Patents by Inventor Walid WARDA

Walid WARDA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CAR-T cells targeting IL-1RAP and their use in acute myeloid leukemia (AML)
    Patent number: 12774339
    Abstract: The present invention is relative to a cell comprising a nucleic acid molecule encoding a chimeric antigen receptor (CAR) for use in the treatment of acute myeloid leukemia (AML), wherein the CAR comprises an antibody or antibody fragment which includes an anti-IL-1RAP binding domain, a transmembrane domain, and an intracellular signaling domain comprising at least a stimulatory domain
    Type: Grant
    Filed: May 27, 2020
    Date of Patent: October 27, 2026
    Assignees: ETABLISSEMENT FRANCAIS DU SANG, INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE BESANCON, UNIVERSITE DE FRANCHE-COMTE
    Inventors: Marina Deschamps, Christophe Ferrand, Fabrice Larosa, Walid Warda
  • T-CELLS COMPRISING CHIMERIC ANTIGEN RECEPTORS AND COMPOSITIONS THEREOF FOR TREATMENT OF CANCER
    Publication number: 20260241001
    Abstract: T-cells comprising chimeric antigen receptors (CARs) for the treatment of cancer. The CARs include a Protein Tyrosine Phosphatase Receptor Type D (PTPRD) domain or a single chain variable fragment of an antibody that binds to IL-1RAP expressed by cancer cells, a transmembrane domain, and domains or fragments of co-stimulatory molecules. The CAR T-cells have high specificity for IL1-1RAP expressed on the surface of cancer cells. Nucleic acids and vectors encoding the CAR T-cells and a method for production of the CAR T-cells are additional aspects.
    Type: Application
    Filed: February 20, 2025
    Publication date: August 20, 2026
    Applicant: KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTRE
    Inventors: Walid WARDA, Farhatullah SYED, Syed Osman AHMED, Ayodele Abdulkareem ALAIYA, Hazaa ALZAHRANI, Hanan ALQUDAIRY
  • CAR-T CELLS TARGETING IL-1RAP AND THEIR USE IN ACUTE MYELOID LEUKEMIA (AML)
    Publication number: 20220235138
    Abstract: The present invention is relative to a cell comprising a nucleic acid molecule encoding a chimeric antigen receptor (CAR) for use in the treatment of acute myeloid leukemia (AML), wherein the CAR comprises an antibody or antibody fragment which includes an anti-IL-1RAP binding domain, a transmembrane domain, and an intracellular signaling domain comprising at least a stimulatory domain
    Type: Application
    Filed: May 27, 2020
    Publication date: July 28, 2022
    Inventors: Marina DESCHAMPS, Christophe FERRAND, Fabrice LAROSA, Walid WARDA