Patents by Inventor Wafik El-Deiry

Wafik El-Deiry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular beacons, methods and kits for detecting DNA damage response
    Publication number: 20070178485
    Abstract: This invention relates to embodiment to a molecular beacon, methods and kits for the detection of expression of p21(Waf1/Cip1), in response to chemotherapy. Specifically, the introduction of a phosphorothioate-modified p21-beacon by transfection in human tumor cells yields increased signal in a dose dependent manner.
    Type: Application
    Filed: September 1, 2006
    Publication date: August 2, 2007
    Inventors: Wafik El-Deiry, Rishita Shah
  • P21.sup.WAF1 derivatives and diagnostic methods
    Patent number: 5871968
    Abstract: The striking compartmentalization of p21.sup.WAF1 expression found in normal tissues is completely abrogated in neoplastic tissues. Methods are provided for using p21.sup.WAF1 expression as a tool to assess neoplasia and to discover new drugs. A truncated p21.sup.WAF1 protein is more active than full-length p21.sup.WAF1 protein in inhibiting tumor cell growth.
    Type: Grant
    Filed: February 5, 1997
    Date of Patent: February 16, 1999
    Assignee: The Johns Hopkins University
    Inventors: Kenneth W. Kinzler, Wafik El-Deiry, Bert Vogelstein
  • P21WAF1 derivatives and diagnostic methods
    Patent number: 5807692
    Abstract: The striking compartmentalization of p21.sup.WAF1 expression found in normal tissues is completely abrogated in neoplastic tissues. Methods are provided for using p21.sup.WAF1 expression as a tool to assess neoplasia and to discover new drugs. A truncated p21.sup.WAF1 protein is more active than full-length p21.sup.WAF1 protein in inhibiting tumor cell growth.
    Type: Grant
    Filed: December 18, 1995
    Date of Patent: September 15, 1998
    Assignee: The Johns Hopkins University
    Inventors: Kenneth W. Kinzler, Wafik El-Deiry, Bert Vogelstein