sensing circuit, and a driver circuit. The first power transistor includes a first source terminal that is coupled to the substrate, and the second power transistor includes a second source terminal that is coupled to the substrate. The sensing circuit is configured to detect a voltage of the first pin relative to the second pin and generate a sense signal when the voltage exceeds a threshold. The driver circuit is configured to generate a driver signal based on the sense signal and output the driver signal to at least one of the first or second gate terminal.

Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

Abstract: Data analytics systems and methods are disclosed herein. A parser can parse reference data from various data sources to store in a data structure. An uploader can receive study data designated by a researcher and store the study data in the data structure. A matcher can compare analyte nameset data in the study data with analyte nameset data from the reference data to generate one or more links each correlating an instance of an analyte in the study data with an instance of that analyte in the reference data. Library overlays each include one or more modules to access reference data to generate organized associations of reference data. A calculation engine can receive a selection of one or more library overlay(s) and manipulate the reference data and study data according to the organized associations of the selected library overlay(s) to generate configured data stored in a collection of data caches for presentation to a researcher via a user interface.

Abstract: In described examples, a power interface subsystem includes power transistors, each having: a conduction path coupled between a battery terminal and an accessory terminal; and a control terminal. A differential amplifier has: a first input coupled to the battery terminal; a second input coupled to the accessory terminal; and an output node. An offset voltage source is coupled to cause an offset of a selected polarity at one of the inputs to the differential amplifier. The offset has a first polarity in a first operating mode and a second polarity in a second operating mode. Gate control circuitry is coupled to apply a control level at the control terminal(s) of selected one(s) of the power transistors responsive to a voltage at the output node, and to apply an off-state control level to the control terminal(s) of unselected one(s) of the power transistors.

Abstract: The side profile of a hard drive assembly may be configured with one or more open areas to allow cooling air to pass side-to-side through a lateral flow channel provided by a cavity defined in the base portion of the hard drive assembly. Corresponding and complementary open areas may be also be defined in mating drive carrier assembly side components to allow passage of lateral side-to-side cooling air through the base portion flow channel of a hard drive assembled to the drive carrier assembly to form a mountable hard drive system that is installed into a storage enclosure. The at least partially aligned open flow areas of the assembled hard dive assembly and drive carrier assembly may cooperate to reduce air flow impedance across multiple rows of hard drive systems through a storage enclosure.

Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

Abstract: A sensor assembly for attachment underneath a screen of a combine harvester is provided with a plurality of sensor units having sensor elements, a plurality of which sensor units are arranged one behind the other within a hollow profile which extends in the longitudinal direction of the screen.

Abstract: A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

Abstract: Techniques are disclosed relating to application verification. In various embodiments, a computing device includes a secure circuit configured to maintain a plurality of cryptographic keys of the computing device. In such an embodiment, the computing device receives, from an application, a request for an attestation usable to confirm an integrity of the application, instructs the secure circuit to use one of the plurality of cryptographic keys to supply the attestation for the application, and provides the attestation to a remote computing system in communication with the application. In some embodiments, the secure circuit is configured to verify received metadata pertaining to the identity of the application and use the cryptographic key to generate the attestation indicative of the identity of the application.