Abstract: An automated sterile compounding dose preparation station is disclosed herein. The preparation station determines availability data based on a current working status and queued dose orders and transmits the availability data to an application server. The preparation station receives, from the application server, an inventory dose order that does not correspond to a patient when the application server determines the automated sterile compounding dose preparation station has availability based on the availability date. The inventory dose order specifies a sterile compounded medication product that is suitable for administration by intravenous introduction to a human. The preparation station prepares an inventory dose corresponding to the inventory dose order, determines an expiration date of the inventory dose, and causes a printer to print a label for the inventory dose. The label indicates that the inventory dose is to be stored and includes information indicative of the expiration date of the inventory dose.

Abstract: Embodiments of stable topical compositions for administering fenoldopam (compound (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed for immediate or continued slow release administration, over prolonged periods of time with safe minimal systemic exposure of fenoldopam (reducing the risk for lowering blood pressure). The compositions include those compositions that increase the stability and skin absorption of the drug, particularly anhydrous semi-solid compositions and creams. This is accomplished by incorporating fenoldopam in soluble or dispersed form into semi-solid compositions like ointments or anhydrous gels that are not irritative. Embodiments of methods for using the topical compositions in the treatment of dermatological disorders including psoriasis, alopecia atopic dermatitis and vitiligo are disclosed.

Abstract: Embodiments of stable topical compositions for administering fenoldopam (compound (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed for immediate or continued slow release administration, over prolonged periods of time with safe minimal systemic exposure of fenoldopam (reducing the risk for lowering blood pressure). The compositions include those compositions that increase the stability and skin absorption of the drug, particularly anhydrous semi-solid compositions and creams. This is accomplished by incorporating fenoldopam in soluble or dispersed form into semi-solid compositions like ointments or anhydrous gels that are not irritative. Embodiments of methods for using the topical compositions in the treatment of dermatological disorders including psoriasis, alopecia atopic dermatitis and vitiligo are disclosed.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a medication compounding workstation configured to receive a medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a compounded medication dose specified by the medication dose order. The example workstation is also configured to display, on a display screen to a pharmacy operator, information related to the set of steps for preparing the compounded medication dose and receive input related to the preparation of the compounded medication dose including at least medication information from at least one source medication container. The workstation verifies completion for each step for preparing the compounded medication dose.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a batch compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare compounded medication doses specified by the batch compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the compounded medication doses and receive input related to the preparation of the compounded medication doses including at least medication information scanned from at least one source medication container and a digital image from a digital camera. The workstation verifies completion for each step before allowing the pharmacy operator to move to a next step to prepare the compounded medication doses.

Abstract: A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

Abstract: A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

Abstract: A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract: A centralized system and method for preparing and managing medications prepared in anticipation of use for at a remote location. An order processing server receives a patient-specific dose order from a remote site connected to a remote location through a network. A dose preparation station prepares doses in anticipation of use, information about which is stored in a database. The dose preparation stations can be instructed to prepare certain non-patient-specific doses based on the availability of the stations or the patient-specific dose orders received from the remote site. An application server matches any received dose order with one of the prepared inventory doses based on the stored inventory data, and associates the patient-specific dose order with the inventory dose order. The inventory data is managed to reflect the association of the patient-specific dose order with the matched inventory dose, and the association can be stored in the database.

Abstract: A system for preparing compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a batch compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare compounded medication doses specified by the batch compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the compounded medication doses and receive input related to the preparation of the compounded medication doses including at least medication information scanned from at least one source medication container and a digital image from a digital camera. The workstation verifies completion for each step before allowing the pharmacy operator to move to a next step to prepare the compounded medication doses.

Abstract: Embodiments of stable topical compositions for administering fenoldopam (compound (I) or a pharmaceutically acceptable salt or solvate thereof are disclosed for immediate or continued slow release administration, over prolonged periods of time with safe minimal systemic exposure of fenoldopam (reducing the risk for lowering blood pressure). The compositions include those compositions that increase the stability and skin absorption of the drug, particularly anhydrous semi-solid compositions and creams. This is accomplished by incorporating fenoldopam in soluble or dispersed form into semi-solid compositions like ointments or anhydrous gels that are not irritative. Embodiments of methods for using the topical compositions in the treatment of dermatological disorders including psoriasis, alopecia atopic dermatitis and vitiligo are disclosed.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract: A system for preparing patient-specific compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a patient-specific compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a patient-specific compounded medication dose specified by the patient-specific compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the patient-specific compounded medication dose and receive input related to the preparation of the patient-specific compounded medication dose including at least medication information scanned from at least one source medication container and a digital image from a digital camera.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.

Abstract: A system for preparing and managing patient-specific dose orders includes an order processing server configured to receive the patient-specific dose orders, define a queue of dose orders and distribute the dose orders to at least one dose preparation station. The dose preparation station is in bi-directional communication with the order processing server and has an interface for providing an operator with a protocol associated with each received drug order and specifying a set of steps to fill the drug order. Steps to fill the drug order are captured at the station and a display, positionable independent of the station outputs the dose order queue and metrics concerning activity at the dose preparation station. Systems for preparing patient-specific doses and a method for telepharmacy in which data captured while following the protocol are provided to a remote site for review and approval by a pharmacist.

Abstract: A system for preparing patient-specific compounded medication doses is disclosed. The system includes a computerized medication compounding workstation configured to receive a patient-specific compounded medication dose order over a network and retrieve an electronically stored protocol having a set of steps to prepare a patient-specific compounded medication dose specified by the patient-specific compounded medication dose order. The example workstation is also configured to display, on a graphical user interface to a pharmacy operator, information related to the set of steps for preparing the patient-specific compounded medication dose and receive input related to the preparation of the patient-specific compounded medication dose including at least medication information scanned from at least one source medication container and a digital image from a digital camera.

Abstract: A spray drier system is provided for spray drying a liquid sample such as blood plasma. The spray drier system may include a spray drier device adapted to couple with a spray drier assembly. The assembly may include an enclosure mounted to a frame. The assembly may receive a flow of drying gas which is directed by the enclosure shape towards a spray drying head mounted within the enclosure to the frame. Flows of a liquid sample may be further received by the head, which aerosolizes the liquid sample. Aerosolized liquid sample and drying air may be mixed within a drying chamber of the enclosure to produce dried sample and humid air. The dried sample and humid air may also be separated in a collection chamber of the enclosure, with the humid air exhausted from the enclosure.

Abstract: Disclosed are methods of spray drying blood plasma using a two-step drying process.

Abstract: An automated medication preparation system for preparing a prescribed dosage of medication in a drug delivery device includes a plurality of stations for receiving, handling and processing the drug delivery device so that the prescribed dosage of medication is delivered to the drug delivery device and a transporting device that receives and holds more than one drug delivery device and moves the drug delivery devices in a controlled manner from one station to another station. The system is configured so that two or more separate drug delivery devices can be acted upon at the same time.