Patents by Inventor Wai Kwok Wong

Wai Kwok Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230051807
    Abstract: Porphyrin photosensitizers including 5,15-di(naphthalimide) moieties useful for photocatalytic hydrogen evolution, compositions including the same, and methods of use thereof.
    Type: Application
    Filed: June 28, 2022
    Publication date: February 16, 2023
    Inventors: Xunjin ZHU, Govardhana Babu BODEDLA, Wai-Kwok WONG, Wai-Yeung WONG
  • Patent number: 11491224
    Abstract: Provided herein are porphyrinato-lanthanide complexes useful as theranostic agents and methods of preparation and use thereof. The porphyrinato-lanthanide complexes are useful in the treatment and imaging of cancer.
    Type: Grant
    Filed: April 2, 2019
    Date of Patent: November 8, 2022
    Assignee: Hong Kong Baptist University
    Inventors: Ka Leung Wong, Wai Kwok Wong, Ho Fai Chau
  • Publication number: 20190298832
    Abstract: Provided herein are porphyrinato-lanthanide complexes useful as theranostic agents and methods of preparation and use thereof. The porphyrinato-lanthanide complexes are useful in the treatment and imaging of cancer.
    Type: Application
    Filed: April 2, 2019
    Publication date: October 3, 2019
    Inventors: Ka Leung WONG, Wai Kwok WONG, Ho Fai CHAU
  • Patent number: 10369221
    Abstract: The present disclosure relates to porphyrin containing carbon quantum dots useful for bioimaging and/or phytodynamic therapy.
    Type: Grant
    Filed: November 8, 2017
    Date of Patent: August 6, 2019
    Assignee: Hong Kong Baptist University
    Inventors: Xunjin Zhu, Wai Kwok Wong, Fengshou Wu
  • Patent number: 10236457
    Abstract: The present disclosure relates to porphyrin small molecules that can be represented by, e.g., a compound of Formula IV designed and synthesized for bulk heterojunction (BHJ) organic solar cells (OSCs). Provided are synthesized materials with strong and ordered self-assembly property, leading to form bi-continuous, interpenetrating networks which are required for efficient charge separation and transport in organic solar cells. The power conversion efficiency (PCE) of the solar cells devices based on the embodiments of the present disclosure have the highest PCE among the solution-processed BHJ solar cell based on porphyrin small molecules to date.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: March 19, 2019
    Assignee: Hong Kong Baptist University
    Inventors: Xunjin Zhu, Song Chen, Wai Yeung Wong, Wai Kwok Wong
  • Publication number: 20180125976
    Abstract: The present disclosure relates to porphyrin containing carbon quantum dots useful for bioimaging and/or phytodynamic therapy.
    Type: Application
    Filed: November 8, 2017
    Publication date: May 10, 2018
    Inventors: Xunjin ZHU, Wai Kwok WONG, Fengshou WU
  • Publication number: 20180006248
    Abstract: The present disclosure relates to porphyrin small molecules substitutes designed and synthesized for bulk heterojunction (BHJ) organic solar cells (OSCs). Provided are synthesized materials with strong and ordered self-assembly property, leading to form bi-continuous, interpenetrating networks which are required for efficient charge separation and transport in organic solar cells. The power conversion efficiency (PCE) of the solar cells devices based on the embodiments of the present disclosure have the highest PCE among the solution-processed BHJ solar cell based on porphyrin small molecules up to date.
    Type: Application
    Filed: June 28, 2017
    Publication date: January 4, 2018
    Inventors: Xunjin ZHU, Song CHEN, Wai Yeung WONG, Wai Kwok WONG
  • Patent number: 9840522
    Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: December 12, 2017
    Assignee: Hong Kong Baptist University
    Inventors: Ka Leung Wong, Wai Kwok Wong
  • Publication number: 20170107238
    Abstract: The present invention relates to a new generation of PDT agents based on porphyrin-lanthanide complexes with specific functional groups which can specifically localize on particular tumors, and their PDT processes can be monitored via NIR emission from erbium. In particular, the present invention provides a multi-modal lanthanide-porphyrin PDT agent (Er—R3) that are capable of killing the bladder tumor cells selectivity via 1O2 from porphyrin moiety and affording the fluorescence imaging simultaneously upon Er—R3 binding with the integrin ?v?3 isoform in bladder cancer cells.
    Type: Application
    Filed: November 15, 2016
    Publication date: April 20, 2017
    Inventors: Ka Leung WONG, Wai Kwok WONG
  • Patent number: 9522925
    Abstract: The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd—N) with a molecular formula of: which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species—singlet oxygen—prior to due excitation. The present invention also provides the use of Gd—N as a tumor selective PDT photosensitizer modality.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: December 20, 2016
    Assignee: Hong Kong Baptist University
    Inventors: Ka-Leung Wong, Wai-Kwok Wong, Rongfeng Lan, Tao Zhang
  • Publication number: 20160130284
    Abstract: The present invention discloses a new modality of photodynamic therapy (PDT) through the design of the present invention's truly dual-functional—PDT and imaging—gadolinium complex (Gd-N) with a molecular formula of: which can target cancer, cells specifically. The present invention provides a PDT drug that can specifically localize on the anionic cell membrane of cancer cells in which its laser-excited photoemission signal can be monitored without triggering the phototoxic generation of reactive oxygen species—singlet oxygen—prior to due excitation. The present invention also provides the use of Gd-N as a tumor selective PDT photosensitizer modality.
