Patents by Inventor Wai-Nang P. Lee

Wai-Nang P. Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of isotope labeling and determining protein synthesis, quantitation and protein expression
    Patent number: 8574543
    Abstract: A method including isotope labeling of a newly synthesized protein in a sufficient quantity such that a newly synthesized protein spectra and the pre-existing protein spectra are sufficiently separated. A further method including determining a ratio of a new and a pre-existing protein from mass spectra obtained by using mass spectrometry. In this method a resultant spectrum may be presented as integrated peak heights for a corresponding mass to charge ratio in the “centroid” mode.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: November 5, 2013
    Assignee: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center
    Inventors: Wai-Nang P. Lee, Guishan Xiao
  • METHOD OF ISOTOPE LABELING AND DETERMINING PROTEIN SYNTHESIS, QUANTITATION AND PROTEIN EXPRESSION
    Publication number: 20090176199
    Abstract: A method including isotope labeling of a newly synthesized protein in a sufficient quantity such that a newly synthesized protein spectra and the pre-existing protein spectra are sufficiently separated. A further method including determining a ratio of a new and a pre-existing protein from mass spectra obtained by using mass spectrometry. In this method a resultant spectrum may be presented as integrated peak heights for a corresponding mass to charge ratio in the “centroid” mode.
    Type: Application
    Filed: December 11, 2008
    Publication date: July 9, 2009
    Inventors: Wai-Nang P. Lee, Guishan Xiao
  • Coincidence counting emission tomographic probe: method and apparatus
    Patent number: 4682604
    Abstract: This invention comprises a method and apparatus for measuring both the absolute levels and variations of radioactivity emitted following administration of suitable radioisotopes during a test period by selected organs. Miniaturized radiation detectors for measuring two different types of radiation, such as gamma rays and photons, for example, are modified by the addition of mutual overlap coincidence units, scalers, single channel analyzers and time-gates. The individual detector units are appropriately arranged to form a probe or collar in either a strip or a checkerboard configuration, extending around the neck to study the thyroid gland or other gland organ to be analyzed. The associated electronic architecture is appropriately designed in either simplex or multiplex circuit patterns.
    Type: Grant
    Filed: February 25, 1985
    Date of Patent: July 28, 1987
    Assignee: The Regents of the University of California
    Inventors: Alain L. Fymat, Wai-Nang P. Lee, Moses A. Greenfield
  • Method for evaluating thyroid function
    Patent number: 4478945
    Abstract: Clinical method for evaulating thyrometabolic function by determination of clinically important thyroxine concentrations and thyroxine binding protein capacities in plasma.The method employs a competitive binding technique for determining free thyroxine concentration and thyroxine binding capacity for plasma having a known total thyroxine concentration.
    Type: Grant
    Filed: July 28, 1981
    Date of Patent: October 23, 1984
    Inventors: Wai-Nang P. Lee, Michael D. Harpen, Jeffry A. Siegel