Patents by Inventor Wai Yip Lee

Wai Yip Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FATTY ACID CONJUGATED NANOPARTICLES AND USES THEREOF
    Publication number: 20190029970
    Abstract: The present invention provides fatty acid-conjugated nanoparticles and methods of making and using the same. Methods for improving delivery of therapeutic agents (e.g., drugs) contained within the fatty acid conjugated nanoparticles to the central nervous system (e.g., across the blood brain barrier) are disclosed.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 31, 2019
    Inventors: Wai Yip LEE, Ho Yin Li
  • Formulations of cyclopropanecarboxylic acid {2-[(1S)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1H-isoindol-4-yl}-amide
    Patent number: 9884042
    Abstract: Pharmaceutical compositions and single unit dosage forms of {2-[(IS)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1H-isoindol-4-yl}-amide, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate thereof, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer or an inflammatory disease.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: February 6, 2018
    Assignee: Celgene Corporation
    Inventors: Nathan Boersen, Wai Yip Lee, Ho-Wah Hui, Paul Kurtulik
  • ORALLY-DISSOLVING FILMS FOR DRUG DELIVERY THROUGH THE ORAL CAVITY
    Publication number: 20180000725
    Abstract: Orally dissolving films including a pharmaceutically active ingredient having a low bioavailability due to first-pass metabolism and/or low water solubility upon oral administration and a pharmaceutically acceptable excipient, and a medical application thereof.
    Type: Application
    Filed: June 13, 2017
    Publication date: January 4, 2018
    Inventors: Wai Yip LEE, Yuan FANG, Qingqing LI, Hao HAN, Ka Lun LAI
  • FORMULATIONS OF CYCLOPROPANECARBOXYLIC ACID -AMIDE
    Publication number: 20150190374
    Abstract: Pharmaceutical compositions and single unit dosage forms of {2-[(IS)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1H-isoindo1-4-yl}-amide, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate thereof, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer or an inflammatory disease.
    Type: Application
    Filed: September 13, 2012
    Publication date: July 9, 2015
    Inventors: Nathan Boersen, Wai Yip Lee, Ho-Wah Hui, Paul Kurtulik
  • Modified release famciclovir pharmaceutical compositions
    Publication number: 20090023754
    Abstract: A modified release pharmaceutical composition of famciclovir contains at least 60% by weight famciclovir with at least 5% by weight of a release retardant. Particularly useful as a release retardant include polymers, especially a mixture of polyvinyl acetate and polyvinylpyrrolidone. A method of making such pharmaceutical compositions using a extruder and a granulation method is particularly useful.
    Type: Application
    Filed: May 8, 2006
    Publication date: January 22, 2009
    Inventors: Wai Yip Lee, Shoufeng Li