Abstract: A TEE system that includes a first platform that runs a first TEE, a second platform that runs a second TEE, and a merging unit that is adapted to merge a first output from the first TEE of the first platform, with a second output from the second TEE of the second platform, so as to form an output of the TEE system. The first TEE and the second TEE are based on different implementations. In this way, the security of the system is improved, as a malicious actor even be able to access “t” machines, still would not be able to retrieve the secret unless there are multiple exploitable TEE vulnerabilities on all executing TEE platforms at the same time.

Abstract: A storage system includes a panel secured to a support surface and a storage container removably supported on the panel. The panel includes a plurality of cleats. The storage container includes a first container portion, a second container portion, and a support feature engageable with the cleats. The second container portion and the first container portion are pivotably movable between a closed position and an open position. The support feature includes a first partial mounting portion and a second partial mounting portion. The second partial mounting portion is movable between a stowed position and an extended position. The first partial mounting portion and the second partial mounting portion cooperate to provide a mounting interface to engage the cleats while the second partial mounting portion is in the extended position.

Abstract: A method for preparing a self-cleaning transparent thermal insulation nanocoating includes steps of (1) preparing an acidic aqueous solution, and adding polyoxyethylene dinonyl phenyl ether and graphene into the acidic aqueous solution; (2) preparing a transparent composite nanosol by adding titanate, zinc alkoxide, ytterbium alkoxide and siloxane into the acid aqueous solution through sol-gel reaction; (3) preparing a primary coating by spraying the transparent composite nanosol onto a glass surface; and (4) spraying a dilute alkaline solution onto the primary coating to condense and crosslink components in the primary coating, so that the self-cleaning transparent thermal insulation nanocoating is in-situ generated.

Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: Compounds and compositions, for example vardenafil, for treating diseases and/or conditions caused by, arising from, and/or associated with coronavirus in a subject, for example a subject infected with SARS-CoV-2 or other coronavirus. Combinations of agents useful for treating diseases and/or conditions caused by, arising from, and/or associated with coronavirus in a subject, for example, vardenafil and Remdesivir, are also provided.

Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: A computer implemented device is described that is adapted for improving memory efficiency for conducting machine learning on multi-dimensional vectors stored as specially configured data structures. The device includes network interfaces adapted for receiving data sets and communicating with data harvesting applications, as well as data storage and memory for storing the configured data structures. The multi-dimensional vectors and the system provide a data architecture that processes disparate data sets to programmatically extract features transformed from raw information, the extracted features stored in the form of data values suitable for conducting data approximations and neural network processing.

Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: The present invention provides a composition and method for preventing the growth of and/or treating cancerous tumors and/or delaying onset of cancer from tumor-initiating cells. The composition includes an effective amount of a compound of Formula (I) or Formula (II): or any pharmaceutically acceptable salt thereof. The composition is administered alone or in combination with one or more chemotherapeutic agents, biological agents and/or anticancer agents. The method may include administering the composition of the present invention with or without the chemotherapeutic, biological, or other cancer treatment agent to a subject in need thereof intravenously, parenterally, nasally, topically or locally, orally, or by liposome, implant or via vessel-targeted nanosuspension delivery.

Abstract: Molecularly imprinted polymers (MIPs) capable of binding acetate and other target molecules, processes for their production, pharmaceutical compositions comprising the MIPs, and methods of using the MIPs and pharmaceutical compositions for binding target molecules and for treating conditions associated with accumulation of acetate and other target molecules.

Abstract: Molecularly imprinted polymers (MIPs) capable of binding acetate and other target molecules, processes for their production, pharmaceutical compositions comprising the MIPs, and methods of using the MIPs and pharmaceutical compositions for binding target molecules and for treating conditions associated with accumulation of acetate and other target molecules.

Abstract: A computer implemented device is described that is adapted for improving memory efficiency for conducting machine learning on multi-dimensional vectors stored as specially configured data structures. The device includes network interfaces adapted for receiving data sets and communicating with data harvesting applications, as well as data storage and memory for storing the configured data structures. The multi-dimensional vectors and the system provide a data architecture that processes disparate data sets to programmatically extract features transformed from raw information, the extracted features stored in the form of data values suitable for conducting data approximations and neural network processing.

Abstract: The present invention provides fatty acid-conjugated nanoparticles and methods of making and using the same. Methods for improving delivery of therapeutic agents (e.g., drugs) contained within the fatty acid conjugated nanoparticles to the central nervous system (e.g., across the blood brain barrier) are disclosed.

Abstract: A system, method, and computer-readable medium for optimizing complex SQL statements using a region divided preferential SQL rewrite operation. The region divided preferential SQL rewrite operation makes it possible for a user to inference a machine SQL statement rewrite operation to optimize the SQL statement with more or less focus on different regions of the SQL. This operation combines the strength of using heuristic knowledge and understanding of data to rewrite the region of the SQL statement where the problem originates with the precision and efficiency of a machine SQL statement rewrite operation.

Abstract: A multi-ply shockproof, hygroscopic and breathable shoe pad includes, from bottom to top in succession: a support bottom layer (1), wherein a lower end face of the support bottom layer (1) is provided with a plurality of protruding portions (5), an upper end face of the support bottom layer (1) is provided with air holes (6), and the protruding portions (5) and the air holes (6) are alternately arranged; an elastic interlayer (2), wherein the elastic interlayer (2) is provided with air holes (6), and is coated with an antibacterial deodorization layer; a hygroscopic interlayer (3), wherein the hygroscopic interlayer (3) is provided with air holes (6), and is coated with an antibacterial deodorization layer; and a breathable waterproof layer (4) coated with an antibacterial deodorization layer; and the support bottom layer (1), the elastic interlayer (2), the hygroscopic interlayer (3), and the breathable waterproof layer (4) are successively bonded.

Abstract: Pharmaceutical compositions and single unit dosage forms of {2-[(IS)-1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-oxo-2,3-dihydro-1H-isoindol-4-yl}-amide, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate thereof, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer or an inflammatory disease.

Abstract: Orally dissolving films including a pharmaceutically active ingredient having a low bioavailability due to first-pass metabolism and/or low water solubility upon oral administration and a pharmaceutically acceptable excipient, and a medical application thereof.

Abstract: The present invention provides a new crystalline form of itraconazole as well as the method of making same.

Abstract: The present invention provides a new crystalline form of itraconazole as well as the method of making same.