Abstract: An ultrasound device is provided for imaging an anatomical region. The ultrasound device includes an ultrasound probe (288) having a medical instrument (202) in communication therewith, and an ultrasound sensor (279) mounted on the medical instrument. The ultrasound device further includes a hardware processor (214) configured to render a Region Of Interest (ROI) relative to a tip of the medical instrument on an ultrasound image displayed on a display device, and automatically and selectively perform a ROI refinement by positioning a displayed portion of the scanned image such that the ROI is located in a preferred specific region of the displayed portion of the scanned image. The displayed portion of the scanned image is a selectively magnifiable area within an area of the anatomical region including the medical instrument and spanned by the ultrasound scan line pattern.