Patents by Inventor Wakae Yokoi

Wakae Yokoi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10293004
    Abstract: A butyrate-producing bacterium belonging to Anaerostipes hadrus is provided. The amount of butyrate produced is at least 1.5 times that of Anaerostipes hadrus YIT 10092T (DSM 3319T) and is measured by thawing a frozen stock solution of the bacterial strain (a 10% (w/v) skim milk-2% sodium glutamate solution with suspended bacterial cells) (cell count: 2.0 to 5.5×1010 cells/mL), inoculating the solution at 1% to 4 mL of a PY liquid medium supplemented with 33 mM sodium acetate and 0.5 (w/v) % glucose (PYGA medium), followed by anaerobic culture at 37° C. for 24 hours, then inoculating the culture solution at 1% to a PYGA medium, followed by anaerobic culture at 37° C. for 24 hours, then inoculating the culture solution at 1% to a PY medium containing 33 mM sodium acetate and 0.5 (w/v) % L-sorbose, followed by anaerobic culture at 37° C. for 24 hours, and then measuring the butyrate concentration.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: May 21, 2019
    Assignee: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Tadashi Sato, Shiro Kusuhara, Wakae Yokoi, Masahiko Ito, Kouji Miyazaki, Akira Kushiro
  • Publication number: 20170246220
    Abstract: A butyrate-producing bacterium belonging to Anaerostipes hadrus is provided. The amount of butyrate produced is at least 1.5 times that of Anaerostipes hadrus YIT 10092T (DSM 3319T) and is measured by thawing a frozen stock solution of the bacterial strain (a 10% (w/v) skim milk-2% sodium glutamate solution with suspended bacterial cells) (cell count: 2.0 to 5.5×1010 cells/mL), inoculating the solution at 1% to 4 mL of a PY liquid medium supplemented with 33 mM sodium acetate and 0.5 (w/v) % glucose (PYGA medium), followed by anaerobic culture at 37° C. for 24 hours, then inoculating the culture solution at 1% to a PYGA medium, followed by anaerobic culture at 37° C. for 24 hours, then inoculating the culture solution at 1% to a PY medium containing 33 mM sodium acetate and 0.5 (w/v) % L-sorbose, followed by anaerobic culture at 37° C. for 24 hours, and then measuring the butyrate concentration.
    Type: Application
    Filed: March 27, 2015
    Publication date: August 31, 2017
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Tadashi SATO, Shiro KUSUHARA, Wakae YOKOI, Masahiko ITO, Kouji MIYAZAKI, Akira KUSHIRO
  • Patent number: 7754204
    Abstract: Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
    Type: Grant
    Filed: May 22, 2008
    Date of Patent: July 13, 2010
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Haruji Sawada, Yasuto Yoshida, Yasue Wada, Kenji Ohishi, Masahiko Itoh, Wakae Yokoi, Tsunekazu Watanabe
  • Publication number: 20080260709
    Abstract: Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
    Type: Application
    Filed: May 22, 2008
    Publication date: October 23, 2008
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Haruji SAWADA, Yasuto Yoshida, Yasue Wada, Kenji Ohishi, Masahiko Itoh, Wakae Yokoi, Tunekazu Watanabe
  • Patent number: 7413740
    Abstract: Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
    Type: Grant
    Filed: July 8, 2005
    Date of Patent: August 19, 2008
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Haruji Sawada, Yasuto Yoshida, Yasue Wada, Kenji Ohishi, Masahiko Itoh, Wakae Yokoi, Tunekazu Watanabe
  • Patent number: 7101544
    Abstract: Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
    Type: Grant
    Filed: July 19, 2000
    Date of Patent: September 5, 2006
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Haruji Sawada, Yasuto Yoshida, Yasue Wada, Kenji Ohishi, Masahiko Itoh, Wakae Yokoi, Tunekazu Watanabe
  • Publication number: 20060068047
    Abstract: An adsorbent for endocrine disruptors which contains as the active ingredient viable or dead cells of intestinal microorganisms or constituents thereof. When the adsorbent for endocrine disruptors and foods and drinks containing the same are orally taken either daily or simultaneously with endocrine disruptors typified by bisphenols, alkylphenols and triazines and foods and drinks contaminated therewith, the absorption of these endocrine disruptors into the body can be inhibited and the discharge from the body of the endocrine disruptors, which have been once incorporated into the body, can be promoted.
    Type: Application
    Filed: October 11, 2005
    Publication date: March 30, 2006
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Kenji Ohishi, Haruji Sawada, Wakae Yokoi, Yasuto Yoshida, Tsunekazu Watanabe
  • Publication number: 20050244426
    Abstract: Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
    Type: Application
    Filed: July 8, 2005
    Publication date: November 3, 2005
    Applicant: KABUSHIKI KAISHA YAKULT HONSHA
    Inventors: Haruji Sawada, Yasuto Yoshida, Yasue Wada, Kenji Ohishi, Masahiko Itoh, Wakae Yokoi, Tunekazu Watanabe
  • Publication number: 20030133921
    Abstract: An adsorbent for endocrine disruptors which contains as the active ingredient viable or dead cells of intestinal microorganisms or constituents thereof. When the adsorbent for endocrine disruptors and foods and drinks containing the same are orally taken either daily or simultaneously with endocrine disruptors typified by bisphenols, alkylphenols and triazines and foods and drinks contaminated therewith, the absorption of these endocrine disruptors into the body can be inhibited and the discharge from the body of the endocrine disruptors, which have been once incorporated into the body, can be promoted.
    Type: Application
    Filed: November 18, 2002
    Publication date: July 17, 2003
    Inventors: Kenji Ohishi, Haruji Sawada, Wakae Yokoi, Yasuto Yoshida, Tsunekazu Watanabe