Patents by Inventor Wakako Ichikawa

Wakako Ichikawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140322775
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Application
    Filed: March 25, 2014
    Publication date: October 30, 2014
    Applicant: HOKKO CHEMICAL INDUSTRY CO., LTD.
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa
  • Patent number: 8715974
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: May 6, 2014
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa
  • Publication number: 20130196417
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Application
    Filed: March 8, 2013
    Publication date: August 1, 2013
    Applicant: HOKKO CHEMICAL INDUSTRY CO., LTD.
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa
  • Patent number: 8409833
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: April 2, 2013
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa
  • Patent number: 8383368
    Abstract: N-Acetyl-D-glucosamine can be produced by cultivating a fungus capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum AB 10282 strain (FERM BP-10623) or Trichoderma harzianum AB10283 strain (FERM BP-10624), in a culture medium supplemented with a carbon source other than chitin and chitin oligosaccharide and a nitrogen source to produce and accumulate N-acetyl-D-glucosamine in the culture medium and then collecting N-acetyl-D-glucosamine from the culture medium.
    Type: Grant
    Filed: November 11, 2010
    Date of Patent: February 26, 2013
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Tetsuya Mori, Wakako Ichikawa, Yuichi Kita, Yasuyuki Tetsuka
  • Patent number: 7998723
    Abstract: N-Acetyl-D-glucosamine can be produced by cultivating a fungus capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum AB10282 strain (FERM BP-10623) or Trichoderma harzianum AB10283 strain (FERM BP-10624), in a culture medium supplemented with a carbon source other than chitin and chitin oligosaccharide and a nitrogen source to produce and accumulate N-acetyl-D-glucosamine in the culture medium and then collecting N-acetyl-D-glucosamine from the culture medium.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: August 16, 2011
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Tetsuya Mori, Wakako Ichikawa, Yuichi Kita, Yasuyuki Tetsuka
  • Publication number: 20110059489
    Abstract: N-Acetyl-D-glucosamine can be produced by cultivating a fungus capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum AB 10282 strain (FERM BP-10623) or Trichoderma harzianum AB10283 strain (FERM BP-10624), in a culture medium supplemented with a carbon source other than chitin and chitin oligosaccharide and a nitrogen source to produce and accumulate N-acetyl-D-glucosamine in the culture medium and then collecting N-acetyl-D-glucosamine from the culture medium.
    Type: Application
    Filed: November 11, 2010
    Publication date: March 10, 2011
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Tetsuya Mori, Wakako Ichikawa, Yuichi Kita, Yasuyuki Tetsuka
  • Publication number: 20100261238
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to fonts a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Application
    Filed: February 25, 2010
    Publication date: October 14, 2010
    Applicant: HOKKO CHEMICAL INDUSTRY CO., LTD.
    Inventors: MASANORI YAMAGUCHI, YUICHI KITA, TETSUYA MORI, KENJI KANBE, AKIHIRO TOMODA, ATSUSHI TAKAHASHI, WAKAKO ICHIKAWA
  • Patent number: 7745671
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Grant
    Filed: October 14, 2004
    Date of Patent: June 29, 2010
    Assignee: Hokko Chemical Industry Co., Ltd.
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa
  • Publication number: 20100055746
    Abstract: N-Acetyl-D-glucosamine can be produced by cultivating a fungus capable of producing N-acetyl-D-glucosamine, such as Trichoderma hamatum AB10282 strain (FERM BP-10623) or Trichoderma harzianum AB10283 strain (FERM BP-10624), in a culture medium supplemented with a carbon source other than chitin and chitin oligosaccharide and a nitrogen source to produce and accumulate N-acetyl-D-glucosamine in the culture medium and then collecting N-acetyl-D-glucosamine from the culture medium.
    Type: Application
    Filed: July 14, 2006
    Publication date: March 4, 2010
    Applicant: Hokko Chemical Industry Co., Ltd.
    Inventors: Tetsuya Mori, Wakako Ichikawa, Yuichi Kita, Yasuyuki Tetsuka
  • Publication number: 20060240534
    Abstract: It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    Type: Application
    Filed: October 14, 2004
    Publication date: October 26, 2006
    Inventors: Masanori Yamaguchi, Yuichi Kita, Tetsuya Mori, Kenji Kanbe, Akihiro Tomoda, Atsushi Takahashi, Wakako Ichikawa