Patents by Inventor Walid Kuri-Harcuch

Walid Kuri-Harcuch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7413900
    Abstract: Aspects of the invention provide an immortalized fibroblast cell line capable of the growth and maintenance of human embryonic stem cells. An immortalized fibroblast cell line derived from an early stage mouse embryo is provided. Methods of preparing an immortalized fibroblast cell line from an early stage mouse embryo are also provided.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: August 19, 2008
    Assignee: President and Fellows of Harvard College
    Inventors: Howard Green, Shiro Iuchi, Walid Kuri-Harcuch, Meytha Marsch-Moreno
  • Publication number: 20070098696
    Abstract: Aspects of the invention provide an immortalized fibroblast cell line capable of the growth and maintenance of human embryonic stem cells. An immortalized fibroblast cell line derived from an early stage mouse embryo is provided. Methods of preparing an immortalized fibroblast cell line from an early stage mouse embryo are also provided.
    Type: Application
    Filed: October 31, 2005
    Publication date: May 3, 2007
    Applicant: President and Fellows of Harvard College
    Inventors: Howard Green, Shiro Iuchi, Walid Kuri-Harcuch, Meytha Marsch-Moreno
  • Patent number: 6962775
    Abstract: Methods and products relating the preservation of cultured mammalian epithelial or mesenchymal cells are provided. The methods involve the pre-treatment of epithelial cells with a solution containing a cryoprotectant amount of monosaccharides and/or disaccharides. The treated cells then are frozen, dried or freeze-dried in a minimum volume of solution and stored for later use. The invention avoids the use of materials that must be washed away from the preserved tissue prior to application of the tissue to a wound bed. The invention also permits the storage of epithelial tissue in a dry state.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: November 8, 2005
    Assignee: Advanced Biohealing, Inc.
    Inventors: Walid Kuri-Harcuch, Federico Castro Munozledo, Luis Salazar-Olivio, Meytha Marsch-Moreno
  • Patent number: 6713084
    Abstract: The present invention provides methods for promoting healing of wounds which result from skin resurfacing procedures, e.g., from laser surgery to remove or alter superficial features of the skin. The methods involve the application of a sheet of cultured epithelial cells to the laser skin resurfacing would of a subject in need of such treatment. The methods promote faster healing of skin resurfacing wounds relative to prior art methods of healing such wounds.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: March 30, 2004
    Assignee: Celadon Science, LLC
    Inventors: Walid Kuri-Harcuch, Yesid Bolivar-Flores
  • Patent number: 6582696
    Abstract: Methods and products relating the preservation of cultured mammalian epithelial or mesenchymal cells are provided. The methods involve the pre-treatment of epithelial cells with a solution containing a cryoprotectant amount of monosaccharides and/or disaccharides. The treated cells then are frozen, dried or freeze-dried in a minimum volume of solution and stored for later use. The invention avoids the use of materials that must be washed away from the preserved tissue prior to application of the tissue to a wound bed. The invention also permits the storage of epithelial tissue in a dry state.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: June 24, 2003
    Assignee: Celadon Science, LLC
    Inventors: Walid Kuri-Harcuch, Federico Castro Munozledo, Luis Salazar-Olivio, Meytha Marsch-Moreno
  • Patent number: 6548297
    Abstract: Methods of cryopreserving sheets of cultured epithelial cells are disclosed. The sheets of cultured epithelial cells are used for wound repair. The invention permits the use of preserved tissue without the need to wash away cryopreservation components. The sheets are frozen in contact with a cryoprotectant solution containing a cryoprotectant such as a monosaccharide or a disaccharide.
    Type: Grant
    Filed: September 4, 1997
    Date of Patent: April 15, 2003
    Assignee: Celadon Science, Inc.
    Inventors: Walid Kuri-Harcuch, Federico Castro Munozledo, Luis Salazar-Olivio, Meytha Marsch-Moreno
  • Patent number: 6541028
    Abstract: The present invention provides methods for promoting healing of wounds which result from corneal resurfacing procedures, e.g. from laser surgery to alter refractive of the eye. The methods involve the application of a sheet of cultured epithelial cells to the laser corneal resurfacing wound of a subject in need of such treatment. The methods promote faster healing of corneal resurfacing wounds relative to prior art methods of healing such wounds. The invention also provides corneal wound healing devices having the shape and dimensions of a contact lens.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: April 1, 2003
    Assignee: Celadon Science, LLC
    Inventors: Walid Kuri-Harcuch, Federico Castro Munozledo
  • Publication number: 20020192197
    Abstract: Methods and products relating the preservation of cultured mammalian epithelial or mesenchymal cells are provided. The methods involve the pre-treatment of epithelial cells with a solution containing a cryoprotectant amount of monosaccharides and/or disaccharides. The treated cells then are frozen, dried or freeze-dried in a minimum volume of solution and stored for later use. The invention avoids the use of materials that must be washed away from the preserved tissue prior to application of the tissue to a wound bed. The invention also permits the storage of epithelial tissue in a dry state.
    Type: Application
    Filed: June 20, 2002
    Publication date: December 19, 2002
    Inventors: Walid Kuri-Harcuch, Federico Castro Munozledo, Luis Salazar-Olivio, Meytha Marsch-Moreno
  • Publication number: 20020192191
    Abstract: Methods and products relating the preservation of cultured mammalian epithelial or mesenchymal cells are provided. The methods involve the pre-treatment of epithelial cells with a solution containing a cryoprotectant amount of monosaccharides and/or disaccharides. The treated cells then are frozen, dried or freeze-dried in a minimum volume of solution and stored for later use. The invention avoids the use of materials that must be washed away from the preserved tissue prior to application of the tissue to a wound bed. The invention also permits the storage of epithelial tissue in a dry state.
    Type: Application
    Filed: June 20, 2002
    Publication date: December 19, 2002
    Inventors: Walid Kuri-Harcuch, Federico Castro, Luis Salazar-Olivio, Meytha Marsch-Moreno
  • Patent number: 5030105
    Abstract: A process is disclosed for the long term surviving culture of hepatocytes maintaining their morphological and functional characteristics for long-term-periods, suitable to assest the acute and chronic hepatotoxicity of drugs, chemicals and environmental pollutants. The long term surviving culture of hepatocytes is carried out in a culture media containing fibroblast cells or fibroblast cell products treated to prevent cell multiplication and inoculated under controlled density.
    Type: Grant
    Filed: November 15, 1989
    Date of Patent: July 9, 1991
    Assignee: Centro de Investigacion y Estudios Avanzados del Instituto Politecnico Nacional
    Inventors: Walid Kuri-Harcuch, Tomas Mendoza-Figueroa
  • Patent number: 4914032
    Abstract: A process is disclosed for the long term surviving culture of hepatocytes maintaining their morphological and functional characteristics for long-term periods, suitable to assest the acute and chronic hepatotoxicity of drugs, chemicals and environmental pollutants. The long term surviving culture of hepatocytes is carried out in a culture media containing fibroblast cells or fibroblast cell products treated to prevent cell multiplication and inoculated under controlled density.
    Type: Grant
    Filed: June 6, 1985
    Date of Patent: April 3, 1990
    Assignee: Centro de Investigation Y Estudios Avanzados Del Instituto Politecnico Nacional
    Inventors: Walid Kuri-Harcuch, Tomas Mendoza-Figueroa