Abstract: Provided herein are polypeptides including an amino acid sequence having at least 70% sequence identity with an Isthmin 1 (ISM1) protein or a GRP78-activating fragment thereof, as well as expressible nucleic acids encoding said polypeptides. Uses of such agents, as well as methods for inducing apoptosis in alveolar macrophages and/or for treating, ameliorating, or preventing inflammation or lung disease such as chronic obstructive pulmonary disease (COPD), emphysema, asthma, acute lung injury (ALI), lung fibrosis, and/or acute respiratory distress syndrome.

Abstract: An electronic device may be provided with wireless circuitry. The wireless circuitry may include one or more antennas. The antennas may include phased antenna arrays each of which includes multiple antenna elements. Phased antenna arrays may be formed from printed circuit board Yagi antennas or other antennas. A millimeter wave transceiver may use the antennas to transmit and receive wireless signals. The antennas may be mounted at the corners of an electronic device housing or elsewhere in an electronic device. An electronic device housing may be formed from metal and may have an opening filled with dielectric. The antennas may be aligned with portions of the dielectric. Printed circuit board antennas may have reflectors, radiators, and directors. The reflectors, radiators, and directors may be arranged to align radiation patterns for the antennas with the plastic-filled slots or other dielectric regions in the metal housing.

Abstract: An electronic device may be provided with wireless circuitry. The wireless circuitry may include one or more antennas. The antennas may include phased antenna arrays each of which includes multiple antenna elements. Phased antenna arrays may be formed from printed circuit board Yagi antennas or other antennas. A millimeter wave transceiver may use the antennas to transmit and receive wireless signals. The antennas may be mounted at the corners of an electronic device housing or elsewhere in an electronic device. An electronic device housing may be formed from metal and may have an opening filled with dielectric. The antennas may be aligned with portions of the dielectric. Printed circuit board antennas may have reflectors, radiators, and directors. The reflectors, radiators, and directors may be arranged to align radiation patterns for the antennas with the plastic-filled slots or other dielectric regions in the metal housing.

Abstract: A test system may include a wireless test chamber with metal walls lined with pyramidal absorbers. A trapdoor may be provided in a wall opening to accommodate a robotic arm. The robotic arm may have grippers that grip a device under test or a support structure that is supporting a device under test. The robotic arm may move the device under test to a docking station for automatic battery charging during testing. When it is desired to perform wireless tests on a device under test, the robotic arm may move the device under test through the trapdoor into an interior portion of the test chamber. A turntable and movable test antenna may be used to rotate the device under test while varying angular orientations between test antenna and device under test. Emitted radiation levels can be measured using a liquid filled phantom and test probe on a robotic arm.

Abstract: A test system may include a wireless test chamber with metal walls lined with pyramidal absorbers. A trapdoor may be provided in a wall opening to accommodate a robotic arm. The robotic arm may have grippers that grip a device under test or a support structure that is supporting a device under test. The robotic arm may move the device under test to a docking station for automatic battery charging during testing. When it is desired to perform wireless tests on a device under test, the robotic arm may move the device under test through the trapdoor into an interior portion of the test chamber. A turntable and movable test antenna may be used to rotate the device under test while varying angular orientations between test antenna and device under test. Emitted radiation levels can be measured using a liquid filled phantom and test probe on a robotic arm.

Abstract: Artesunate is a derivative of artemisinin isolated from a Chinese herb Artemisia annua L. It is used clinically for the treatment of malaria. We investigated potential anti-inflammatory actions of artemisinin derivatives. artemisinin derivatives significantly inhibited OVA-induced signs, symptoms and parameter of airway disorders Taken together, our results clearly demonstrate anti-inflammatory effects of artemisinin derivatives. Artemisinin derivatives can be used to complement or to replace oral steroids during asthma exacerbation treatment. Further artemisinin derivatives can be used as an anti-inflammatory agent for controlling airway disorders.

Abstract: Artesunate is a derivative of artemisinin isolated from a Chinese herb Artemisia annua L. It is used clinically for the treatment of malaria. We investigated potential anti-inflammatory actions of artemisinin derivatives. artemisinin derivatives significantly inhibited OVA-induced signs, symptoms and parameter of airway disorders Taken together, our results clearly demonstrate anti-inflammatory effects of artemisinin derivatives. Artemisinin derivatives can be used to complement or to replace oral steroids during asthma exacerbation treatment. Further artemisinin derivatives can be used as an anti-inflammatory agent for controlling airway disorders.

Abstract: We describe for the first time that andrographolide derivatives such as DDAG effectively reduced OVA-induced inflammatory cell recruitment into BAL fluid, IL-4, IL-5, IL-13 and eotaxin production, serum IgE synthesis, pulmonary eosinophilia, mucus hypersecretion and AHR in a mouse asthma model potentially via inhibition of NF-?B activity. Moreover, low dose of DDAG and glucocorticoid combination treatment synergistically attenuate inflammation in mouse asthma model. These findings support a therapeutic value for DDAG in the treatment of asthma.

Abstract: Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for decreasing airway hyperresponsiveness or airway inflammation in an animal are also provided.

Abstract: An improved image processing system is provided which receives image data at a computer and transfers that image data to a work flow server for image processing and document distribution. The system uses a work flow web application computer program that receives image data from a scanner, transfers that image data via a native interface or a driver on a client computer to a browser on the client computer, and then sends the data to a network document distribution server which is addressed from the client computer using URL's.

Abstract: Compositions and methods for the treatment and diagnosis of diseases or conditions amenable to treatment through modulation of expression of a gene encoding a p38 mitogen-activated protein kinase (p38 MAPK) are provided. Methods for the treatment and diagnosis of diseases or conditions associated with aberrant expression of one or more p38 MAPKs are also provided.

Abstract: This invention provides a toy vehicle incorporating actuators made from a shape memory alloy material. These actuators may be in the form of a spring, wire or similar form that has a mechanical response upon the application or removal of heat. In particular, wires may be connected about hinges for doors, hoods, convertible roofs and other such items which, upon the application of heat to the wire of shape memory ally, causes contraction of the wire and rotation about the hinged joint of the body part. As such shape memory ally actuators are generally only operable in a single direction, they may be provided in pairs or in opposition to another biasing means to cause the opposed rotation about the joint when desired. The preferred source of heat to the shape memory alloy actuators is through the provision of electrical energy to the wire to create heat through the resistance of the shape memory alloy actuator itself.

Abstract: This invention provides a toy vehicle incorporating actuators made from a shape memory alloy material. These actuators may be in the form of a spring, wire or similar form that has a mechanical response upon the application or removal of heat. In particular, wires may be connected about hinges for doors, hoods, convertible roofs and other such items which, upon the application of heat to the wire of shape memory alloy, causes contraction of the wire and rotation about the hinged joint of the body part. As such shape memory alloy actuators are generally only operably in a single direction, they may be provided in pairs or in opposition to another biasing means to cause the opposed rotation about the joint when desired. The preferred source of heat to the shape memory alloy actuators is through the provision of electrical energy to the wire to create heat through the resistance of the shape memory alloy actuator itself.