Patents by Inventor Wade W. Grabow

Wade W. Grabow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Co-transcriptional assembly of modified RNA nanoparticles
    Patent number: 9719084
    Abstract: A method is provided for generating RNA nanoparticles having modified nucleotides and/or having increased nuclease resistance where the RNA nanoparticles are formed cotranscriptionally by T7 RNA polymerase in the presence of manganese ions.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: August 1, 2017
    Assignees: The United States of America, as represented by the Secretary, Department of Health & Human Services, The Regents of the University of California
    Inventors: Bruce A. Shapiro, Kirill A. Afonin, Maria L. Kireeva, Mikhail Kashlev, Luc Jaeger, Wade W. Grabow
  • CO-TRANSCRIPTIONAL ASSEMBLY OF MODIFIED RNA NANOPARTICLES
    Publication number: 20150203842
    Abstract: A method is provided for generating RNA nanoparticles having modified nucleotides and/or having increased nuclease resistance where the RNA nanoparticles are formed cotranscriptionally by T7 RNA polymerase in the presence of manganese ions.
    Type: Application
    Filed: September 6, 2013
    Publication date: July 23, 2015
    Inventors: Bruce A. Shapiro, Kirill A. Afonin, Maria L. Kireeva, Mikhail Kashlev, Luc Jaeger, Wade W. Grabow