Patents by Inventor Waldemar Pruzanski

Waldemar Pruzanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibition of excessive phospholipase A.sub.2 activity and/or production by non-antimicrobial tetracyclines
    Patent number: 6043231
    Abstract: A method for treating mammals suffering from conditions associated with excess phospholipase A.sub.2 activity and/or production comprising administering to the mammal an effective amount of a non-antimicrobial tetracycline sufficient to inhibit excess phospholipase A.sub.2 activity and/or production is disclosed. A pharmaceutical composition is also disclosed.
    Type: Grant
    Filed: August 31, 1993
    Date of Patent: March 28, 2000
    Assignee: The Research Foundation of State Univ. of New York
    Inventors: Waldemar Pruzanski, Lorne M. Golub, Peter Vadas, Robert A. Greenwald, Nangavarum S. Ramamurthy, Thomas F. McNamara
  • Antibodies that specifically bind to and inhibit human synovial phospholipase A.sub.2 type A
    Patent number: 5552530
    Abstract: Antibodies that specifically bind to and inhibit the enzymatic activity of synovial phospholipase A.sub.2 Type A are described. The antibodies may be used in assays for detection of synovial phospholipase A.sub.2 in biological samples.
    Type: Grant
    Filed: August 1, 1994
    Date of Patent: September 3, 1996
    Assignee: Eli Lilly & Company
    Inventors: Lorin K. Johnson, Jeffrey J. Seilhamer, Waldemar Pruzanski, Peter Vadas
  • Inhibition of excessive phospholipase A.sub.2 activity and/or production by non-antimicrobial tetracyclines
    Patent number: 5523297
    Abstract: A method for treating mammals suffering from conditions associated with excess phospholipase A.sub.2 activity and/or production comprising administering to the mammal an effective amount of a non-antimicrobial tetracycline sufficient to inhibit excess phospholipase A.sub.2 activity and/or production is disclosed.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: June 4, 1996
    Assignee: The Research Foundation of State University of New York
    Inventors: Waldemar Pruzanski, Lorne M. Golub, Peter Vadas, Robert A. Greenwald, Nangavarum S. Ramamurthy, Thomas F. McNamara
  • Synovial phospholipases
    Patent number: 5019508
    Abstract: Mammalian synovial phospholipase A.sub.2 (sPLA.sub.2) enzymes are provided, as well as DNA constructs encoding these enzymes, methods of producing the enzymes recombinantly, and antibodies thereto. Therapeutic methods employing anti-synovial phospholipase antibodies are also provided, in addition to diagnositc methods and other applications of sPLA.sub.2.
    Type: Grant
    Filed: July 6, 1988
    Date of Patent: May 28, 1991
    Assignees: Biotechnology Research Partners, Ltd., The University of Toronto Innovations Foundation
    Inventors: Lorin K. Johnson, Jeffrey J. Seilhamer, Waldemar Pruzanski, Peter Vadas