Patents by Inventor Wain White

Wain White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MAP-2 as a determinant of metastatic potential
    Patent number: 6613534
    Abstract: The invention relates to detection of MAP-2 (microtubule associated protein-2) as a marker to determine the metastatic potential of a tumor, including tumors derived from the neural crest such as melanomas, gliomas, Schwanomas, chromocytomas and small cell lung cancer. In one aspect, the invention comprises a method for determining the metastatic potential of a tumor sample, wherein decreased levels of MAP-2 expression in a test sample relative to controls indicates that the sample has increased metastatic potential as compared to the control. In another aspect, the invention comprises a method to prevent tumor progression in metastatic melanoma by increasing levels of MAP-2 protein in cells.
    Type: Grant
    Filed: March 20, 2001
    Date of Patent: September 2, 2003
    Assignee: Wake Forest University Health Sciences
    Inventors: Vijayasaradhi Setaluri, Dong Fang, Wain White
  • MAP-2 as a determinant of metastatic potential
    Publication number: 20020192727
    Abstract: The invention relates to detection of MAP-2 (microtubule associated protein-2) as a marker to determine the metastatic potential of a tumor, including tumors derived from the neural crest such as melanomas, gliomas, Schwanomas, chromocytomas and small cell lung cancer. In one aspect, the invention comprises a method for determining the metastatic potential of a tumor sample, wherein decreased levels of MAP-2 expression in a test sample relative to controls indicates that the sample has increased metastatic potential as compared to the control. In another aspect, the invention comprises a method to prevent tumor progression in metastatic melanoma by increasing levels of MAP-2 protein in cells.
    Type: Application
    Filed: March 20, 2001
    Publication date: December 19, 2002
    Inventors: Vijayasaradhi Setaluri, Dong Fang, Wain White