    Type: Application
    Filed: November 5, 2015
    Publication date: May 12, 2016
    Inventors: Ka-Leung WONG, Wai-Kwok WONG, Rongfeng LAN, Tao ZHANG
  • Publication number: 20120281410
    Abstract: An illuminating device includes an illuminator with an illuminating mechanism. The illuminating mechanism includes several LEDs. The illuminating device is reversibly fixed by at least one holding device. The holding device includes a guiding device and a wing shaped unit. The wing shaped unit can be fixed and turned on the guiding device and can be guided along the guiding device. The holding device includes an unfolding mechanism. The wing shaped unit is oriented transverse to the guiding device by arranging the unfolding mechanism. The wing shaped unit is completely unfolded at a light emitting side. When the wing shaped unit is guided away from the light emitting side, the wing shaped unit is reversibly folded via a physical contact with a folding mechanism. The span of the light emitting side is greater than the span with the wing shaped unit being folded.
    Type: Application
    Filed: December 8, 2010
    Publication date: November 8, 2012
    Applicant: TRAXON TECHNOLOGIES LTD.
    Inventor: Wai Kwok Wong
  • Patent number: 6869814
    Abstract: A light emitting diode (LED), and a method for producing the same. The LED includes a substrate that may be made of silicon, a first conductive layer on one side, and a porous insulating layer on the opposite side. The insulating layer defines microcavities therein, the microcavities having sharp tips on their inner surfaces. The microcavities have gas inside. A second conductive layer is disposed over the insulating layer. When an electrical potential is applied between the conductive layers, the gas-filled microcavities act as plasma discharge lamps, emitting light. The light may be in the ultraviolet portion of the spectrum. The method includes etching a substrate to produce a porous insulating layer on one side, depositing a first conductive layer on the opposite side, and depositing a second conductive layer over the insulating layer. The microcavities in the insulating layer are then filled with gas.
    Type: Grant
    Filed: May 21, 2004
    Date of Patent: March 22, 2005
    Inventors: Kok Wai Cheah, Wai Kwok Wong, Hoi Lam Tam
  • Publication number: 20040211973
    Abstract: A light emitting diode (LED), and a method for producing the same. The LED includes a substrate that may be made of silicon, a first conductive layer on one side, and a porous insulating layer on the opposite side. The insulating layer defines microcavities therein, the microcavities having sharp tips on their inner surfaces. The microcavities have gas inside. A second conductive layer is disposed over the insulating layer. When an electrical potential is applied between the conductive layers, the gas-filled microcavities act as plasma discharge lamps, emitting light. The light may be in the ultraviolet portion of the spectrum. The method includes etching a substrate to produce a porous insulating layer on one side, depositing a first conductive layer on the opposite side, and depositing a second conductive layer over the insulating layer. The microcavities in the insulating layer are then filled with gas.
    Type: Application
    Filed: May 21, 2004
    Publication date: October 28, 2004
    Inventors: Kok Wai Cheah, Wai Kwok Wong, Hoi Lam Tam
  • Patent number: 6759686
    Abstract: A light emitting diode (LED), and a method for producing the same. The LED includes a substrate that may be made of silicon, a first conductive layer on one side, and a porous insulating layer on the opposite side. The insulating layer defines microcavities therein, the microcavities having sharp tips on their inner surfaces. The microcavities have gas inside. A second conductive layer is disposed over the insulating layer. When an electrical potential is applied between the conductive layers, the gas-filled microcavities act as plasma discharge lamps, emitting light. The light may be in the ultraviolet portion of the spectrum. The method includes etching a substrate to produce a porous insulating layer on one side, depositing a first conductive layer on the opposite side, and depositing a second conductive layer over the insulating layer. The microcavities in the insulating layer are then filled with gas.
    Type: Grant
    Filed: March 14, 2003
    Date of Patent: July 6, 2004
    Inventors: Kok Wai Cheah, Wai Kwok Wong, Hoi Lam Tam
  • Publication number: 20030227031
    Abstract: A light emitting diode (LED), and a method for producing the same. The LED includes a substrate that may be made of silicon, a first conductive layer on one side, and a porous insulating layer on the opposite side. The insulating layer defines microcavities therein, the microcavities having sharp tips on their inner surfaces. The microcavities have gas inside. A second conductive layer is disposed over the insulating layer. When an electrical potential is applied between the conductive layers, the gas-filled microcavities act as plasma discharge lamps, emitting light. The light may be in the ultraviolet portion of the spectrum. The method includes etching a substrate to produce a porous insulating layer on one side, depositing a first conductive layer on the opposite side, and depositing a second conductive layer over the insulating layer. The microcavities in the insulating layer are then filled with gas.
    Type: Application
    Filed: March 14, 2003
    Publication date: December 11, 2003
    Inventors: Kok Wai Cheah, Wai Kwok Wong, Hoi Lam Tam
  • Patent number: 6056868
    Abstract: The present invention discloses the doping of rare earth elements into porous silicon, resulting in enhancement of luminescence. The doping is an electro-chemical process using constant voltage bias across the two electrodes in which the anode is porous silicon and the cathode is platinum. The doping process involves a well-defined solution of electrolytes that controls the conductivity of the solution, and set values of constant voltages that selectively allow the desired rare earth elements being doped into porous silicon.
    Type: Grant
    Filed: May 22, 1998
    Date of Patent: May 2, 2000
    Inventors: Kok Wei Cheah, Wai Kwok Wong, Meng Lian Gong, Wan Han Zheng